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Material Safety Data Sheet: 3,5-Dinitrosalicylic Acid

Identification

Product Name: 3,5-Dinitrosalicylic Acid
Synonyms: DNS, 2-Hydroxy-3,5-dinitrobenzoic acid
CAS Number: 609-99-4
Recommended Use: Laboratory reagents, chemical analysis (reducing sugars analysis)
Manufacturer: Chemical suppliers, laboratory reagent distributors
Emergency Contact: Local poison control, emergency medical services, or facility responsible for chemical safety

Hazard Identification

GHS Classification: Acute Toxicity (Oral, Dermal, Inhalation), Skin Irritant, Eye Irritant
Pictogram: Exclamation mark, health hazard
Signal Word: Warning
Hazard Statements: Harmful if inhaled, swallowed, or in contact with skin. May cause respiratory irritation, eye irritation, and skin irritation.
Precautionary Statements: Avoid breathing dust or vapors. Wash hands after handling. Wear protective gloves and eye/face protection.

Composition / Information on Ingredients

Chemical Name: 3,5-Dinitrosalicylic Acid
Molecular Formula: C7H4N2O7
Molecular Weight: 228.12 g/mol
Concentration: 98% or above in standard reagent form
Impurities: Trace organic or inorganic contaminants from synthesis may be present in technical grade materials

First Aid Measures

Inhalation: Move to fresh air. Seek medical attention if symptoms develop or persist. Avoid rescue without respiratory protection.
Skin Contact: Remove contaminated clothing, wash skin thoroughly with soap and water. If irritation persists, seek medical attention.
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses if possible. Seek immediate medical advice.
Ingestion: Rinse mouth. If the person is conscious, have them drink water. Do not induce vomiting without medical guidance. Seek medical help promptly.

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, CO2, foam, or water spray
Unsuitable Extinguishing Media: High pressure water streams
Hazardous Combustion Products: Nitrogen oxides, carbon oxides, potentially irritating or toxic fumes
Firefighter Protection: Use self-contained breathing apparatus and full protective gear
Special Hazards: Dust may form explosive mixtures with air. Material may intensify fire due to oxidizing potential.

Accidental Release Measures

Personal Precautions: Wear chemical resistant gloves, goggles, and a dust mask or respirator.
Environmental Precautions: Avoid release into drains, sewers, and water bodies.
Cleanup Methods: Sweep up carefully to avoid dust generation. Use damp cloths for final cleanup. Dispose of residues in accordance with local regulations.

Handling and Storage

Handling: Handle with local exhaust ventilation. Avoid breathing dust. Use tools and containers that do not generate sparks.
Storage: Store in a tightly sealed container in a cool, dry, well-ventilated area. Keep away from incompatible materials such as reducing agents, strong bases, and oxidizers.
Storage Temperature: Store below 30°C for long-term stability.
Other Instructions: Avoid direct sunlight and sources of ignition. Label container clearly.

Exposure Controls and Personal Protection

Exposure Limits: No specific occupational exposure limits set by OSHA, NIOSH, or ACGIH.
Engineering Controls: Fume hood or local exhaust ventilation.
Personal Protective Equipment: Chemical resistant gloves, lab coat, safety goggles, and appropriate respiratory protection for dust.
Hygiene Practices: Wash hands and face after handling, before eating, drinking, or smoking. Remove contaminated clothing.

Physical and Chemical Properties

Appearance: Yellow to orange crystalline powder
Odor: Slight, characteristic
Melting Point: 174-176°C
Boiling Point: Decomposes before boiling
Solubility: Soluble in water, ethanol, and methanol
pH: Slightly acidic in aqueous solution
Vapor pressure: Negligible at room temperature
Relative Density: 1.7–1.8 g/cm³
Partition Coefficient (n-octanol/water): Data not easily obtainable—low likelihood of bioaccumulation
Flash Point: Not applicable in solid form
Explosive Properties: Dust explosion risk under certain conditions

Stability and Reactivity

Chemical Stability: Stable under recommended storage and handling.
Reactivity: May react with strong bases, reducing agents, and combustibles.
Hazardous Decomposition: Nitrogen oxides, carbon oxides on decomposition.
Conditions to Avoid: Heat, sparks, open flames, moisture.
Incompatible Materials: Strong acids, reducing agents, active metals, strong oxidizers.

Toxicological Information

Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Harmful by inhalation and ingestion. May cause nausea, vomiting, dizziness, and respiratory irritation.
Chronic Toxicity: Prolonged or repeated exposure may cause dermatitis or persistent respiratory irritation.
Skin Sensitization: Not well documented
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, or OSHA
Mutagenicity / Teratogenicity: Data not conclusive, avoid unnecessary exposure

Ecological Information

Ecotoxicity: Harmful to aquatic organisms; high concentrations threaten water quality and aquatic life.
Persistence and Degradability: Moderately persistent in the environment.
Bioaccumulation Potential: Low, based on physical properties.
Mobility in Soil: Moderate, can leach through soil with water.
Other Comments: Prevent release to the environment whenever possible.

Disposal Considerations

Waste Disposal Methods: Collect and dispose of waste and contaminated packaging in accordance with federal, state, and local environmental regulations.
Contaminated Packaging: Triple rinse containers before disposal, or use professional chemical waste services.
Disposal Precautions: Do not pour down drains or waterways. Incineration at approved facilities may be suitable.

Transport Information

UN Number: 1325
UN Proper Shipping Name: Flammable solid, organic (contains 3,5-Dinitrosalicylic acid)
Transport Hazard Class: 4.1 (Flammable solid)
Packing Group: II
Environmental Hazards: Caution if released during transit
Special Precautions for Transport: Keep away from sources of ignition, handle with care to prevent container damage during transit.

Regulatory Information

OSHA Status: Hazardous chemical under OSHA Hazard Communication Standard
TSCA: Listed on the United States Toxic Substances Control Act (TSCA) inventory
REACH Compliance: Registered substance in the EU REACH database
SARA Title III: Not subject to specific reporting under Sections 302, 304, or 313
California Proposition 65: Not listed as a chemical known to cause cancer or reproductive toxicity
Other International Regulations: Listed or regulated in national inventories for Canada, EU, Australia, Japan, and other countries.