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Product Name: Sodium Citrate Dihydrate
Chemical Formula: C6H5Na3O7·2H2O
Synonyms: Trisodium citrate dihydrate, Citric acid trisodium salt dihydrate
CAS Number: 6132-04-3
Recommended Use: Commonly used as a buffering agent, emulsifier, and preservative in food, beverages, and pharmaceuticals. Found in laboratories and industrial applications for water softening and providing anticoagulant properties in blood storage.
Supplier: Manufacturer or distributor details supplied on shipment or invoice documentation; emergency contact information typically updated yearly.
Contact Numbers: For local emergencies, call national poison control or fire department, or consult the provided supplier 24-hour emergency hotline on product packaging.
Classification: Sodium Citrate Dihydrate does not meet the criteria for hazardous classification according to OSHA Hazard Communication Standard.
Signal Word: Not applicable.
Hazard Statements: May cause mild eye irritation and slight discomfort if inhaled as dust. Not widely recognized as hazardous; ingestion of large quantities can lead to metabolic imbalances or gastrointestinal upset.
Precautionary Statements: Avoid creating and breathing dusts. Wash hands thoroughly after handling. Use with adequate ventilation. Call a doctor if feeling unwell after exposure.
Hazard Pictograms: Not required.
Other Hazards: Spilled powder may cause slips and falls. No acute toxicity, but always treat unknown reactions promptly.
Chemical Name: Sodium Citrate Dihydrate
Common Name: Citric Acid Trisodium Salt Dihydrate
CAS Number: 6132-04-3
Concentration: >99% by weight
Impurities: Contains trace amounts of water and unbound citrate, less than 1%. Not known to include hazardous impurities under common manufacturing practices.
Inhalation: Remove to fresh air if dust is inhaled in excessive amounts. Seek medical attention if coughing or discomfort persists. Avoid panic, and support breathing with oxygen if needed.
Skin Contact: Remove contaminated clothing. Flush skin with water for several minutes. Seek medical assistance for persistent irritation.
Eye Contact: Rinse carefully under running water for several minutes, keeping eyelids open. Seek medical help if a burning or gritty sensation continues.
Ingestion: Rinse mouth thoroughly with water. Drink water to dilute. Do not induce vomiting unless directed by medical personnel. Consult a toxicology professional if large quantities are swallowed.
Important Symptoms: Mild skin, eye, or respiratory tract irritation. Ingestion may lead to minor gastrointestinal upset in sensitive individuals.
Note to Physician: Treat symptomatically with supportive measures. High doses may cause metabolic alkalosis or mild electrolyte disturbances.
Suitable Extinguishing Media: Water spray, dry chemical powder, carbon dioxide, or foam.
Unsuitable Extinguishing Media: Avoid high-pressure water streams that may scatter dry powder.
Specific Hazards: Sodium Citrate Dihydrate is non-flammable and does not support combustion. Under intense heat, decomposition can generate carbon oxides and irritating fumes.
Special Protective Equipment: Firefighters should wear self-contained breathing apparatus and protective clothing to prevent contact with decomposition products.
Fire-Fighting Instructions: Cool unaffected containers with water. Prevent runoff from contaminating groundwater or waterways. Remain upwind if fumes are present.
Personal Precautions: Use appropriate respiratory and eye protection if airborne dust is present. Clear the area of unnecessary personnel.
Environmental Precautions: Prevent release into drains, sewers, or aquatic environments at substantial levels. Small amounts in typical cleaning solutions present low risk.
Methods for Clean-Up: Sweep up spilled material with tools that do not create excessive dust. Transfer to labeled containers for disposal. Use damp cloths for final cleaning to minimize dust residue.
Reference to Other Sections: Consult exposure control and disposal guidance for additional instructions.
Handling: Keep containers tightly closed when not in use. Minimize dust generation by opening containers slowly and using local exhaust ventilation. Wash thoroughly after handling and before eating, drinking, or smoking.
Storage: Store in a cool, dry, well-ventilated area, protected from moisture. Avoid contact with acids and incompatible materials. Keep product in original or properly labeled containers.
Incompatible Materials: Strong acids, strong oxidizers. Do not store near food or beverages for human consumption.
Handling Practices: Use straightforward manual handling, but wear gloves and safety goggles if exposure is likely.
Exposure Limits: No specific exposure limits established by OSHA, ACGIH, or NIOSH.
Engineering Controls: Provide adequate general and/or local exhaust ventilation. Eye wash stations and emergency showers recommended in areas of bulk handling.
Personal Protection: Wear safety glasses or goggles to protect against dust. Use dust masks or particulate respirators for heavy exposure. Standard laboratory gloves protect against minimal contact. Wash hands and face after handling, and launder clothing regularly.
Additional Precautions: Remove contaminated clothing straightaway. Routine change of work clothing recommended to stop track-out.
Appearance: White, crystalline granules or powder.
Odor: Odorless.
pH: 7.5 to 9.0 (5% aqueous solution)
Melting Point: Decomposes above 150 °C
Boiling Point: Not applicable (decomposes before boiling)
Solubility (Water): Highly soluble
Density: 1.7–1.9 g/cm³ (bulk)
Vapor Pressure: Negligible at room temperature
Flash Point: Not flammable
Evaporation Rate: Not relevant (solid material)
Partition Coefficient (n-Octanol/Water): Not determined
Other Data: Hygroscopic; absorbs moisture from air if left open.
Chemical Stability: Stable under normal storage and handling conditions.
Reactivity: Reacts with strong acids to release citric acid and sodium salts.
Hazardous Reactions: None anticipated under recommended storage and handling.
Conditions to Avoid: High humidity, exposure to strong acids or sources of intense heat.
Incompatible Materials: Reactive with strong oxidizers, acids. May react with magnesium and other metals to produce hydrogen.
Hazardous Decomposition Products: At high temperatures, produces carbon oxides (CO, CO2), sodium oxides, and irritating fumes.
Acute Toxicity: Data shows oral LD50 in rats greater than 8,000 mg/kg body weight, indicating very low toxicity.
Skin Corrosion/Irritation: No significant irritation reported in standard animal and human exposure tests.
Eye Damage/Irritation: Dust may cause mild, reversible irritation.
Respiratory Irritation: Inhalation of dust may trigger temporary respiratory discomfort or coughing, particularly for those with pre-existing respiratory issues.
Chronic Effects: Prolonged or repeated exposure is not expected to pose health risks. No evidence links this compound to carcinogenic, mutagenic, or reproductive hazards.
Routes of Exposure: Inhalation, skin contact, ingestion, and eye contact.
Symptoms: Mild gastrointestinal upset, coughing, or eye irritation if in dusty environments or ingested in large amounts.
Other Toxicity Data: Metabolized in the body as citrate; excess possible only at doses much greater than any practical or occupational use.
Ecotoxicity: Experiments show low toxicity to aquatic organisms; LC50 (96h, fish) generally above 1,000 mg/L.
Persistence and Degradability: Readily biodegradable; breaks down in the environment to water and carbon dioxide.
Bioaccumulation: Not expected to bioaccumulate in aquatic or terrestrial systems.
Mobility: Highly soluble in water and can move through soil easily.
Other Environmental Information: Environmental releases should stay within permissible concentration limits to avoid overwhelming sewage or water treatment capacity.
Waste Treatment Methods: Small quantities can go to landfill or be flushed to wastewater treatment if local regulations allow.
Container Disposal: Clean and recycle or dispose of containers according to local requirements. Avoid reusing packaging for food or personal use.
Hazardous Waste Code: Product not classified as hazardous waste under U.S. RCRA regulations.
Precautions: Keep material dry and minimize airborne dusts during disposal. Check with environmental authorities for regional rules.
UN Number: Not regulated for ground, air, or sea transport.
UN Proper Shipping Name: Not applicable
Transport Hazard Class: Not applicable (non-hazardous material)
Packing Group: Not applicable
Special Transport Precautions: Avoid contact with moisture. Secure containers to prevent spillage or release during transit.
Regulations: Not listed as dangerous goods by IATA, IMDG, or DOT.
OSHA: Not considered hazardous under OSHA Hazard Communication Standard.
TSCA: Listed in the U.S. Toxic Substances Control Act (TSCA) Inventory.
SARA Title III: Not subject to reporting under Sections 302, 304, 313.
Right to Know: Not listed under California Proposition 65 or other regional chemical restrictions.
Other Regulatory Statuses: FDA approved as food additive E331 for multiple uses. Not subject to special U.S. or EU import/export controls.
Label Elements: No pictograms, signal words, or hazard statements required for standard workplace labeling.
