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Chemical Name: Triisopropyl Phosphite
Synonyms: Phosphorous acid, triisopropyl ester
Molecular Formula: C9H21O3P
CAS Number: 116-17-6
Appearance: Colorless to pale yellow liquid with a distinctive odor
Recommended Use: Used as an intermediate in organic synthesis and as a chemical reagent
Physical Hazards: Flammable liquid and vapor
Health Hazards: Causes respiratory and skin irritation, may damage eyes, harmful if swallowed
Signal Word: Warning
Hazard Statements: Irritating to eyes and respiratory system, can cause burning and discomfort on contact with skin
Precautionary Statements: Avoid inhaling fumes, avoid contact with skin or eyes, use in a well-ventilated area, and wash hands thoroughly after handling
Route of Exposure: Inhalation, skin contact, eye contact, ingestion
Chemical Name: Triisopropyl Phosphite
Concentration: Above 95 percent
Impurities: Trace quantities of related phosphite esters may occur depending on synthesis conditions
Inhalation: Move the affected person to fresh air, monitor breathing, seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, rinse skin with plenty of water using soap if available, seek attention if irritation develops
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, continue rinsing, get medical advice
Ingestion: Do not induce vomiting, rinse mouth, seek prompt medical attention
Suitable Extinguishing Media: Use dry chemical, foam, or carbon dioxide to put out small fires. Water may be used for larger fires but can spread spilled material.
Specific Hazards: Vapors are heavier than air and can travel along the ground to distant sources of ignition, thermal decomposition may produce toxic gases like phosphorus oxides
Protective Equipment for Firefighters: Wear full protective clothing and self-contained breathing apparatus
Personal Precautions: Evacuate unnecessary personnel, ventilate the area, avoid breathing vapors, wear suitable protective gear
Environmental Precautions: Prevent further leakage or spillage where safe, keep from entering drains, surface or groundwater
Cleanup Methods: Absorb with inert material such as sand or earth, collect in suitable containers for disposal, wash area with plenty of water
Handling: Use proper protective equipment, avoid contact with skin and eyes, do not breathe vapors, keep away from sparks and open flames
Storage Conditions: Store in tightly closed containers in a cool, dry, well-ventilated place away from sources of ignition and incompatible materials, such as strong oxidizers
Incompatible Materials: Avoid contact with acids, bases, and oxidizing agents as dangerous reactions can occur
Engineering Controls: Use fume hoods or local exhaust to minimize exposure in workspaces
Personal Protective Equipment: Wear chemical-resistant gloves, safety goggles, and suitable protective clothing
Respiratory Protection: Use appropriate respirators if ventilation is inadequate to avoid inhaling vapors
Hygiene Measures: Wash thoroughly after handling, avoid bringing contaminated clothing home
Physical State: Liquid
Color: Colorless to pale yellow
Odor: Pungent, disagreeable
Boiling Point: 181°C
Flash Point: About 62°C (closed cup)
Solubility: Limited in water, good in most organic solvents
Vapor Pressure: Low at room temperature
Density: Around 0.89 g/cm3 at 20°C
Chemical Stability: Stable under normal conditions if kept away from strong oxidizers and sparks
Reactivity: Reacts with acids, strong bases, and oxidizing agents, can emit toxic fumes if exposed to high temperatures
Hazardous Decomposition Products: Phosphorus oxides, carbon oxides
Conditions to Avoid: Heat, open flames, sources of ignition
Acute Effects: Inhalation may cause sore throat, coughing, and shortness of breath, skin exposure can produce mild to moderate irritation, eye contact may cause burning and damage, ingestion can result in nausea and abdominal pain
Chronic Effects: Repeated or prolonged skin contact can lead to dermatitis, prolonged inhalation risks are not well-studied but should be avoided
Carcinogenicity: Not classified as a carcinogen by major agencies
Sensitization: Not expected to cause skin or respiratory sensitization
Environmental Impact: Harmful to aquatic life with long-lasting effects, avoid release to the environment
Persistence and Degradability: May slowly degrade in water or soil, breakdown products may persist
Bioaccumulation: Tendency to bioaccumulate appears low based on structure and solubility
Mobility in Soil: Moderate volatility, does not bind strongly to soils
Methods of Disposal: Treat as hazardous waste, incinerate in approved facilities, or otherwise dispose according to local regulations
Contaminated Packaging: Triple rinse containers before disposal, avoid reuse of containers
Regulatory Compliance: Follow federal, state, and local guidelines for chemical disposal
UN Number: 3272
Proper Shipping Name: Esters, phosphorus organic, n.o.s. (Triisopropyl Phosphite)
Transport Hazard Class: 3 (flammable liquid)
Packing Group: III
Marine Pollutant: Not classified as a marine pollutant but should be kept from waterways
Special Precautions: Use approved containers, secure tightly to avoid leaks or spills during transit
GHS Classification: Flammable Liquid, Category 3; Eye Irritation, Category 2; Specific Target Organ Toxicity-Single Exposure, Category 3 (respiratory)
SARA Title III: Not listed as an Extremely Hazardous Substance, but reportable as a hazardous chemical
TSCA: Substance listed
EU Classification: Xn (Harmful), R10 (Flammable), R36/37 (Irritating to eyes and respiratory system)
Occupational Safety: No OSHA-specific exposure limit, but handle using recommended controls and PPE
