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Product Name: Pur-A-Lyzer Mega Dialysis Kit
Product Usage: Laboratory dialysis of proteins, peptides, and other biological samples
Manufacturer: Sigma-Aldrich, 3050 Spruce St., St. Louis, MO 63103, USA
Telephone Number: +1-800-325-3010
Emergency Telephone: CHEMTREC: 1-800-424-9300
Product Code: Refer to label on package
Email: safety@sigmaaldrich.com
GHS Classification: Not classified as hazardous under GHS
Main Hazards: May cause minor irritation to eyes and skin on prolonged contact, not intended for ingestion or inhalation
Signal Word: None
Hazard Statements: None specific, though repeated contact or improper disposal can pose a risk
Precautionary Statements: Handle using good laboratory practices, do not eat, drink, or smoke when using
Other Information: Components are sealed in a membrane, exposure only possible by damage or improper use
Dialysis Membrane Material: Cellulose ester or regenerated cellulose (~99%)
Preservative (if present): Trace sodium azide (CAS 26628-22-8) ≤0.01%
Buffer Retainers: Non-hazardous polymer beads or spacers
Moisturizing Agent: Water (CAS 7732-18-5) as packing moisture
Other Additives: None identified
Hazardous Impurities: Not expected above regulatory thresholds
Eye Contact: Rinse cautiously with water for several minutes, seek medical advice if irritation persists
Skin Contact: Remove contaminated clothing, wash with soap and water, medical attention if reaction occurs
Inhalation: Move person to fresh air if membrane dust or preservative fumes are inhaled accidentally
Ingestion: Rinse mouth, drink water, seek immediate medical attention
Notes to Physician: Symptomatic treatment only, no specific antidote
Contact Information: Use manufacturer’s emergency number for further guidance
Suitable Extinguishing Media: Water spray, foam, dry powder, carbon dioxide
Specific Hazards Arising: Burning membrane may emit carbon monoxide, carbon dioxide, formaldehyde
Special Protective Equipment: Firefighters use self-contained breathing apparatus
Firefighting Procedures: Remove product from fire area if safe, cool any intact containers with water
Combustion Products: Toxic fumes, avoid inhaling smoke
Explosion Risk: Not classified as explosive
Personal Precautions: Wear gloves, goggles, lab coat
Environmental Precautions: Prevent entry into drains, waterways, soil
Containment Methods: Collect material and dispose in appropriate waste container
Clean-Up Methods: Wash spill site with water after collection, ventilate area
Waste Disposal: See Disposal Considerations
Safe Handling Advice: Keep sealed until use, avoid damaging membranes, handle with dry gloves
Hygiene Measures: Wash hands thoroughly after use, do not eat or drink in work area
Safe Storage Conditions: Store in cool, dry place, away from direct sunlight and incompatible materials
Packaging Materials: Keep in original packaging, reseal unused devices
Incompatibilities: Strong acids and bases, oxidizing agents
Occupational Exposure Limits: No workplace exposure limits set for primary components
Engineering Controls: Use in well-ventilated area, laboratory fume hood preferred for open devices
Personal Protective Equipment: Chemical-resistant gloves, eye protection, lab coat
Respiratory Protection: Not required under normal conditions, dust mask if powder or degraded product handled
Hygiene Practices: No open food or drink, routine hand washing after use
Environmental Controls: Do not allow disposal into environment
Appearance: Tubular cartridge with clear or opaque membrane, sometimes in liquid solution
Odor: Odorless
Solubility: Membrane insoluble in water, may swell, preservative highly soluble
pH: Not applicable for device, preservative solution near neutral
Boiling Point: Not applicable, device not designed for heating
Melting Point: >100°C (membrane chars at high temperature)
Density: 1.2-1.5 g/cm3 for membrane material
Vapor Pressure: Not applicable
Flammability: Will burn at high temperatures
Other Data: No data indicating unusual physical or chemical reactivity under normal conditions
Chemical Stability: Stable under recommended storage and handling conditions
Thermal Decomposition: Degrades at high temperature, releases irritant fumes
Materials to Avoid: Concentrated oxidizers, strong acids/bases
Hazardous Polymerization: Will not occur
Conditions to Avoid: Direct flame, strong UV light, excessive moisture
Decomposition Products: Carbon oxides, formaldehyde, trace nitrogen oxides
Acute Toxicity: Low by all routes of exposure under normal laboratory conditions
Chronic Effects: No known chronic health effects with normal handling
Sensitization: Components do not contain known sensitizers
Irritation: Mild skin and eye irritation possible
Inhalation Exposure: No significant hazard under intended use, avoid inhaling particulate or dust
Carcinogenicity: Not listed as carcinogenic by IARC, NTP, OSHA
Additional Data: Occupational exposures monitored in compliant laboratories have not shown adverse effects
Eco-toxicity: Not expected to pose hazard to aquatic life at expected concentrations
Persistence and Degradability: Membrane biodegradable over time by environmental bacteria
Bioaccumulation: No significant bioaccumulation expected
Mobility: Device not mobile, contents insoluble and unlikely to migrate in soil
Other Adverse Effects: Sodium azide (preservative) toxic to aquatic organisms at high concentration; keep out of waterways
Product Disposal: Treat membrane and used kit as laboratory waste, follow all institutional and regulatory guidelines
Contaminated Packaging: Dispose of empty packaging in accordance with municipal or institutional regulations
Environmental Precautions: Do not dispose of material or wash solutions into public sewers or natural waterways
Recommended Method: Approved landfill or incinerate with appropriate permits
Special Considerations: If sodium azide is present, decontaminate with 10% sodium nitrite solution before drain disposal (follow local laws)
UN Number: Not classified as hazardous for transport
Transport Hazard Class: Not restricted
Packing Group: Not applicable
Proper Shipping Name: Not regulated
Environmental Hazards: Avoid spills in transit, use secondary containment when shipping liquids
Special Precautions: Protect from puncture or physical damage during transport
Regulation Compliance: Device complies with FDA, CE, and relevant ISO standards for laboratory equipment
Hazard Communication: Not classified under OSHA Hazard Communication Standard
RoHS/REACH Status: Components free from listed hazardous substances above legal thresholds
Global Chemical Inventories: All ingredients appear in TSCA, EINECS
Other Specific Regulations: Import, use, and disposal governed by local country regulations; sodium azide monitoring may be required based on content
Label Elements: Product labels include warning symbols, safe handling instructions, contact details for emergencies
