|
HS Code |
804734 |
| name | VcMMAE |
| type | Antibody-Drug Conjugate (ADC) payload linker |
| full_name | Valine-citrulline-monomethyl auristatin E |
| payload | Monomethyl auristatin E (MMAE) |
| linker_type | Cleavable dipeptide linker |
| mechanism_of_action | Microtubule disruption |
| cleavage_mechanism | Cathepsin B cleavable |
| usage | Conjugated to monoclonal antibodies for targeted cancer therapy |
| hydrophobicity | High |
| solubility | Low in water |
| stability | Stable in plasma, cleaved in lysosomes |
| clinical_application | Used in ADC drugs such as Brentuximab vedotin |
| CAS_number | 646502-53-6 |
As an accredited VcMMAE factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | VcMMAE is supplied in a 1 mg amber glass vial, sealed with a screw cap, labeled with chemical information and manufacturer details. |
| Shipping | VcMMAE from Sigma Aldrich, Merck, or TCI Chemical Grade is shipped in secure, leak-proof containers, compliant with international hazardous material regulations. Packaging ensures product stability, protection from light and moisture, and clear labeling for safe handling. Temperature-sensitive, it may ship with coolant or on dry ice, depending on destination and supplier. |
| Storage | VcMMAE should be stored at -20°C in a tightly sealed, light-protected container to maintain stability and prevent degradation. Ensure the chemical is kept in a dry environment away from incompatible substances. Handle under a fume hood wearing appropriate personal protective equipment. Always refer to the manufacturer's Material Safety Data Sheet (MSDS) for specific storage and handling recommendations. |
Competitive VcMMAE prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615371019725 or mail to sales7@bouling-chem.com.
We will respond to you as soon as possible.
Tel: +8615371019725
Email: sales7@bouling-chem.com
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