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Product Name: Tetrabutylammonium Bisulfate
Synonyms: N,N,N-Tributylbutan-1-aminium hydrogen sulfate
Chemical Formula: C16H37NO4S
CAS Number: 32503-27-8
Relevant Uses: Phase transfer catalyst, organic synthesis, analytical reagent
Supplier: Listed on product label with full address and emergency phone number for chemical incidents
Hazard Classification: Classified as irritating to the skin and eyes, may cause respiratory irritation, does not carry acute toxicity hazards under normal handling but presents risks of skin, eye, and mucous membrane irritation
Symbol: Exclamation mark (GHS07)
Signal Word: Warning
Hazard Statements: Causes skin and serious eye irritation, may cause respiratory irritation, harmful if swallowed in large quantities
Precautionary Statements: Avoid contact with skin and eyes, do not breathe dust or vapors, use only outdoors or in a well-ventilated area, wash hands and exposed skin thoroughly after handling
Chemical Name: Tetrabutylammonium Bisulfate
Purity: ≥98%
CAS Number: 32503-27-8
EC Number: 251-078-4
Impurities: No significant impurities contributing to the hazard classification under normal circumstances
General Advice: Move to fresh air if inhaled, call a doctor if symptoms develop
Inhalation: Remove victim to fresh air, keep warm and at rest, seek medical attention if coughing or discomfort persists
Skin Contact: Remove contaminated clothing, rinse skin with water and mild soap for at least 15 minutes, seek medical help if irritation continues
Eye Contact: Rinse eyes gently with clean water for a minimum of 15 minutes, hold eyelids apart, and get medical assistance if irritation occurs
Ingestion: Do not induce vomiting, rinse mouth with water, seek immediate medical help if feeling unwell or after swallowing
Most Important Symptoms: Irritation, redness, coughing, possible nausea after ingestion
Suitable Extinguishing Media: Use water spray, foam, dry chemical, or carbon dioxide
Unsuitable Media: High-pressure water streams may spread product
Special Hazards: Decomposition releases hazardous vapors such as nitrogen oxides, sulfur oxides, carbon monoxide, possible noxious organic fumes under fire conditions
Protective Equipment for Firefighters: Self-contained breathing apparatus, chemical-resistant suit, and goggles
Advice for Firefighters: Move containers away from fire area if possible without risk, use water spray to cool unopened containers exposed to fire
Personal Precautions: Wear gloves, safety goggles, lab coat, and appropriate respirator to protect from dust inhalation
Environmental Precautions: Prevent spillage from reaching drains or waterways, contain spillage using absorbent materials and non-combustible barriers
Clean-Up Methods: Scoop up spilled material with non-sparking tools, place in fully labeled container for proper disposal, wash contaminated area with water and detergent
Reference to Other Sections: See sections on personal protection and disposal for further advice on handling contaminated material
Handling: Use only in well-ventilated places, avoid contact with skin, eyes, and clothing, do not breathe dust, avoid splashes and use local exhaust ventilation if available, keep containers tightly closed and labeled
Storage: Keep in a dry, cool, well-ventilated area away from strong oxidizers, acids, and bases, store in original chemical-resistant containers out of direct sunlight and away from sources of ignition, segregate from incompatible materials
Hygiene Measures: Do not eat, drink, or smoke while handling, wash hands thoroughly after use, remove and clean contaminated clothing before reuse
Control Parameters: No occupational exposure limits set by OSHA, ACGIH, or NIOSH for this compound
Engineering Controls: Work with chemical fume hood or other effective local exhaust system, install eyewash stations and safety showers in the work area
Personal Protective Equipment: Nitrile or neoprene gloves, lab coat or coveralls, closed-toe shoes, chemical splash goggles or face shield, certified respirator for dust if ventilation is insufficient
Environmental Measures: Use engineering control measures to prevent exposure above allowable limits and limit release to the environment
Physical State: Solid, crystalline or powder
Color: White to off-white
Odor: Faint to odorless
Molecular Weight: 339.53 g/mol
Melting Point: 120–130°C (varies slightly by grade)
Density: Approximately 0.95 g/cm³ at 20°C
Solubility: Soluble in water, ethanol, and some organic solvents
Boiling Point: Decomposes before boiling
pH (in water): ~4.0–5.0 (1% solution)
Vapor Pressure: Not measurable at room temperature
Partition Coefficient: No significant data for octanol/water
Chemical Stability: Stable under recommended storage conditions, can degrade on exposure to strong heat or acids
Reactivity: Reacts with strong oxidizing agents, strong bases, and strong acids
Hazardous Decomposition Products: Nitrogen oxides, sulfur oxides, carbon monoxide, and possibly corrosive vapors formed at high temperatures
Conditions to Avoid: Excessive heat, open flames, moisture, direct sunlight
Incompatible Materials: Strong oxidizing agents, strong acids, strong bases
Routes of Exposure: Inhalation, skin or eye contact, ingestion
Acute Toxicity: Low oral and dermal toxicity; ingestion may cause gastrointestinal distress, headache, or dizziness
Skin Corrosion/Irritation: Causes moderate to severe irritation, redness, possible swelling
Serious Eye Damage/Irritation: Risk of severe irritation, pain, watering, blurred vision
Respiratory Sensitization: Inhalation of dust or fine particles may irritate respiratory tract, causing cough or shortness of breath
Chronic Effects: Long-term exposure not well studied, avoid repeated contact
Carcinogenicity: No listed carcinogens per IARC, NTP, OSHA
Other Information: No evidence of mutagenicity or reproductive toxicity in available public data
Ecotoxicity: Not classified as highly toxic to aquatic organisms, but large spills may affect water pH and aquatic microflora, disrupt natural biological systems if released in excess
Persistence and Degradability: Degrades slowly in the environment, not expected to accumulate under normal usage, portions of the molecule may persist in sediment
Bioaccumulative Potential: Not significantly bioaccumulative, based on molecular size and water solubility
Mobility in Soil: Soluble, may migrate into waterways if improperly disposed
Other Adverse Effects: Minimize accidental release to aquatic and soil environments, follow local wastewater requirements
Waste Treatment Methods: Dispose of in accordance with local, regional, and national regulations, process as hazardous chemical waste if mixed with solvents or reagents
Container Disposal: Rinse thoroughly, triple rinse for containers, render unusable, follow proper procedures for hazardous waste containers
Incineration: Only in permitted chemical incineration facilities with scrubbers for acidic gases, do not dispose of in household waste
Environmental Precautions: Do not allow to enter drains, surface water, or soil, report to authorities if contamination occurs
UN Number: Not regulated under most international transport regulations (IATA, IMDG, DOT) in small quantities
Proper Shipping Name: Not classified as a dangerous good
Transport Hazard Classes: None assigned
Packing Group: None assigned
Special Precautions: Avoid exposure to moisture during transport, ensure containers are tightly sealed and properly labeled, segregate from incompatible materials during shipment
Labelling Requirements: Conforms to GHS, OSHA HCS, and international chemical labeling rules
SARA Title III: Not subject to reporting requirements
TSCA Inventory: Listed
REACH Compliance: Substance registered or exempt under applicable REACH provisions for imported volumes
WHMIS Classification (Canada): Classes D2B (toxic, eye and skin irritant)
Other Regulations: See state, local, and international regulations for any additional requirements concerning use, handling, or disposal
