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Product Name: Trichloroacetic Acid
Synonyms: TCA, Trichloroethanoic acid
Chemical Formula: C2HCl3O2
CAS Number: 76-03-9
Recommended Use: Laboratory reagent, chemical manufacturing, pharmaceutical intermediate
Restrictions: Avoid contact with incompatible materials and unauthorized use
Supplier Details: Manufacturer or distributor contact information available on the product label
Emergency Contact: Poison control center, fire department, or manufacturer emergency line
Classification: Corrosive to skin and eyes, harmful if swallowed, damaging to mucous membranes
Hazard Pictograms: Corrosive symbol, exclamation mark
Signal Word: Danger
Hazard Statements: Causes severe skin burns and eye damage, toxic if inhaled, may cause damage to respiratory tract
Precautionary Statements: Wear protective gear, avoid breathing vapors, use only with proper ventilation, keep away from incompatible substances
Symptoms of Exposure: Burning sensation, blurred vision, respiratory distress, stomach pain, nausea, vomiting
Routes of Exposure: Inhalation, ingestion, skin contact, eye contact
Chemical Name: Trichloroacetic Acid
Chemical Formula: C2HCl3O2
Proportion: 98-100% by weight in pure form
Impurities: Trace amounts of hydrochloric acid, moisture content possible
Molecular Weight: 163.38 g/mol
Inhalation: Move victim to fresh air, keep at rest, seek medical help for breathing difficulties
Skin Contact: Remove contaminated clothing, rinse affected area under running water for at least 15 minutes, seek immediate medical care
Eye Contact: Flush eyes with water for at least 15 minutes holding eyelids open, do not rub eyes, arrange emergency medical attention
Ingestion: Rinse mouth, do not induce vomiting, seek immediate medical assistance
Immediate Actions: Remove to safe area, monitor vital signs, provide oxygen if needed
Special Advice: Emergency medical responders should use full personal protection and avoid direct exposure
Suitable Extinguishing Media: Use foam, dry chemical or CO2 for small fires; use water spray to cool containers exposed to fire
Unsuitable Media: Avoid high-pressure water streams that may spread material
Specific Hazards: May release toxic gases such as hydrogen chloride, phosgene, and carbon monoxide
Protective Equipment for Firefighters: Self-contained breathing apparatus, chemical resistant protective gear
Special Precautions: Approach from upwind, evacuate area, prevent runoff from entering drains or watercourses
Explosion Sensitivity: Non-explosive, but containers may rupture if heated in fire
Emergency Procedures: Isolate hazard area, keep unauthorized personnel away
Personal Precautions: Evacuate unnecessary personnel, wear chemical resistant clothing, goggles, gloves, and suitable respirator
Environmental Precautions: Prevent release into water bodies, soil, and drains
Spill Cleanup Methods: Absorb with inert material such as sand or earth, place in suitable waste container, wash area with copious amounts of water
Special Instructions: Neutralize residue with alkaline material like sodium bicarbonate
Disposal of Waste: Follow all federal, state, and local regulations
Precautions: Avoid contact with skin, eyes, and clothing, do not breathe vapors or dust, ensure good ventilation
Safe Handling Methods: Use only in chemical fume hood or well-ventilated space, handle with appropriate PPE
Storage Requirements: Store away from heat sources in corrosion-resistant containers, keep container tightly closed
Incompatible Materials: Strong bases, oxidizers, reducing agents, active metals
Storage Temperature: Store at ambient temperature in dry, protected location
Other Storage Instructions: Label containers clearly, keep away from incompatible chemicals and foodstuffs
Occupational Exposure Limits: ACGIH TLV: 0.5 ppm (skin), OSHA PEL not established
Engineering Controls: Use chemical fume hood, local exhaust systems, emergency eye wash stations and safety showers available nearby
Personal Protective Equipment: Chemical-resistant gloves (nitrile, PVC), safety goggles, lab coat or apron, long pants, closed shoes, face shield for splash risk
Respiratory Protection: NIOSH-approved respirator if exposure limits are exceeded or if ventilation is inadequate
Hygiene Measures: Wash hands and face after handling, do not eat, drink or smoke during use
Appearance: White crystalline solid or colorless solution
Odor: Pungent, sharp, acidic
Melting Point: 54 °C (129.2 °F)
Boiling Point: 196 °C (384.8 °F)
Density: 1.63 g/cm³
pH (aqueous solution): Below 2
Solubility: Very soluble in water, ethanol, ether
Vapor Pressure: 0.2 mmHg at 20 °C
Flash Point: Not applicable (non-flammable)
Partition Coefficient (n-octanol/water): log Kow = 1.33
Evaporation Rate: Not measurable at ambient temperature
Chemical Stability: Stable at room temperature under recommended storage conditions
Potential for Hazardous Reactions: Reacts vigorously with bases, ammonia, amines, metal powders
Conditions to Avoid: Moisture, heat, open flame, exposure to incompatible materials
Hazardous Decomposition Products: Hydrogen chloride, carbon monoxide, carbon dioxide, chlorine gas
Polymerization: Not known to polymerize
Other Incompatibilities: Alkali metals, strong reducing agents may cause violent reactions
Acute Toxicity: Oral LD50 (rat): 3,320 mg/kg; Inhalation LC50 and Dermal LD50 data limited
Skin Corrosion/Irritation: Causes severe burns and ulceration
Serious Eye Damage/Irritation: Causes lasting eye injury, possible permanent vision loss
Respiratory Sensitization: May cause burning sensation, cough, sore throat, respiratory distress
Ingestion Effects: Can cause gastrointestinal damage, abdominal pain, vomiting, diarrhea
Chronic Effects: Long-term skin contact may result in dermatitis, scarring, sensitization
Carcinogenicity: No indication of carcinogenicity from current studies
Mutagenicity and Reproductive Toxicity: No mutagenic or reproductive hazards documented with normal laboratory handling
Target Organs: Skin, eyes, mucous membranes, respiratory tract
Ecotoxicity: Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Persistence and Degradability: Tends to hydrolyze and biodegrade in soil and water
Bioaccumulative Potential: Low to moderate potential for bioaccumulation in aquatic organisms
Mobility: Highly mobile in water, may contaminate groundwater
Other Adverse Effects: Toxic to plants and animals at high concentrations
Environmental Precautions: Avoid release into environment, comply with all discharge regulations
Waste Treatment Methods: Dispose through licensed hazardous waste contractor, never pour into drains or watercourses
Container Disposal: Rinse empty containers with caution, puncture and dispose of according to local regulations
Recycling: Not recommended due to contamination risk
Special Precautions: Label waste with proper hazard codes, store waste in corrosion-resistant containers until disposal
UN Number: UN 2564
Proper Shipping Name: Trichloroacetic Acid, Solid or Solution
Transport Hazard Class: 8 (Corrosive)
Packing Group: II (Medium Danger)
Label Requirements: Corrosive material label
Marine Pollutant: Yes
Special Transport Precautions: Keep container upright and securely closed, avoid rough handling, carry in accordance with federal and local transportation rules
Transport Documentation: Complete shipping paperwork, including emergency contacts
OSHA: Classified as hazardous, full compliance with safety standard required
TSCA: Listed on United States Toxic Substances Control Act Inventory
SARA Title III: Reportable under Section 313 for toxic chemical release
EPA: Regulated as an environmental hazard, report any release over reportable quantity
WHMIS Classification (Canada): D1B (Toxic), E (Corrosive Material)
REACH (EU): Registered substance, subject to manufacturer’s requirements
Other Global Lists: Compliant with main international chemical safety regulations
Label Requirements: Product containers must carry proper hazard symbols, warning statements, and first aid instructions
