© 2026 Nanjing Finechem Holdings Co., Ltd,
All Right Reserved
Substance Name: 5-Hydroxytryptamine Hydrochloride
Chemical Formula: C10H12N2O·HCl
Common Name: Serotonin Hydrochloride
Physical Appearance: White to off-white crystalline powder
Common Usage: Research in neuroscience, biochemical studies, precursor in serotonin research
Odor: Almost odorless
Relevant Synonyms: Serotonin chloride
CAS Number: 153-98-0
GHS Classification: Not assigned for consumer use, primarily found in research settings
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Potential Health Effects: May cause respiratory tract irritation, eye and skin irritation, possible headaches, and nausea if inhaled or ingested
Signal Words and Pictograms: Laboratory labels typically recommend caution; standard hazard pictograms apply for irritants
Main Hazards: Dust can irritate airways, research exposure mainly affects those unprotected in laboratory environments
Other Risks: Product might sensitize the skin over prolonged or repeated contact
Chemical: 5-Hydroxytryptamine Hydrochloride
Purity: Usually greater than 98% in laboratory use
Impurities: Small traces of related compounds may be present, but bulk is active ingredient
Structure: Indoleamine compound containing amine and hydroxyl functional groups
Skin Contact: Remove contaminated clothing, rinse skin with copious water and soap; irritation may develop if ignored
Eye Contact: Rinse generously with water for several minutes, keep eyelids open, seek medical attention for persistent discomfort
Inhalation: Relocate to fresh air, monitor for respiratory symptoms, consider professional care for coughing, dizziness, or persistent irritation
Ingestion: Rinse mouth, do not trigger vomiting, medical evaluation if significant amount consumed or if symptoms arise
Extinguishing Media: CO2, dry chemical, or foam preferred; water spray may help reduce dust
Hazardous Decomposition: Burning releases toxic gases like nitrogen oxides, hydrogen chloride, carbon monoxide
Protective Equipment: Firefighters recommend self-contained breathing apparatus and standard protective gear in case of fire
Fire Hazards: Product does not present flammable risk under normal conditions, although powder in air creates dust explosion risk
Personal Precautions: Avoid breathing dust, wear gloves and laboratory safety goggles
Environmental Precautions: Keep out of drains and soil to prevent chemical burden to the environment
Spill Cleanup: Use damp cloths or absorbent material for powder, collect for disposal, ventilate area during cleanup
Dust Control: Minimize contact and spread through gentle cleanup; careless sweeping can raise dust clouds
Safe Handling: Work in well-ventilated areas, use tools to transfer powder, reduce dust with careful dispensing
Hygienic Practices: Wash hands after use, avoid eating or drinking in lab spaces, keep surface decontaminated
Storage Requirements: Store in tightly closed bottles, protect from moisture, keep in cool, dry, dark place, segregate from incompatible substances
Cross-Contamination: Tools and surfaces should be cleaned after handling, as even trace amounts can cause problems for sensitive biological experiments
Engineering Controls: Fume hoods or adequate exhaust systems, minimize airborne particles with local ventilation
Personal Protection – Eyes: Laboratory goggles strongly recommended
Personal Protection – Skin: Chemical-resistant gloves, lab coats, closed shoes
Respiratory Protection: Masks or respirators if dust becomes airborne; not usually required under normal lab manipulation if containment is good
Tyical Exposure Limits: No established occupational exposure limits, so prudent laboratory hygiene rules apply
Appearance: Fine white to off-white crystalline powder
Molecular Weight: 212.68 g/mol
Melting Point: Approximately 167 to 168°C
Boiling Point: Not applicable for stable solids
Solubility: Freely soluble in water, sparingly soluble in ethanol, limited in organic solvents
Odor Threshold: No evidence of strong odor threshold
pH of Solution: Neutral to slightly acidic due to hydrochloride salt
Vapor Pressure: Negligible
Flash Point: Data not readily available due to solid form
Chemical Stability: Stable under recommended storage conditions; will degrade over time when exposed to light or moisture
Reactive Hazards: Strong oxidizers may trigger reactions
Decomposition: Prolonged heating or burning results in breakdown to potentially toxic gases
Incompatible Materials: Strong acids and bases, strong oxidizing agents, direct sunlight, and excess heat
Acute Toxicity: Low toxicity in small quantities as found in laboratory research; impacts may rise with increasing exposure
Local Effects: Can irritate skin, eyes, and respiratory system; symptoms often transient with basic precautions
Chronic Effects: Data from extended repeated dosing is lacking; minimize exposure to avoid unknown risks
Sensitization: Rare, but some users may experience allergic-like response on skin contact
Carcinogenicity, Mutagenicity, Reproductive Effects: No comprehensive studies, so prudent avoidance of unnecessary exposure stays the best policy
Aquatic Toxicity: Water solubility means some risk to aquatic organisms; acute toxicity estimated low, but chronic exposure could still disrupt local ecosystems
Environmental Behavior: Degrades slowly in soil or water, and typical lab use does not generate high release levels when rules followed
Persistence and Degradability: Breakdown requires time and microbial action; careful disposal always recommended
Bioaccumulation: Not expected to bioaccumulate in animal tissues based on chemical structure and metabolic breakdown
Safe Disposal: Collect waste material into solid chemical disposal containers lined with compatible bags, label clearly
Waste Handling: Chemical disposal best performed following local regulations; incineration under controlled conditions or delivery to hazardous waste facility advised
Cleanup: Standard contamination prevention practices—avoid washing large quantities into drains or sewers, as wastewater treatment might not destroy all material
Precaution for Transport: Package in sealed, reinforced containers, with padding to limit vibration and breakage
Transport Regulations: Not specifically regulated under ADR, IATA, IMDG, or DOT categories for small research quantities
Packing Group and Labeling: Inner packaging should withstand normal transport hazards, secondary containment for spills
Chemical Inventory Status: Included in main chemical registries in North America, Europe, and Asia for research use
International Regulation: No global bans, but countries impose controls as an amine derivative and precursor for biological studies
Workplace Controls: Enforcement depends on lab policy, guided by best practice for universities and industrial research
Other Legal Notes: Direct human consumption not approved; use strictly for laboratory and experimental purposes per local and international law
