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DEXTRAN STANDARD 270000 is a chemically synthesized polysaccharide, classified as a high molecular weight, water-soluble polymer. Its chemical formula is designated as (C6H10O5)n, reflecting the repetitive glucose units bound together in its linear and branched chains. With an average molecular weight near 270,000 Daltons, this material stands out in both purity and consistency. It appears as a solid—typically a faint white or off-white powder, but chemists have seen it supplied as flakes, dense crystals, or pellets, depending on production and intended usage. One might find it described as a raw material, but that label only scratches the surface. Anyone in a biochemistry or clinical lab knows dextran as a daily workhorse.
Physical properties matter when working in a laboratory setting. DEXTRAN STANDARD 270000 dissolves in water with high affinity, creating clear, viscous solutions. Its solubility helps it find its way into gels, plasma substitute solutions, and various biotechnological platforms. Density comes in at about 1.2 g/cm³ for the dry solid, varying slightly with humidity and granule packing. Whether found as powder, flakes, or compacted pearls—the texture stems from crystallization and drying methods during manufacturing rather than chemical or structural variation. In solution, viscosity depends on both concentration and temperature, meaning precise measurement always makes a difference. Chemically, dextran consists of α-(1→6) glycosidic linkages for its main chain, with occasional α-(1→3) branching. These structural quirks give it unique combinations of strength, flexibility, and hydration capacity.
Every inch of DEXTRAN STANDARD 270000 complies with tight controls for purity—impurities, moisture content, and molecular weight distribution must all stay within established specs. Batch-to-batch consistency gets checked using advanced chromatography, and reported specifications detail the product’s molecular size distribution and moisture content. In commerce, its HS Code usually appears as 3913900090, listed under “other natural polymers.” Storage guidelines stress keeping it in airtight containers, away from sources of moisture, since dextran is hygroscopic and will clump or degrade if exposed to humid conditions. The raw material’s particulate form makes it non-hazardous; inhaling small amounts of airborne dust could cause irritation, but serious health risks don’t usually come up in the day-to-day lab environment. The compound earns a solid “safe” rating for standard laboratory practice, though it’s always best to follow established chemical handling protocols, wear eye protection when pouring, and wash hands to prevent ingestion.
In the biomedical lab, DEXTRAN STANDARD 270000 rarely sits on the shelf for long. Professionals lean on its macromolecular consistency and chemical predictability while preparing calibration curves for size exclusion chromatography or serving as a viscosity builder in electrophoresis. Blood banks and hospitals sometimes reach for dextran-derived solutions to expand plasma volume or as carriers in vaccine development. Biochemistry applications use its high molecular weight to simulate complex biomacromolecules or to stabilize proteins. Material scientists appreciate its performance when formulating hydrogels or as a template for nanoparticle synthesis. Each function draws directly from its physical and chemical make-up—the molecule's sheer size and sturdy glucose backbone allow it to perform in places where many other polysaccharides would fail.
The molecular backbone of DEXTRAN STANDARD 270000 runs long and flexible, a chain of countless C6H10O5 repeats. This formula tells you it’s a polymer built for adaptability. The density difference between its solid and hydrated forms explains its wide range of applications. In my experience, weighing out dry powder and watching it vanish into an aqueous solution always reinforces how much water this material can hold and how dramatically it affects fluid viscosity. Manufacturers produce it in stable, free-flowing solids; it resists clumping and does not spontaneously degrade under normal storage. As a dry product, it feels slightly grainy or silky to the touch, depending on processing, and pours much like confectioner’s sugar.
Many researchers face the daily challenge of handling bulk chemicals without incident. Though DEXTRAN STANDARD 270000 poses minimal risk, good practice cannot slide. Keeping workspaces dry, wearing gloves, and ensuring storage bins remain tightly sealed reduces both contamination and waste. Since dust can irritate mucous membranes, a basic dust mask or hood extraction helps during weighing. Spills clean up easily with water, but lab coats and goggles also protect against unexpected splashes, especially with concentrated solutions. Standard safety data points give this material a non-toxic rating, and no special disposal requirements usually apply. Still, local regulations may treat large-volume disposal as controlled waste just for record keeping—a habit that helps prevent mishandling across the supply chain.
One of the real challenges comes in guaranteeing consistent molecular weights batch after batch. Small shifts in fermentation temperatures or enzyme concentrations during synthesis can nudge the size distribution and affect downstream results. For labs running calibration protocols or pharmacological tests, those little differences wreak havoc on repeatability. Quality control labs invest heavily in analytical equipment—size exclusion chromatography with multi-angle laser light scattering or refractive index detectors—just to check every new lot that arrives. Suppliers publishing full certificates of analysis for molecular weight, polydispersity, and moisture content help ease this process and anchor trust. Pressure always pushes suppliers to bundle tighter specs with larger orders for industrial projects. Research teams benefit when manufacturers listen, openly share batch data, and allow easy returns if a shipment drifts from target properties.
For anyone new to large polysaccharides, dextran’s performance makes an impression. Its strong hydration beats many synthetic polymers, letting formulators design slow-release drug coatings or tissue scaffolds with tailored water content. Food and pharmaceutical uses focus on its non-toxicity and compatibility with living cells. Drawbacks crop up with sourcing pure, pyrogen-free grades for clinical applications, or when cost per kilogram climbs in high-purity lots. Environmental safety generally ranks high because the compound biodegrades; landfill disposal brings little risk, though some residue may affect wastewater filters if disposed of in concentrated form. For my own part, a solid partnership with chemical suppliers always made challenges easier: picking up the phone, clarifying grade requirements, asking for full material safety data, and keeping a set of test kits on hand for in-house confirmation.
Chemical Name: Dextran Standard 270000
Molecular Formula: (C6H10O5)n
Average Molecular Weight: ~270,000 Da
Physical State: Powder, flakes, pearls, or solid crystals
Color: White to off-white
Density: ~1.2 g/cm³
Solubility: Highly soluble in water
HS Code: 3913900090
Structural Details: Linear and branched α-glucan, primarily α-(1→6) linkages
Safe Handling: Non-toxic, low hazard; dust mask, gloves, standard lab protocols recommended
Environmental Impact: Biodegradable, low risk on disposal
