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Material Safety Data Sheet (MSDS) for Titanium (IV) Oxide

Identification

Product Name: Titanium (IV) Oxide, also known as Titanium Dioxide
Chemical Formula: TiO2
Synonyms: Rutile, Anatase
CAS Number: 13463-67-7
Recommended Use: Used widely in paints, coatings, plastics, paper, sunscreen, food coloring, and cosmetics
Manufacturer/Supplier: Contact information for the chemical’s producer or distributor needs placement here for emergency or technical questions
Emergency Contact: Include a local or national poison center and manufacturer emergency number for quick response

Hazard Identification

Classification: Not classified under GHS for acute toxicity, skin irritation, or eye irritation; may cause respiratory irritation if dust is inhaled frequently over long periods
Main Hazards: Chronic inhalation of dust might increase risk of lung effects; listed by IARC as possibly carcinogenic via inhalation of ultrafine particles; no acute dermal, oral, or ocular hazards with normal use
Signal Word: Warning
Hazard Statements: Dust may cause mild irritation of respiratory tract, eyes, or skin; excessive concentrations in air could impact breathing
Precautionary Statements: Avoid breathing dust; handle in well-ventilated areas; wash thoroughly after use; avoid release to the environment

Composition / Information on Ingredients

Main Component: Titanium Dioxide
Concentration: ≥ 98%
Impurities: May contain traces of iron oxide, silica, or alumina depending on manufacturing process
Chemical Family: Inorganic oxide

First Aid Measures

Inhalation: Move person into fresh air as soon as possible; seek medical attention for persistent cough or discomfort
Eye Contact: Rinse cautiously under running water for at least 15 minutes; remove contact lenses if present and easy to do; medical advice may help for lingering irritation
Skin Contact: Wash affected area with soap and water; use lotion to relieve dryness if skin feels tight or dusty
Ingestion: Rinse mouth with water; do not induce vomiting; call a doctor if large quantities swallowed or symptoms persist
Note to Physicians: Treat symptomatically based on observations; no antidote required but monitor for respiratory symptoms

Fire-Fighting Measures

Suitable Extinguishing Media: Use dry chemical, foam, carbon dioxide, or water spray for surrounding materials; titanium dioxide itself does not burn but may be present in combustibles
Hazardous Combustion Products: Titanium dioxide is stable in fires but fine particulates might aggravate dust explosions in special cases
Protective Equipment: Firefighters should wear self-contained breathing apparatus and protective gear to prevent skin and eye contact with dust
Special Procedures: Avoid breathing dust from fire residue; contain water runoff to avoid environmental spread

Accidental Release Measures

Personal Precautions: Wear appropriate dust masks, gloves, goggles; restrict access to spill area
Environmental Precautions: Avoid releasing large amounts into sewers, drains, or natural waters
Cleanup Procedures: Gently sweep, shovel, or vacuum up spilled material without generating dust clouds; place in sealed containers for disposal; wash affected area with water
Decontamination: Clean tools and equipment thoroughly

Handling and Storage

Handling: Use only with adequate ventilation; minimize dust generation; handle with care to prevent spills or dispersal
Storage: Store in tightly sealed containers in dry, cool, well-ventilated spaces; avoid contact with incompatible chemicals such as strong acids or reducing agents
Hygiene Practices: Wash hands and exposed body thoroughly after handling; do not eat, drink, or smoke in work areas; keep away from children and pets

Exposure Controls and Personal Protection

Occupational Exposure Limits: OSHA PEL (US): 15 mg/m³ total dust, 5 mg/m³ respirable fraction; ACGIH TLV: 10 mg/m³ total dust
Engineering Controls: Use local exhaust ventilation to keep airborne levels below recommended limits; provide eye wash stations
Personal Protective Equipment: Safety goggles, gloves, dust masks or respirators certified for particulates (such as NIOSH N95); long sleeves and pants for extended exposure

Physical and Chemical Properties

Appearance: White, odorless powder
Odor: None
pH: Neutral in water suspension
Melting Point: 1,843°C (3,349.4°F)
Boiling Point: Not applicable (decomposes before boiling)
Solubility: Insoluble in water and organic solvents
Density: 3.9–4.2 g/cm³
Vapor Pressure: Not applicable
Particle Size: Varies, commonly in micrometer or nanometer form
Flash Point: Not flammable

Stability and Reactivity

Stability: Chemically stable under most conditions
Incompatibility: Strong acids, strong reducing agents (e.g., aluminum powder and magnesium powder under certain conditions)
Hazardous Decomposition: No hazardous decomposition expected in normal use
Polymerization: Will not occur

Toxicological Information

Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Acute Toxicity: Very low toxicity by oral, dermal, or inhalation exposure
Chronic Effects: Long-term exposure to airborne dust may affect lungs; IARC lists as Group 2B (possible human carcinogen for inhaled dust)
Symptoms: Mild irritation of eyes, nose, throat with high dust concentrations
Carcinogenicity: No increase in cancer risk observed in studies of workers exposed to pigment grade form; ultrafine or nano-sized forms under investigation for risk
Other Data: Not mutagenic, not teratogenic, not known to affect reproduction

Ecological Information

Aquatic Toxicity: Low toxicity to aquatic life due to poor solubility; heavy releases can cloud water and decrease light penetration, possibly affecting aquatic plants and animals
Persistence and Degradability: Remains stable and does not break down chemically in environment
Bioaccumulation: Not expected to build up in food chains
Mobility: Due to insolubility, tends to settle out in sediment
Other Effects: No significant environmental hazards identified from normal use or disposal

Disposal Considerations

Waste Treatment Methods: Dispose of according to local, state, and federal regulations; landfill in sealed containers
Precautions: Prevent scattering of dust during disposal; avoid dumping into water courses or sewers
Recycling: Where feasible and appropriate, recycling or re-processing options may exist for industrial quantities
Special Notes: Product is non-hazardous waste but containers should be rinsed thoroughly and recycled or disposed in accordance with regulations

Transport Information

UN Number: Not regulated under international transport rules
Transport Hazard Class: Not classified as a hazardous material
Packing Group: Not assigned
Shipping Name: Titanium Dioxide
Special Precautions: Prevent broken packaging or excessive dust generation during transit; keep dry during shipment

Regulatory Information

U.S. Regulations: Listed on TSCA Inventory; OSHA hazardous only as a dust under the Hazard Communication Standard; SARA Title III, Section 313 reporting not required
EU Regulations: Complies with REACH; classified as not hazardous under EU CLP, with caution for long-term inhalation
Labeling Requirements: Standard workplace labelling applies; hazard symbols for dust inhalation recommended in risk situations
International Listings: Included in inventories for Canada (DSL/NDSL), Australia (AICS), Japan (ENCS), and other countries; consult specific national guidelines for workplace limits