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Product Name: Thiamine Hydrochloride
Chemical Formula: C12H17ClN4OS·HCl
Synonyms: Vitamin B1 hydrochloride, Thiamin HCl
CAS Number: 67-03-8
Recommended Use: Pharmaceutical ingredient, dietary supplement, food fortifier
Supplier Information: Reach out to the direct producer or authorized distributor for emergency contacts and details
Emergency Phone Number: Provided by local supplier or label documentation
GHS Classification: Not classified as dangerous according to Regulation (EC) No 1272/2008
Signal Word: None required
Hazard Statements: May cause mild skin and eye irritation in sensitive people
Precautionary Statements: Avoid breathing dust, wash hands thoroughly after handling, wear basic protective equipment
Potential Health Effects: Inhalation may cause respiratory discomfort, ingestion of large amounts could result in mild gastrointestinal upset, repeated skin exposure might dry or irritate sensitive skin
Chemical Name: Thiamine Hydrochloride
Concentration: 98-102% purity
Impurities: Small traces of related Vitamin B1 derivatives and manufacturing residues considered non-hazardous
Additional Components: May contain less than 2% moisture as water or bound solvent from storage conditions
Inhalation: Remove from exposure, breathe fresh air, seek medical attention if symptoms develop or persist
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, continue rinsing, seek medical help if discomfort continues
Skin Contact: Wash with plenty of soap and water, remove contaminated clothing, medical guidance needed if irritation continues
Ingestion: Rinse mouth with water, drink small amounts of water if conscious, avoid inducing vomiting unless directed by medical personnel, consult a doctor for significant amounts
Extinguishing Media: Use dry chemical, CO2, water spray or foam
Hazardous Combustion Products: Carbon oxides, nitrogen oxides, hydrogen chloride gas, sulfur oxides created if burnt
Fire Fighting Instructions: Wear full protective gear including self-contained breathing apparatus, avoid exposure to fumes
Additional Precautions: Do not allow fire run-off to reach drains or watercourses, control contaminated fire water for safe disposal
Personal Precautions: Wear suitable personal protective equipment such as gloves, goggles, dust mask
Spill Procedures: Sweep up avoid creating dust, transfer into suitable containers for disposal, ventilate area
Environmental Precautions: Prevent further leakage, do not let product enter drains
Clean-up Methods: Use water dampened cloth to finish area, dispose of absorbents and solid waste according to regulations
Handling: Handle in well-ventilated areas, minimize dust generation, avoid contact with skin and eyes, wash thoroughly after handling
Storage: Store in tightly closed container, away from light, heat, and moisture, keep in a cool, dry place
Incompatible Materials: Strong oxidizers, strong acids, avoid contact with these for stability reasons
Additional Storage Advice: Use original container whenever possible, label containers, practice regular inventory rotation for stock
Engineering Controls: Use local exhaust ventilation or work in fume hood if available
Respiratory Protection: Dust mask or respirator if airborne concentrations become significant
Skin Protection: Wear protective gloves, long-sleeved clothing
Eye Protection: Chemical safety glasses with side shields
Hygiene Measures: Wash hands before eating, drinking or smoking, avoid hand-to-face contact during handling
Appearance: White to pale yellow crystalline powder
Odor: Nearly odorless, faint yeast-like smell for some individuals
pH (5% solution): 2.7 – 3.4
Melting Point: Decomposes above ~248°C
Solubility in Water: Highly soluble; >100 g/L at 20°C
Solubility in Other Solvents: Slightly soluble in alcohol, almost insoluble in chloroform and ether
Boiling Point: Not applicable due to decomposition before boiling
Flash Point: Not established for solid organic compound
Relative Density: 1.70 (water = 1)
Partition Coefficient: Log Pow -2.57 estimated
Vapor Pressure: Negligible at room temperature
Other Properties: Stable under recommended storage conditions, light and humidity sensitive
Chemical Stability: Stable when stored in sealed containers out of direct sunlight and moisture
Incompatible Materials: Reactive with strong oxidizing agents, powerful acids
Decomposition Products: Emits nitrogen oxides, carbon oxides, sulfur oxides, hydrogen chloride when heated or burned
Hazardous Reactions: No dangerous polymerization, but can degrade with prolonged exposure to sunlight or high temperatures
Conditions to Avoid: Excess moisture, heat, open flame, long exposure to air
Acute Toxicity: Oral LD50 in rats estimated at > 5,000 mg/kg, low acute toxicity
Skin Contact: No sensitization or significant irritation in standard studies
Eye Contact: May cause watering or mild irritation in sensitive individuals
Inhalation Exposure: Inhalation of dust may irritate respiratory tract, particularly in those with pre-existing lung conditions
Chronic Effects: No evidence of carcinogenicity, mutagenicity, or reproductive toxicity from available data
Additional Symptoms: Large oral doses may cause mild upset stomach, restlessness, or hypersensitivity in rare cases
Medical Conditions Aggravated: Individuals hypersensitive to thiamine should avoid high exposures
Environmental Fate: Readily biodegradable in soil and water, low potential for bioaccumulation
Ecotoxicity: Not classified as hazardous to aquatic or terrestrial organisms at typical use concentrations
Mobility: High solubility in water increases mobility through soil if large spills occur
Persistence: Breaks down naturally under environmental conditions, rapid microbial degradation reported
Aquatic Toxicity: No demonstrated adverse effects to aquatic species at expected discharge levels
Other Environmental Hazards: Released product should be contained to prevent waste and minimize unnecessary introduction to waterways
Waste Disposal Method: Dispose of through chemical waste collection programs or authorized waste disposal contractors
Unused Product: Return surplus product to original supplier or dispose as pharmaceutical waste
Contaminated Packaging: Rinse containers thoroughly before disposal, follow local recycling or disposal regulations
Regulatory Disposal Requirements: Consult local, regional, and national waste disposal authorities for specific instructions
UN Number: Not regulated for transport under UN, IMO, IATA or DOT regulations
Proper Shipping Name: Not applicable, product poses no special transport hazard
Transport Hazard Class: Not assigned
Packing Group: Not assigned
Special Precautions: Keep container tightly closed and protected from moisture, transport in original or compatible sealed packaging
EU Classification: No hazard labeling required under EC directives or corresponding regulations
TSCA Status (USA): Listed
EINECS (EU): Listed (200-641-8)
REACH Registration: Exempt: considered a vitamin/food additive
Other Regulations: Complies with relevant sections of Food Chemical Codex, USP, EP requirements for pharmaceutical and food-grade materials
Workplace Regulation: Provide basic safety training for product use, ensure access to MSDS on-site for reference
Labeling Requirements: Follow applicable food, pharmaceutical, or workplace safety labeling instructions in your country or region
