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Product Name: 2-Aminoterephthalic Acid
CAS Number: 2942-59-8
Chemical Formula: C8H7NO4
Synonyms: 2-Aminobenzene-1,4-dicarboxylic acid
Recommended Use: Laboratory chemicals, synthesis of metal-organic frameworks, organic synthesis
Supplier Information: Consult local distributor
Emergency Contact: Refer to local regulations or in-house protocol
Manufacturer: Refer to label or purchasing documentation for manufacturer details
Classification: Eye irritation (Category 2A), Skin irritation (Category 2), Specific target organ toxicity - single exposure (Category 3)
Signal Word: Warning
Hazard Statements: Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: Avoid breathing dust. Wear protective gloves, protective clothing, and eye protection. Wash hands thoroughly after handling.
Potential Health Effects: Irritation to eyes, skin, and respiratory system. Prolonged contact or exposure may intensify symptoms.
GHS Pictograms: Exclamation mark
Routes of Entry: Inhalation, skin contact, eye contact, ingestion
Target Organs: Eyes, skin, respiratory system
Chemical Name: 2-Aminoterephthalic Acid
CAS Number: 2942-59-8
Concentration: 100% by weight
Impurities/Additives: No major hazardous impurities listed; purity may vary by supplier, impurities typically below 1%
Inhalation: Remove to fresh air. Seek medical attention if irritation, coughing, or difficulty breathing continues.
Skin Contact: Remove contaminated clothing. Wash affected area thoroughly with soap and water for several minutes. Seek medical advice if symptoms persist or develop.
Eye Contact: Rinse cautiously with water for at least 15 minutes, lifting upper and lower eyelids occasionally. Remove contact lenses if present and easy to do. Continue rinsing and seek immediate medical advice.
Ingestion: Rinse mouth with water. Do not induce vomiting unless directed by medical personnel. Seek medical attention if discomfort occurs.
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Unsuitable Extinguishing Media: Avoid using a direct water jet since it may spread burning material
Specific Hazards: Combustion may produce irritant or toxic gases (nitrogen oxides, carbon oxides)
Protective Equipment: Firefighters require self-contained breathing apparatus and full protective gear
Special Procedures: Cool containers exposed to fire with water spray to prevent overheating and rupture
Hazardous Decomposition: Nitrogen oxides, carbon monoxide, carbon dioxide
Personal Precautions: Evacuate area. Avoid dust formation and inhalation. Wear appropriate protective equipment including gloves, eye protection, and respiratory mask.
Environmental Precautions: Prevent further leakage or spillage if safe. Do not let chemical enter drains or watercourses.
Cleanup Methods: Sweep up, collect, and place in a suitable container for disposal according to local regulations. Dispose of contaminated cleaning materials in a similar fashion. Ventilate area thoroughly.
Handling Spills: Use non-sparking tools. Avoid stirring up dust. Wash spill area once pickup is complete.
Handling: Use with adequate ventilation. Prevent dust formation. Avoid contact with skin, eyes, and clothing. Do not inhale dust or vapors. Wear appropriate protective gear at all points of transfer and use.
Storage: Store in a tightly closed container. Keep in a cool, dry, well-ventilated area away from incompatible substances such as strong oxidizers. Protect from moisture and direct sunlight. Label storage container with product identity and hazard warnings.
Special Handling Instructions: Use only with proper training and awareness of chemical hazards. Keep containers upright and secure to minimize spillage risk.
Occupational Exposure Limits: No specific exposure limits established for 2-Aminoterephthalic Acid by OSHA, ACGIH, or NIOSH
Engineering Controls: Use local exhaust or general dilution ventilation to control airborne dust and vapors. Safety showers and eye wash stations recommended in work area.
Personal Protective Equipment:
- Respiratory Protection: Use an approved dust mask or respirator when exposure may exceed recommended limits or during bulk handling
- Skin Protection: Wear chemical-resistant gloves and lab coat
- Eye Protection: Chemical safety goggles or face shield required
- Hygiene Measures: Wash hands after handling. Remove and wash contaminated clothing before reuse. Avoid eating, drinking, or smoking when using this compound.
Appearance: Pale yellow to off-white crystalline powder
Odor: Odorless or faint organic odor
pH: Slightly acidic (as 0.1 M solution)
Melting Point: 350–355°C (decomposes)
Boiling Point: Not applicable (decomposes before boiling)
Flash Point: Not determined
Flammability: Not classified as flammable
Vapor Pressure: Negligible at ambient conditions
Solubility: Slightly soluble in water, more soluble in hot water; insoluble in most organic solvents
Relative Density: 1.6 g/cm³
Molecular Weight: 181.15 g/mol
Partition Coefficient (Log Kow): Data not available
Auto-Ignition Temperature: Data not available
Explosive Properties: Not known to be explosive
Oxidizing Properties: Not identified as an oxidizer
Chemical Stability: Stable under recommended storage conditions. Material will decompose above melting point.
Reactivity: Not considered reactive under standard conditions, non-reactive toward most container materials
Conditions to Avoid: Excessive heat, moisture, sources of ignition, incompatible materials
Incompatible Materials: Strong bases, strong oxidizing agents, strong reducing agents
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide
Polymerization: No reported hazardous polymerization
Acute Toxicity: Limited data available; oral LD50 (rat) > 2000 mg/kg (expected low acute toxicity)
Skin Corrosion/Irritation: May cause skin irritation in sensitive individuals. Redness or itching possible on contact.
Serious Eye Damage/Irritation: Contact can cause moderate to severe eye irritation, watering, or redness
Respiratory Sensitization: Dust inhalation may provoke respiratory irritation, coughing, or sore throat
Skin Sensitization: Not classified as skin sensitizer; rare cases of allergic reaction possible
Germ Cell Mutagenicity: No significant evidence of mutagenic risk based on available data
Carcinogenicity: Not listed by IARC, NTP, or OSHA as a known carcinogen
Reproductive Toxicity: No adverse reproductive effects reported in available studies
Specific Target Organ Toxicity: Respiratory tract irritation possible at high concentrations
Aspiration Hazard: Not considered an aspiration hazard
Symptoms of Overexposure: Eye and skin discomfort, respiratory tract irritation, mild gastrointestinal symptoms if ingested
Ecotoxicity: Data scarce for aquatic and terrestrial toxicity; structurally-related compounds show low to moderate toxicity for aquatic life
Persistence and Degradability: Likely to biodegrade slowly in the environment; persistence is moderate
Bioaccumulation Potential: Low expected based on water solubility and molecular structure
Mobility in Soil: Moderate mobility expected; some potential for leaching under certain conditions
Other Adverse Effects: No evidence of significant ozone depletion, global warming, or endocrine disruption potential. Avoid uncontrolled release into natural ecosystems.
Waste Disposal Methods: Dispose in a chemical waste facility or as hazardous waste according to local, regional and national regulations. Chemical incineration or landfill at approved site.
Contaminated Packaging: Containers rinsed and emptied completely may be recycled or disposed per local laws. Contaminated packaging must be handled in the same way as the chemical itself.
Special Precautions: Avoid release into waterways and sewage. Do not dispose of into household garbage.
UN Number: Not classified as a dangerous good by major transport regulations (ADR, IATA, IMDG)
Proper Shipping Name: Not regulated for transport
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Environmental Hazards: Not classified as a marine pollutant
Special Precautions for Transport: Secure containers to prevent tipping. Label shipments clearly if transported within laboratory or industrial supply chain.
OSHA Hazard Communication: Substance classified as hazardous under OSHA HazCom standard
TSCA Status: Listed in the TSCA inventory
REACH Registration: Check availability with appropriate importer or European supplier
Canada (DSL/NDSL): Substance covered by Canadian regulations; contact for details
Other Regulation: Not listed as a controlled or narcotic substance. No significant SARA Title III, or CERCLA reporting thresholds at standard volumes for academic or industry uses.
Labeling Requirements: Appropriate hazard labeling required under workplace safety standards. Training required for handling this specialty chemical according to local regulations.
