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Terbutaline sulfate entered the medical scene in the late 1960s, following decades of growing interest in selective beta-2 adrenergic agonists. At that point, asthma management and relief from bronchospasm still involved drugs with significant side effects, often linked to poor receptor selectivity. Swedish researchers working for Astra focused on the structure-activity relationships of catecholamines, spotting how sidestepping the heart’s beta-1 receptors could enable better targeting of lung tissue and maternal smooth muscle. Terbutaline’s story tracks the broader push for precision pharmacology coming out of the post-war chemistry boom. As patents rolled out and clinical trials published their results, more clinicians gained trust in terbutaline’s shorter onset and longer bronchodilation, compared to the older agents, especially for acute attacks. This shift didn’t change overnight, though—the field balanced early excitement with caution as reports trickled in about off-label uses, particularly in managing preterm labor.
Terbutaline sulfate shows up in pharmacies as tablets, injections, and inhalers. You’ll notice the oral form comes in both 2.5 mg and 5 mg strengths, while the injectable solution delivers the drug at 1 mg/mL for acute situations in hospitals. Inhalers featuring terbutaline sulfate, particularly popular in Europe, typically dish out dosed powder or aerosol for rapid lung delivery. What sets it apart is a reputation for potent, selective muscle relaxation in airways, paired with a relatively lower risk of racing heart compared to some peers. Across continents, national formularies keep terbutaline on their lists for both chronic asthma management and sudden bronchospasm relief. Since the late 1970s, its use in suppressing preterm labor sparked debate and guidance revisions, making clinicians weigh short-term benefits against cardiovascular and metabolic risks.
On the bench, terbutaline sulfate appears as a white, odorless powder with a bitter taste. The molecule boasts a molecular formula of C12H19NO3•H2SO4, producing a weight of 403.46 g/mol. As a sulfate salt, it gains greater water solubility than the free base, supporting its varied dosage forms. Terbutaline’s structure features a substituted phenethylamine skeleton: two hydroxyl groups on the aromatic ring and a tert-butyl group on the amine—features which turn up in the lab’s signature spectra and also tie directly into the bronchodilator action. This bulky side group blocks monoamine oxidase metabolism and helps the molecule stick primarily to beta-2 receptors, keeping systemic effects in check. In solution, the melting point runs around 148°C (with decomposition) and the powder holds up under light and modest temperature changes, giving manufacturers a measure of stability in packaging and transport.
Quality standards for terbutaline sulfate follow global pharmacopoeias, each setting tight limits on impurities, water content, and assay values. For instance, USP and EP requirements demand assay ranges of 98.5–101.5% for the labeled content. The drug must also clear rigorous testing for related substances, residue on ignition, and loss on drying. Labels must clearly indicate dosage strength, lot number, manufacturer information, and strict storage instructions—typically “store below 25°C and protect from light.” Injectable products require color-coding and tamper-evident packaging. As safety data updates roll out, package inserts include warnings about cardiovascular risks, interactions with other sympathomimetics, and specialized notes for pregnancy use. Some countries enforce boxed warnings on OB use, spotlighting the risks of extended infusions in preterm labor, aiming to keep clinicians fully informed at the point of care.
Pharmaceutical manufacturers rely on multi-step organic synthesis to produce terbutaline. The classic route starts from 3,5-dihydroxyacetophenone, subjecting it to reductive amination with tert-butylamine, then O-methylation and protective group manipulations, before forming the sulfate salt via neutralization. Each intermediate stage gets cleaned up with selective crystallization and solvent partitioning to control impurity profiles. After final purification, the base compound is converted to a sulfate salt using concentrated sulfuric acid, and the isolated product dries under vacuum. Scaling this process up to industrial quantities took plenty of tweaking through the 1970s and 1980s, with improvements in solvent recycling and temperature control slashing costs and waste. High-purity output matters here—not just for regulatory approval, but also for keeping batch-to-batch efficacy and safety up to par.
Terbutaline’s chemical character invites selective modifications—adding or changing the tert-butyl group on the amine, for instance, leads to closely related beta-agonists like salbutamol. Chemists have investigated analogs to probe differences in receptor binding and metabolic stability, shaping several “second-generation” bronchodilators. The aromatic hydroxyls stand out as reactive sites: etherification or esterification attempts usually run into trouble by undercutting beta-2 selectivity, so most pharmaceutical tweaks stick to protecting-group strategies for synthesis. Analytical chemists depend on HPLC and capillary electrophoresis to check for breakdown products and related impurities coming from exposure to acid, base, or oxidizing agents. These studies help guarantee that during storage or compounding, terbutaline sulfate stays robust, giving every dose the same punch.
Terbutaline’s systematic chemical name, (±)-α-[(tert-butylamino)methyl]-3,5-dihydroxybenzyl alcohol sulfate, seldom shows up in pharmacy conversations. Instead, brand names like Bricanyl, Brethine, and Bronclyn lead in many countries. In scientific literature, references may list terbutaline hemisulfate, methylhydroxyphenylethanolamine, or simply “beta-2-mimetic”—but patients and doctors know to look for “terbutaline” or local market brandings. Keeping track of synonyms avoids confusion, especially with international suppliers and during cross-border regulatory filings, where a language barrier or similar-looking bottle can spell trouble.
Safe dispensing and administration of terbutaline rely on clear-cut protocols. Pharmacy storage demands keep products dry and shielded from direct sun. Nursing staff use strict double-checks for dosages and infusion rates in labor and delivery, since over-exposure can trigger tachycardia, hypokalemia, and pulmonary edema. The need for training runs deep: staff education covers adverse event recognition, IV line monitoring, and emergency setup in high-risk wards. Manufacturers must not only meet current Good Manufacturing Practices (cGMP) for every lot but also supply clear visual batch records and recall plans. Hospitals tie regular audits to risk management plans—eyeing everything from cold-chain logistics to the clarity of printed expiration dates. The lessons learned from near-misses with look-alike vials or incorrect dosing drive continuous improvement, keeping patient trust strong.
Doctors reach for terbutaline most often in managing asthma and chronic obstructive pulmonary disease—offering relief during acute attacks or as part of a maintenance protocol for moderate-to-severe cases. Emergency departments stock injectable forms for severe bronchospasm unresponsive to inhaled agents. In obstetrics, short-term terbutaline infusions can delay preterm labor and buy time for corticosteroids to mature fetal lungs, though changing guidelines have put firm limits on scope, duration, and patient selection due to emerging safety data. Coaches and anti-doping authorities also keep a close eye, as performance enhancement worries have landed terbutaline on most banned lists unless documented for medical exemption. Off-label investigations touch on hyperkalemia, bradycardia, and even experimental neuromuscular applications, but mainstream practice focuses squarely on the respiratory and obstetric spheres.
Research groups over the decades have dug deep into terbutaline’s molecular pharmacology. Early receptor mapping clarified the drug’s selectivity, paving the way for newer analogs. Clinical trials keep fine-tuning dosing schedules, age-based adjustments, and inhaler design improvements. Formulation scientists chase finer particle suspensions for deeper lung penetration, while novel delivery systems like dry-powder inhalers and autoinjectors move into trials. On the preclinical side, investigators deploy terbutaline as a model for beta-2 agonist action, unraveling the exact signal cascades and desensitization pathways that underlie tolerance or rebound bronchospasm. Animal models explore alternative routes—patches, sublingual films, and even implantable pumps—each pilot aimed at improving patient adherence and reducing side effects.
Toxicologists chart terbutaline’s risk profile by reviewing adverse event reports and dosing trials in both animals and humans. Typical symptoms of overdose include tremors, nervousness, insomnia, palpitations, and headaches—most due to over-stimulation of beta receptors. Cardiac arrhythmias and metabolic shifts, like hypokalemia and hyperglycemia, demand extra attention in vulnerable groups, such as those with heart disease or diabetes. Chronic exposure studies in animals have not flagged carcinogenicity, but reproductive risk draws strong caution, especially after the FDA reclassified prolonged obstetric use because of rare but severe maternal and fetal events. Side effect reporting and post-marketing surveillance continue globally, with pharmacovigilance teams updating labels and regulator guidance. Pharmacies respond to adverse event bulletins by refining patient screening and consistent patient education.
Looking ahead, terbutaline’s medical role will keep evolving alongside advances in respiratory care and pharmacogenetics. New beta-2 agonist molecules entering the pipeline must clear higher bars for both efficacy and cardiac safety, possibly chipping away at terbutaline’s share in some markets. On the formulation front, longer-acting devices and patches could offer more stability for patients with chronic needs. Biotechnologists scan terbutaline’s molecular traits for clues, searching for drug combinations or delivery boosters, such as nanoparticle carriers or gene therapy connectors, that might sharpen the therapeutic window even further. As the global asthma burden continues to rise and personalized medicine takes firmer root, terbutaline sulfate might see rebranding as part of fixed-dose triple therapies or as an agent in “smart” inhalers feeding data to clinicians. All of these shifts demand constant vigilance to quality, patient safety, and regulatory compliance, just as the field saw during those first decades after discovery.
Nobody appreciates a deep breath until it’s taken away. I remember as a teenager playing soccer, watching a teammate struggle for air during an asthma attack. He clutched his chest, and his entire body tensed up. The coach rushed over and pulled an inhaler from the first-aid kit. That was the first time I heard the name Terbutaline Sulfate.
Terbutaline Sulfate belongs to a group of medications known as bronchodilators. These drugs open up airways in the lungs. Doctors prescribe Terbutaline for people with asthma, chronic bronchitis, and emphysema—conditions where airways get tight or blocked. Those flare-ups feel like breathing with a cloth over the mouth, every gasp falling short. Terbutaline starts working within minutes, relaxing muscles and letting air through. That kind of relief can turn panic into a calm sigh.
During an asthma attack, seconds count. The body’s fight for oxygen ramps up stress hormones, making breathing tougher. Terbutaline Sulfate stands out since it acts quickly—faster than many long-term asthma medications that need hours to take effect. For folks like my old soccer teammate, this speed means fewer visits to the emergency room.
The medicine isn’t only for emergencies. Some doctors recommend small daily doses for people with ongoing breathing problems. It gives them a cushion. These folks can go grocery shopping or take a walk without worrying about their lungs closing up on them. Chronic lung diseases are isolating enough. Reliable relief, even temporary, opens doors to simple joys.
Terbutaline’s main job is in the lungs, but sometimes doctors use it for other reasons. Some try using it to delay early labor in pregnant women. The theory: if the drug relaxes airway muscles, maybe it will calm the womb too. The FDA has warned about safety risks when using Terbutaline for long stretches in pregnancy. Most experts ask women to avoid this use unless there’s no other choice, and not for more than a couple of days.
No drug works for everyone, and Terbutaline isn’t a magic bullet. People sometimes feel shaky, jittery, or their heart races—a sensation like a double shot of strong coffee. Long-term or high-dose use piles up risks, raising blood pressure and throwing off potassium levels. Some folks with heart rhythm problems, or those taking medications that mess with the heart, should stay away. I’ve met people who switched to other medications because the side effects felt worse than the wheezing.
It’s also easy to forget that overuse can dull the drug’s impact. The body can grow tolerant. If you find a rescue inhaler running out more than every couple of months, it’s time to talk with a doctor. I’ve seen people depend on Terbutaline like a security blanket, instead of asking for help to adjust their treatment.
Terbutaline Sulfate gives breathing room to those in a squeeze, but medicines only solve part of the problem. For asthma and lung disease, the biggest wins happen through quitting smoking, limiting exposure to pollution or workplace hazards, and sticking to an overall treatment plan. Doctors and respiratory therapists are key players. It helps to check in with them regularly, updating medications as health changes.
Getting to know the medications—how and when to use them, what symptoms signal trouble—can turn someone from a panicked patient into an empowered partner in their care. Terbutaline Sulfate stands as one helpful tool, not a cure-all. With the right knowledge and support, it’s possible to keep airways open and daily life moving forward.
Doctors prescribe terbutaline sulfate to help people who struggle to breathe easily. It relaxes muscles in the airways, mostly used for asthma, bronchitis, and emphysema. Many rely on this medication to get through the day. What doesn’t always come up in the examination room are the side effects that tag along once you leave the pharmacy.
Shakiness gets mentioned by nearly everyone who starts terbutaline. As a patient, feeling your fingers tremble after a dose feels startling at first, especially if you have to do tasks that demand steady hands. During a stretch where I cared for a family member who needed this medicine, we noticed the shakes most after the first few days, then a bit less as weeks went on.
Elevated heart rate shows up as well. Your heart picks up speed, sometimes beating so hard you can feel it thumping in your chest. Statistics say that palpitations and rapid pulse happen in roughly one out of three adults taking terbutaline, so it isn’t rare. This fast heartbeat can make it tough to relax or get decent sleep, turning simple nights into long ones.
A lot of folks notice headaches. Some describe it as a dull ache behind the eyes or a heaviness across the forehead. These headaches can mix with feeling nervous or restless. In conversations with others navigating asthma care, almost everyone had stories of struggling to focus or falling asleep while on this drug.
Dry mouth and nausea step into daily life for plenty. Drinking more water helped my family member, but even so, she often shared that her mouth felt like cotton. Upset stomach comes and goes with use, more common after an extra dose. For people who deal with nausea in other areas of life, this side effect can push them to skip doses—an issue far more common than many realize.
Sweating and muscle cramps aren’t talked about as much but still count among the usual complaints. Anyone who’s tried to sit through a hot day while sweating without a clear reason knows how embarrassing and uncomfortable it can be. Leg cramps sometimes show up early on, especially after activity, making walks feel unpredictable.
Mood changes catch people off guard. Some describe feeling extra anxious, or irritable, during the first weeks. People who already wrestle with anxiety often experience stronger feelings. Kids can get especially jumpy, and their parents often end up on edge as well, wondering if the medicine’s really helping enough to justify the new challenges at home.
Doctors and pharmacists can give practical advice to handle these side effects. For the shakes, splitting the dose or taking it earlier in the day can reduce disruptions. Staying well-hydrated cuts down on dry mouth. Tracking your pulse and paying attention to new symptoms keeps you alert for any bigger problems. For some, talking through options with a healthcare provider opens up alternatives—sometimes another medication with fewer risks, or a different delivery method that’s gentler on the body. Honest conversations and regular check-ins are the strongest tools, and as patient stories show, they make a big difference in getting the benefits without feeling overwhelmed by the drawbacks.
Breathing isn’t one of those things most of us think twice about—until it turns into a struggle. Rescue inhalers and bronchodilators become lifesavers at that point, and Terbutaline Sulfate is one of these trusted medicines. Commonly prescribed for asthma, bronchitis, and emphysema, its main job is to help open up the airways fast. People have been relying on it for years to relieve tight chests, wheezing, and cough that just won’t quit.
Terbutaline Sulfate comes as both a tablet and an injectable. Some days, tablets offer the easiest solution for people managing long-term symptoms. For sudden breathing attacks, doctors often grab the injection form because it acts quicker.
Pills get swallowed whole, usually with water. Most doctors set a reasonable schedule—often every six to eight hours. Chasing after relief by taking more than prescribed can backfire. Doses that land too close together or that creep past the recommended total don’t just miss the mark—they might cause rapid heartbeat, nervousness, or headaches. Taking the injection means relying on trained professionals at a clinic or hospital. I’ve seen nurses check and double-check dosing, especially for people battling other health issues or those on a pharmacy’s worth of medication.
Real life doesn’t always match perfectly with the neat chart taped on the medicine cabinet. I’ve watched friends fumble their schedules or forget if the last pill happened at breakfast or lunch. For folks juggling jobs, families, and all the regular curveballs of daily life, missing or doubling up on a dose feels all too easy. Technology now steps in: smartphone reminders, pill organizers, and support from family help keep the routine on track.
The injection side of this story hits differently. I’ve seen emergency departments whirl with urgency. Timing counts for everything. Prompt treatment can transform a frightening asthma attack into calm within minutes. That experience—watching someone literally breathe easier, right in front of you—drives home why precise, prompt dosing can’t be seen as optional.
Patients deserve to understand what goes into their bodies. Instructions from doctors and pharmacists work better with plain language and simple explanations. I remember leaving the pharmacy with my child’s new inhaler, full of questions—until a kind technician drew diagrams on the back of a napkin. Honest, clear conversations shut down confusion and prevent mistakes.
Careful communication gives people strength. Learning possible side effects, admission criteria, and emergency warning signs prepares everyone for what’s ahead. Too many times in my circle of friends, someone didn’t speak up about jitteriness or a racing pulse, thinking it was just part of asthma instead of a reaction to their medicine.
There’s always room for smarter processes. Doctors could spend more time at the outset, walking patients through pill schedules and showing the proper injection technique. Pharmacies can print clearer, step-by-step labels. Insurance companies can help make reminders and educational tools standard-issue for high-risk drugs like Terbutaline Sulfate.
All these steps add up. Each support builds confidence and safety, and makes relief much more likely. People living with asthma and similar conditions shouldn’t be left to guesswork. With enough teamwork from families and healthcare professionals, more folks breathe freely, and fewer wind up in emergency rooms across town.
Obstetricians see all sorts of medications offered as possible ways to prevent premature labor. Terbutaline sulfate, known for helping people with asthma breathe easier by relaxing muscles in the airways, sometimes gets mentioned in obstetrics. The thought behind its use in pregnancy: if it eases smooth muscle spasms in the lungs, maybe it can do the same for the uterus and keep contractions at bay. Women who hear their pregnancies might end too early often wonder if something as simple as an inhaler could be a solution. Doctors, stuck between hope and caution, want options—especially when families are desperate for anything that could buy a few more days or weeks for a baby to develop.
I’ve seen pregnant women prescribed terbutaline in the hospital or in a pinch for suspected preterm labor. It shows up in labor and delivery wards, sometimes by injection, sometimes as a pill. There’s no denying that it can stop contractions for the short term. But data from clinical trials and reports show the benefits don’t always last, and the risks start stacking up pretty quickly.
The U.S. Food and Drug Administration has been clear about this: terbutaline shouldn’t be used for extended times—more than a few days—in pregnant women because of potential heart problems for both mom and baby. Stories from mothers who’ve received high doses involve racing heartbeats, nervous jitters, and chest pain. In rare cases, serious heart complications have popped up in both infants and pregnant women. These real-world accounts echo the warnings in black-and-white FDA text. That’s why medical teams have largely shifted away from keeping women on terbutaline for weeks or sending them home with prescriptions.
I’ve heard some older doctors recount years where terbutaline pumps were standard fare for expectant mothers. Protocols have shifted after a mix of patient experiences, adverse event reports, and new studies. Younger obstetricians and maternal-fetal medicine specialists lean on other medications like nifedipine or magnesium sulfate, if they use tocolytics at all. Both pregnant women and doctors now ask deeper questions before trying these old-fashioned drugs. Scarce evidence points to terbutaline making a big enough long-term difference in preterm labor outcomes to outweigh possible harm. Most guidelines recommend a short window—maybe 48 hours—to give steroids time to mature a baby’s lungs, and then the terbutaline gets stopped.
Premature birth brings lifelong impacts, and the pressure to act hangs heavy in delivery rooms. Terbutaline’s story shows how medicine grapples with urgent problems in real time, sometimes with tools built for other jobs. Researchers and clinicians keep pushing for better therapies, improved prenatal care, and deeper education for women at risk. Many hospitals now use careful protocols that check a woman’s heart rate, blood pressure, and blood sugar before and after terbutaline, avoiding blanket use. Social support, regular prenatal visits, smoking cessation, and careful monitoring of high-risk pregnancies remain some of the real keys to lowering preterm birth rates.
Pregnancy can leave families staring down tough choices without easy answers. I’ve watched women and doctors walk through the data and listen to each other’s concerns before reaching for terbutaline or any other medication. Trust in the care team, transparent discussion of benefits and risks, and holding space for families’ questions seems to matter just as much as a prescription pad. Building real understanding and support for women at risk of preterm delivery pays off more than any single pill or injection—something fancy technology or new drugs alone can’t replace.
Prescriptions can get tangled, especially as folks age or pick up extra health problems. Terbutaline sulfate, a bronchodilator, lands in a lot of inhalers and pills for asthma. It kicks open tight airways so breathing eases up. Still, it doesn’t play nice with everything.
I talked to a pharmacist once after my uncle’s hospital trip. He had added a new blood pressure pill. Both medicines sped up his heart, giving him a shaking feeling that knocked him off balance for days. His doctor had to switch things up to avoid that clash.
Beta-blockers stand out as the top troublemakers with terbutaline. The drug revs the heart and opens lungs, but beta-blockers anchor the pulse and can tighten airways—exactly opposite moves. Mix the two and both drugs lose their punch, or worse, send the body into risky heart rhythms.
Diuretics sometimes join the conflict. These water pills lower potassium, a mineral that muscles, including the heart, need to work right. Terbutaline can also drop potassium. That tag-team dip makes muscle cramps and arrhythmias more likely.
Certain antidepressants, especially tricyclics or MAO inhibitors, take things up a notch. They can multiply the jittery, rapid heartbeat and blood pressure spikes that terbutaline sometimes triggers on its own. Then there’s the risk of some antibiotics like erythromycin, which push the heart’s rhythm into dangerous danger zones if paired with terbutaline.
Anyone with heart trouble faces extra risk from terbutaline. Parents with kids who already go to the cardiologist probably got that warning from their doctor, but it sometimes gets missed in busy clinics. Terbutaline’s job is to excite certain receptors—helpful in the lungs, not so much for an already stressed heart. Someone with arrhythmia, high blood pressure, or even a thyroid that’s always stuck in overdrive can end up in the hospital from one wrong inhaler.
Diabetes brings another layer of worry. Terbutaline spikes blood sugar. I’ve seen friends’ blood glucose numbers rocket after a single dose, followed by a fast drop. Crisis-level highs and lows come fast if someone’s not keeping an eye on their insulin routine and diet.
Glaucoma patients must tread carefully, too. Terbutaline sparks pressure in the eyes, which risks long-term damage if left unchecked.
Nobody can memorize every possible drug interaction. People can ask questions before filling a prescription. Bringing a note listing every pill—over-the-counter stuff counts—into the clinic during check-ups can spare a lot of grief. Pharmacists are trained to catch red flags, but only if they know everything someone’s taking.
Smartphone apps (like Medisafe or MyTherapy) help track all meds and flag bad combinations. Setting up electronic health records with up-to-date allergies and drug lists can prevent errors, even during emergencies when communication slips.
People with heart conditions, diabetes, glaucoma, or anyone juggling more than three prescriptions should check in with their doctor or pharmacist about terbutaline. Honest talks, double-checking labels, and never stopping or starting a new medicine without a game plan save lives. If something feels off—palpitations, tremors, blurred vision—it’s better to call for help early, not just wait and hope things pass.
Science moves fast. Drug guides change every year or two as new findings hit the journals. Sticking to open conversations and taking careful notes at appointments can handle most interactions before they spiral into big problems.
| Names | |
| Preferred IUPAC name | 4-[2-(tert-Butylamino)-1-hydroxyethyl]benzene-1,2-diol sulfate |
| Other names |
Airomir Bricanyl Brethine |
| Pronunciation | /ter-ˈbyuː-tə-liːn ˈsʌl.feɪt/ |
| Identifiers | |
| CAS Number | 23031-25-6 |
| Beilstein Reference | 3612970 |
| ChEBI | CHEBI:9458 |
| ChEMBL | CHEMBL1437 |
| ChemSpider | 15916 |
| DrugBank | DB00871 |
| ECHA InfoCard | echa.europa.eu/substance-information/-/substanceinfo/100.036.035 |
| EC Number | EC 200-945-5 |
| Gmelin Reference | 1314886 |
| KEGG | D01405 |
| MeSH | D013736 |
| PubChem CID | 60747 |
| RTECS number | XN8575000 |
| UNII | 1TR29JZK6Z |
| UN number | Not regulated |
| Properties | |
| Chemical formula | C12H19NO3·H2SO4 |
| Molar mass | 548.65 g/mol |
| Appearance | White or off-white crystalline powder |
| Odor | Odorless |
| Density | 0.5 g/cm3 |
| Solubility in water | Soluble in water |
| log P | -1.3 |
| Vapor pressure | Negligible |
| Acidity (pKa) | 9.56 |
| Basicity (pKb) | 4.4 |
| Magnetic susceptibility (χ) | -65.0×10⁻⁶ cm³/mol |
| Dipole moment | 3.53 D |
| Thermochemistry | |
| Std molar entropy (S⦵298) | 289 J·mol⁻¹·K⁻¹ |
| Pharmacology | |
| ATC code | R03AC03 |
| Hazards | |
| Main hazards | Harmful if swallowed. May cause respiratory and cardiovascular effects. May cause allergic skin reactions. Dust may cause irritation to respiratory tract, eyes, and skin. |
| GHS labelling | GHS05, GHS07 |
| Pictograms | GHS07 |
| Signal word | Warning |
| Hazard statements | H302: Harmful if swallowed. H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation. |
| Precautionary statements | Keep out of reach of children. In case of accidental overdose, seek professional assistance or contact a poison control center immediately. |
| NFPA 704 (fire diamond) | 1-2-0 |
| Flash point | > 293.1°C |
| Autoignition temperature | 410°C |
| Lethal dose or concentration | LD₅₀ (rat, oral): 1650 mg/kg |
| LD50 (median dose) | LD50 (median dose): Mouse (oral): 1650 mg/kg |
| NIOSH | TN8400000 |
| PEL (Permissible) | Not established |
| REL (Recommended) | 2.5–5 mg every 4–6 hours |
| IDLH (Immediate danger) | Unknown |
| Related compounds | |
| Related compounds |
Epinephrine Albuterol Metaproterenol Salbutamol Fenoterol Orciprenaline Isoprenaline Tulobuterol |
