|
HS Code |
804734 |
| Name | VcMMAE |
| Type | Antibody-Drug Conjugate (ADC) payload linker |
| Full Name | Valine-citrulline-monomethyl auristatin E |
| Payload | Monomethyl auristatin E (MMAE) |
| Linker Type | Cleavable dipeptide linker |
| Mechanism Of Action | Microtubule disruption |
| Cleavage Mechanism | Cathepsin B cleavable |
| Usage | Conjugated to monoclonal antibodies for targeted cancer therapy |
| Hydrophobicity | High |
| Solubility | Low in water |
| Stability | Stable in plasma, cleaved in lysosomes |
| Clinical Application | Used in ADC drugs such as Brentuximab vedotin |
| Cas Number | 646502-53-6 |
As an accredited VcMMAE factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | VcMMAE is supplied in a 1 mg amber glass vial, sealed with a screw cap, labeled with chemical information and manufacturer details. |
| Shipping | VcMMAE from Sigma Aldrich, Merck, or TCI Chemical Grade is shipped in secure, leak-proof containers, compliant with international hazardous material regulations. Packaging ensures product stability, protection from light and moisture, and clear labeling for safe handling. Temperature-sensitive, it may ship with coolant or on dry ice, depending on destination and supplier. |
| Storage | VcMMAE should be stored at -20°C in a tightly sealed, light-protected container to maintain stability and prevent degradation. Ensure the chemical is kept in a dry environment away from incompatible substances. Handle under a fume hood wearing appropriate personal protective equipment. Always refer to the manufacturer's Material Safety Data Sheet (MSDS) for specific storage and handling recommendations. |
Competitive VcMMAE prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365186327 or mail to sales3@ar-reagent.com.
We will respond to you as soon as possible.
Tel: +8615365186327
Email: sales3@ar-reagent.com
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