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Material Safety Data Sheet: Sulfato de Brucina Heptahidratado

Identification

Product Name: Sulfato de Brucina Heptahidratado
Chemical Formula: C46H52N4O12S•7H2O
CAS Number: 5892-11-7
Synonyms: Brucine Sulfate Heptahydrate
Recommended Use: Laboratory reagent, chemical analysis, and research applications.
Manufacturer Information: Refer to supplier data, typically located on packaging or sales documentation.
Emergency Contact: National Poison Center, local emergency services, and supplier emergency line.

Hazard Identification

Classification: Toxic if swallowed or inhaled, skin and eye irritant, hazardous to aquatic environments.
Signal Word: Danger
Hazard Statements: Causes serious health risks upon exposure; may damage organs; toxic to aquatic life with long-lasting effects.
Precautionary Statements: Avoid all contact with skin, eyes, and clothing. Do not eat, drink, or smoke while using. Keep away from drains, soil, and all waterways.
GHS Label Elements: Skull and crossbones, exclamation mark, environmental hazard pictogram.
Routes of Exposure: Inhalation, ingestion, skin and eye contact.

Composition / Information on Ingredients

Chemical Name: Sulfato de Brucina Heptahidratado
CAS Number: 5892-11-7
Concentration: 100% (pure substance)
Impurities: Laboratory grade materials should have minimal impurities, although contamination from handling may occur.

First Aid Measures

Inhalation: Move the person to fresh air. Keep them at rest. If breathing stops, provide artificial respiration and contact medical personnel immediately.
Skin Contact: Remove contaminated clothing. Wash skin thoroughly with soap and water for at least 15 minutes. Use emergency shower if present.
Eye Contact: Rinse with plenty of water for several minutes, lifting upper and lower eyelids occasionally. Remove contact lenses if present. Seek medical attention.
Ingestion: Do not induce vomiting. Rinse mouth with water thoroughly. Get immediate medical assistance.
Medical Attention: Provide the chemical name and SDS to healthcare providers. Symptoms may include confusion, muscular convulsions, respiratory depression, and cardiovascular effects.

Fire-Fighting Measures

Suitable Extinguishing Media: Use carbon dioxide, dry chemical powder, or alcohol-resistant foam. Water may be ineffective for extinguishing but can cool containers.
Specific Hazards Arising from Chemical: Fire may produce toxic fumes including nitrogen oxides, sulfur oxides, and carbon monoxide.
Protective Equipment: Firefighters should use self-contained breathing apparatus and full protective gear.
Advice: Move containers from the fire area if this can be done without risk. Evacuate personnel to a safe zone.

Accidental Release Measures

Personal Precautions: Wear chemical-resistant gloves, safety goggles, lab coat, and respiratory protection. Do not touch or walk through spilled material.
Environmental Precautions: Prevent entry into sewers, soil, and waterways. Notify authorities if large amounts escape.
Containment and Cleaning: Use inert absorbent material (sand, vermiculite). Scoop up residue and put in appropriate chemical waste container. Clean spill area after removal using detergent and copious water.

Handling and Storage

Handling: Only use inside well-ventilated chemical fume hood. Avoid conditions leading to dust or aerosol formation. Keep away from food and drinks.
Storage Conditions: Store in tightly closed, labeled container inside cool, dry, and dark chemical storage cabinet, away from incompatible materials such as strong oxidizers.
Storage Temperature: Maintain at ambient temperature, away from direct sources of heat, flame, and sunlight.
Incompatible Materials: Strong acids, strong bases, and strong oxidizing agents.

Exposure Controls and Personal Protection

Exposure Limits: No established occupational exposure limits; treat as highly toxic.
Engineering Controls: Use local exhaust, chemical fume hood, or laboratory glove box.
Personal Protective Equipment: Chemical-resistant gloves (nitrile recommended), splash-proof safety goggles, laboratory coat, and appropriate respiratory protection when dust or aerosols are present.
Hygiene: Wash hands and face thoroughly after handling. Remove contaminated clothing and launder before reuse.

Physical and Chemical Properties

Appearance: White to off-white crystalline powder
Odor: Odorless
pH (aqueous solution): Not available
Melting Point/Freezing Point: Decomposes before melting
Solubility: Soluble in water
Boiling Point: Not applicable
Flash Point: Not flammable
Density: Data not widely available
Vapor Pressure: Not applicable
Other Information: Molecular weight 977.1

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions.
Possibility of Hazardous Reactions: May react violently with strong oxidizing or reducing agents.
Hazardous Decomposition Products: Toxic and irritating gases such as nitrogen oxides, sulfur oxides, and carbon oxides may form during combustion.
Conditions to Avoid: Avoid dust generation, exposure to heat, open flame, and incompatible substances.

Toxicological Information

Acute Toxicity: Brucine derivatives have low LD50 values, indicating high toxicity via oral, dermal, and inhalation routes.
Chronic Effects: Nervous system damage, liver and kidney impairment, increased risk of convulsions and death after repeated exposures.
Symptoms of Exposure: Nausea, dizziness, confusion, muscular twitching, convulsions, respiratory failure.
Carcinogenicity: No current evidence suggests carcinogenic potential; further research necessary.
Mutagenicity/Teratogenicity: Data insufficient for conclusions, but brucine compounds may pose reproductive risks.

Ecological Information

Ecotoxicity: Highly toxic to aquatic life. Even small quantities may cause long-term adverse effects in the aquatic environment.
Mobility in Soil: High water solubility suggests potential for leaching into groundwater.
Persistence and Degradability: Data lacking; persistence expected.
Bioaccumulation Potential: Unknown; measurable accumulation likely based on structural similarity to other alkaloids.
Other Adverse Effects: Release to the environment must be avoided.

Disposal Considerations

Waste Treatment Methods: Incinerate in a chemical incinerator equipped with afterburner and scrubber.
Disposal of Product: Dispose as hazardous laboratory chemical waste according to federal, state, and local regulations. Do not discharge to sewer systems.
Contaminated Packaging: Triple rinse before disposal; treat residues as hazardous.
Precautions: Wear protective gear during disposal; label all containers properly.

Transport Information

UN Number: UN 2811
Proper Shipping Name: Toxic solid, organic, n.o.s. (Sulfato de Brucina Heptahidratado)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: II
Environmental Hazards: Marine pollutant, avoid aquatic release
Special Precautions: Keep tightly sealed and upright. Transport according to regulations for toxic substance handling.

Regulatory Information

Chemical Inventory Status: May not appear on all international inventories—verify for each jurisdiction
Labeling Requirements: Follow Globally Harmonized System and local chemical labeling regulations
Workplace Controls: Subject to chemical hygiene plans, laboratory safety standards, and high-risk material handling protocols.
Restrictions: Strictly for laboratory, research, or analytical use. Not for food, drug, or household use.
Other National or Local Requirements: Confirm compliance with OSHA, EPA, European REACH, and local government bodies.