© 2026 Nanjing Finechem Holdings Co., Ltd,
All Right Reserved
Product Name: Tyrosinase
Synonyms: Polyphenol oxidase, Monophenol monooxygenase
CAS Number: 9002-10-2
Recommended Use: Laboratory research, food processing, pharmaceuticals
Manufacturer/Supplier: Refer to label information on supply container
Emergency Contact: Refer to regional poison control center and manufacturer’s emergency hotline
Classification: Not classified as hazardous under GHS criteria
Signal Word: No signal word required
Hazard Statements: May cause respiratory tract irritation, mild skin or eye irritation on prolonged contact
Pictograms: None assigned under standard classification
Precautionary Statements: Prevent inhalation of enzyme powder or aerosols, avoid contact with eyes and skin, use in a ventilated space
Potential Health Effects: Sensitization reactions in previously exposed individuals, occasional allergic response
Chemical Identity: Tyrosinase
Purity: Typically >90% by enzyme activity assay
Other Components: Trace stabilizers and buffer salts, less than 10%
Molecular Weight: Approx. 60 kDa (varies with source)
Impurities: None known of toxicological significance; minor protein contaminants possible depending on preparation
Formula: Derived from fungal, plant, or animal sources, batch dependent
Inhalation: Move to fresh air as soon as symptoms develop; seek medical advice if respiratory irritation persists
Skin Contact: Wash with water and mild soap; remove contaminated clothing; if irritation persists, contact healthcare provider
Eye Contact: Rinse cautiously with clean water for several minutes, lift eyelids occasionally, consult a physician if irritation remains
Ingestion: Rinse mouth thoroughly with water; do not induce vomiting; seek medical attention if symptoms develop
Special Instructions: Provide symptomatic and supportive care; carry product label or MSDS to healthcare providers
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Specific Hazards: Proteinaceous material can decompose to form carbon oxides and nitrogen oxides
Protective Equipment for Firefighters: Wear self-contained breathing apparatus, chemical resistant suit and gloves
Unusual Fire/Explosion Hazards: Powder may form combustible dust-air mixtures in large quantities; low risk under lab-scale use
Advice for Firefighters: Avoid dust generation, use water mist to cool exposed containers; prevent runoff contamination
Personal Precautions: Wear protective gloves, safety goggles, laboratory coat, and avoid inhaling powders or aerosols
Environmental Precautions: Prevent run-off into surface water or drainage systems; contain spills with absorbent materials
Cleanup Procedures: Sweep up the released powder carefully and place in a suitable waste container; ventilate the area and wash residues with water; avoid raising dust
Disposal Method: Collect residues in a properly sealed, labeled bag or plastic drum for proper disposal; consult local regulations on proteinaceous enzyme waste
Handling: Minimize dust formation, use laboratory fume hood if available, prevent inhalation and direct skin contact
Safe Practices: Wear protective equipment, avoid eating, drinking, or smoking in laboratory; always wash hands after handling
Storage: Store at -20°C for long term (or as indicated by provider), sealed tightly, protect from light and moisture, label containers clearly
Incompatible Materials: Strong oxidizers, acids and bases; avoid contact with reactive agents that could denature enzyme
Designated Storage Areas: Secure, ventilated, limited access to trained personnel
Occupational Exposure Limits: No established national or international limits, use exposure minimization protocols
Engineering Controls: Use of local exhaust ventilation or fume hood, keep containers closed when not in use
Personal Protective Equipment: Lab coat, nitrile or latex gloves, chemical splash goggles
Respiratory Protection: Dust mask or particulate respirator recommended during dusty operations or spill cleanup
Hygiene Measures: Wash thoroughly after handling, remove contaminated clothing, decontaminate surfaces
Appearance: Off-white to light brown powder or freeze-dried cake
Odor: Mild, organic, proteinaceous
pH (solution): 6.0–7.5 (typical working buffer)
Melting Point/Freezing Point: Not applicable (protein denatures at elevated temperature rather than melting)
Solubility: Soluble in aqueous buffer solutions, insoluble in most organic solvents
Boiling Point: Not applicable
Flash Point: Not relevant for protein powders
Explosive Properties: Not classed as explosive, though fine powders can form dust clouds
Decomposition Temperature: Loss of enzymatic activity above 50°C
Auto-ignition Temperature: Not determined for pure enzyme
Chemical Stability: Stable under normal laboratory and storage conditions (frozen, protected from moisture)
Conditions to Avoid: Prolonged exposure to air, high temperatures, direct sunlight, acidic or basic solutions
Incompatible Materials: Strong oxidizing agents, acids, base, heavy metals
Hazardous Decomposition Products: Thermal decomposition emits nitrogen oxides, carbon dioxide and monoxide
Reactivity: Not reactive under prescribed handling; enzyme activity lost on exposure to denaturants or oxidizers
Acute Toxicity: Oral, dermal and inhalation toxicity not fully determined though generally considered low by analogy to similar proteins
Chronic Effects: Long-term exposure may promote respiratory sensitization in susceptible individuals
Skin Contact: May cause mild, transient irritation
Eye Contact: May result in redness, mild discomfort
Inhalation: Prolonged exposure to airborne dust may induce allergic reactions or respiratory symptoms
Ingestion: Low toxicity anticipated; swallowing large quantities discouraged
Carcinogenic, Mutagenic, Reproductive Toxicity: No evidence currently reported for tyrosinase
Target Organs: Eyes, skin, respiratory tract
Ecotoxicity: Not expected to be hazardous at low concentrations based on enzyme origin (biodegradable protein)
Persistence and Degradability: Readily biodegradable by microbial action and natural processes
Bioaccumulative Potential: No significant bioaccumulation expected
Mobility in Soil: Moderate; quickly degraded in biological environments
Aquatic Toxicity: Limited data, but generally low environmental impact; breakdown products are amino acids and peptides
Other Harmful Effects: None identified
Waste Treatment Methods: Dispose in accordance with local, regional, or national legislation; treat as laboratory chemical waste
Waste Packaging: Use leak-proof, clearly labeled containers for surplus and spill cleanup materials
Environmental Precautions: Do not flush large amounts into sewer, soil, or watercourses; treat as organic lab waste, incinerate or landfill if approved by authority
Special Disposal Notes: Consult approved chemical disposal contractors for large quantities; confirm non-hazardous status if possible
UN Number: Not regulated for transport
Proper Shipping Name: Tyrosinase, not restricted
Transport Hazard Class: Not classified as dangerous goods
Packing Group: Not applicable
Special Precautions: Avoid container damage, protect from water and direct sunlight during shipping
Transport Labeling: Normal laboratory chemical labeling, not hazardous labels required
International Inventories: Refer to country-specific chemical inventories (TSCA, EINECS), typically listed for research use
Labeling Requirements: Proper chemical name, required hazard information, recommended precautions
Other Regulations: Subject to laboratory safety guidelines, occupational safety rules for exposure and PPE
Country-Specific Notes: Certain regions regulate enzymes as possible allergens or biological agents; consult national guidelines
SARA Title III, CERCLA, RCRA: Not listed as a hazardous substance under US federal regulations
REACH Compliance: Exempt for research or development quantities; full compliance necessary for industrial-scale use
