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Product Name: Trisodium Citrate Dihydrate
Chemical Formula: C6H5Na3O7·2H2O
Synonyms: Sodium Citrate, Citrosodine, Trisodium Salt of Citric Acid
CAS Number: 6132-04-3
Recommended Use: Used as a food additive, anticoagulant, buffering agent, and emulsifier in pharmaceuticals and laboratories
Manufacturer Contact: Refer to supplier’s documentation for current contact details
Classification: Not classified as hazardous under GHS
GHS Label Elements: No pictogram, signal word, or hazard statement required
Potential Health Effects: May cause mild eye and skin irritation, inhalation can produce coughing or discomfort, ingestion of large amounts may lead to gastric upset
NFPA Ratings: Health 1, Flammability 0, Reactivity 0
Symptoms: Irritation, redness, stomach pain, or nausea in sensitive individuals
Chemical Name: Trisodium Citrate Dihydrate
Concentration: Greater than 99%
Impurities: Very minor traces of citric acid or monosodium/disodium citrate
Molecular Weight: 294.10 g/mol
Purity: Food and pharmaceutical grade as supplied unless otherwise specified
Eye Contact: Rinse gently with plenty of clean water for several minutes, hold eyelids open, seek medical advice if discomfort continues
Skin Contact: Remove contaminated clothing, wash skin thoroughly with water and mild soap
Inhalation: Move to fresh air, support breathing with comfortable posture, get medical attention if symptoms persist
Ingestion: Rinse mouth, drink water to dilute, do not induce vomiting, consult a doctor for persistent discomfort
Note to Physicians: Treat symptomatically, product has low toxicity but may aggravate gastric distress if ingested in quantity
Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical, or foam
Hazards from Combustion: Emits carbon oxides and sodium oxides if strongly heated
Protective Equipment: Firefighters should use self-contained breathing apparatus and full protective clothing
Firefighting Advice: Fight fire from upwind side, keep containers cool using water spray, prevent run-off from entering drains or watercourses
Flash Point: Not flammable
Explosion Limits: Not applicable due to non-combustible nature
Personal Precautions: Avoid dust formation, prevent contact with eyes and skin, use appropriate PPE such as gloves and safety goggles
Environmental Precautions: Prevent large spills from entering waterways, inform authorities if product contaminates lakes, rivers, or drains
Spill and Leak Procedures: Sweep up gently, avoid raising dust, collect into suitable containers for reuse or disposal, clean spill area thoroughly with water
Waste Disposal: See section on Disposal Considerations for further guidance
Handling: Keep packaging tightly closed, minimize dust generation, handle in areas with adequate ventilation, wash hands thoroughly after handling
Storage: Store in cool, dry, well-ventilated place, away from strong acids and bases, avoid moisture exposure to prevent clumping or caking
Incompatible Products: Acids, strong oxidizers
Storage Temperature: Room temperature or below 25°C recommended
Special Requirements: Store in food-grade bags or containers for products intended for consumption or pharmaceutical use
Occupational Exposure Limits: No specific limits set; maintain airborne concentrations as low as reasonably possible
Engineering Controls: Use local exhaust ventilation or general room ventilation to reduce dust
Personal Protective Equipment: Wear protective gloves, safety goggles, and lab coat
Respiratory Protection: Use particulate filter respirator if dust levels get high or ventilation is insufficient
Hygiene Measures: Do not eat, drink, or smoke in work area, wash hands and face before breaks or after handling the product
Appearance: White crystalline powder or granules
Odor: Odorless
pH (5% solution): Around 8.5
Melting Point: Decomposes at 150°C (anhydrous salt)
Boiling Point: Not applicable
Solubility: Soluble in water (61 g/100 mL at 25°C), practically insoluble in alcohol
Bulk Density: Around 1.71 g/cm³
Vapor Pressure: Negligible
Partition Coefficient (n-octanol/water): Not determined for dihydrate
Chemical Stability: Stable under recommended conditions
Possibility of Hazardous Reactions: May react with strong acids to release carbon dioxide
Conditions to Avoid: Moisture, excessive heat, contact with acids
Incompatible Materials: Strong oxidizers, acids
Hazardous Decomposition Products: Carbon dioxide, sodium oxides under strong heating
Acute Toxicity: LD50 (Oral, Rat) > 8,000 mg/kg, considered non-toxic by ingestion in small amounts
Skin Corrosion/Irritation: Slightly irritating to skin on prolonged contact
Serious Eye Damage/Irritation: Mild eye irritation possible
Respiratory Sensitization: Prolonged inhalation of dust may irritate respiratory tract
Carcinogenicity: Not listed by IARC, NTP, or OSHA as a carcinogen
Reproductive Toxicity: No evidence of adverse effects
Other Information: No cumulative toxicity, not mutagenic or teratogenic based on available data
Ecotoxicity: Low toxicity to aquatic organisms
Persistence and Degradability: Readily biodegradable, decomposes to carbon dioxide and water naturally
Bioaccumulation Potential: Low, does not bioaccumulate in fish or wildlife
Mobility in Soil: High, soluble and mobile in aquatic environments
Aquatic Toxicity: EC50 (Daphnia) > 500 mg/l; fish LC50 > 1000 mg/l; indicative of low risk to surface waters in small amounts
Waste Treatment Methods: Small quantities can be dissolved in water and flushed to drain if local regulations allow
Large Amounts: Dispose of through professional waste disposal contractors
Packaging Disposal: Rinse thoroughly with water before recycling or discarding empty containers
Environmental Precautions: Prevent product from entering storm drains in large amounts
Regulatory Information: Follow applicable municipal, provincial, and federal rules regarding non-hazardous solid waste
UN Number: Not regulated
Proper Shipping Name: Not regulated for transport
Transport Hazard Class: None
Packing Group: Not applicable
Environmental Hazards: Not classified as dangerous for the environment
Special Precautions: Keep package intact, avoid shipment with incompatible materials such as acids
TSCA Inventory: Listed
REACH Registration: Registered
US FDA: Recognized as Generally Recognized As Safe (GRAS) for food use
Canadian DSL: Listed
Labelling: No hazard symbol required; food-grade labeling applies for edible and pharmaceutical applications
Other National Regulations: Complies with EU, US, and Asia-Pacific food and chemical safety rules for specified uses; always consult local regulations for latest requirements
