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Product Name: Propylene Glycol
Chemical Formula: C3H8O2
CAS Number: 57-55-6
Synonyms: 1,2-Propanediol, Propane-1,2-diol
Recommended Use: Solvent, Humectant, Food additive, Pharmaceutical ingredient, Cosmetic component
Supplier Details: Manufacturer name, address, and contact information listed on packaging or technical specifications
Emergency Contact: Emergency phone number specific to regional or international regulations
Hazard Classification: Not classified as hazardous according to GHS criteria
Signal Word: None required
Hazard Statements: May cause mild eye irritation, low hazard for usual industrial or commercial handling
Pictograms: No specific pictogram required by GHS
Precautionary Statements: Avoid eye and prolonged skin contact, avoid ingestion in large amounts, practice good industrial hygiene
Chemical Name: Propylene Glycol
Concentration: ≥99% by weight
Impurities: Water (trace), organic byproducts (trace, subject to supplier QA/QC), no known hazardous impurities in standard grades
Ingredients Information: Substance is considered pure for labeling purposes; consult manufacturer for details on trace components
Eye Contact: Rinse immediately with plenty of water for at least 10-15 minutes, remove contact lenses if present and easy to do, seek medical attention if irritation persists
Skin Contact: Wash thoroughly with soap and water, remove contaminated clothing and shoes, seek medical attention if irritation develops or persists
Inhalation: Move person to fresh air, provide oxygen if breathing is difficult, seek medical attention for prolonged exposure or respiratory symptoms
Ingestion: Rinse mouth with water, do not induce vomiting, give water to drink if the exposed person is conscious, seek medical advice for large ingestion or symptoms
Suitable Extinguishing Media: Water spray, dry chemical, foam, carbon dioxide
Unsuitable Extinguishing Media: High volume water jet, avoid using if risk of contamination or spillage increases
Specific Hazards: May emit toxic vapors under fire conditions: carbon monoxide, carbon dioxide
Protective Equipment: Firefighters should wear full protective gear and self-contained breathing apparatus
Other Instructions: Cool exposed containers with water spray to prevent rupture, control run-off to prevent environmental contamination
Personal Precautions: Isolate spill area, provide adequate ventilation, use PPE such as gloves and goggles
Environmental Precautions: Prevent entry to sewers and waterways, notify authorities if significant spillage contaminates environment
Clean-Up Methods: Soak up with inert absorbent material such as sand or earth, place in suitable containers for disposal, wash spill site after material pick-up is complete
Handling Precautions: Avoid inhaling vapor or mist, avoid contact with eyes and skin, use appropriate ventilation, wash hands after handling
Storage Conditions: Store in tightly closed, clearly labeled containers in a cool, dry, well-ventilated area
Special Requirements: Protect from moisture and direct sunlight, store away from strong oxidizing agents, acids, and bases
Incompatibilities: Strong oxidizers, strong acids, strong bases, materials leading to hazardous polymerization
Occupational Exposure Limits: ACGIH TLV: 10 mg/m³ (inhalable fraction, aerosol)
Engineering Controls: Install adequate ventilation and local exhaust, provide eyewash stations and safety showers
Personal Protective Equipment: Safety glasses with side-shields, chemical-resistant gloves (nitrile, neoprene), protective clothing to prevent skin exposure, use respiratory protection if ventilation is inadequate
Hygiene Measures: Wash hands and face before breaks and immediately after handling product, do not eat, drink, or smoke in the workplace
Appearance: Clear, colorless, odorless, and hygroscopic liquid
Odor: Practically odorless
Boiling Point: 188.2°C (370.8°F)
Melting Point: -59°C (-74°F)
Flash Point: 103°C (217°F) closed cup
Specific Gravity: 1.036 at 20°C (68°F)
Water Solubility: Completely miscible
Vapor Pressure: <1 mm Hg at 20°C
pH: Neutral (6.5-7.5 for 5% solution)
Viscosity: 58.1 mPa·s at 25°C
Partition Coefficient (n-octanol/water): -0.92
Decomposition Temperature: Above 210°C
Evaporation Rate: Negligible (but still present under extreme heat)
Auto-ignition Temperature: 421°C (790°F)
Chemical Stability: Stable under recommended handling and storage conditions
Reactivity: Slight reactivity under normal conditions, can react with strong oxidizers forming hazardous compounds
Hazardous Reactions: Contact with strong acids or bases may lead to violent reactions, risk of hazardous decomposition under fire conditions
Hazardous Decomposition Products: Carbon dioxide, carbon monoxide, possibly other toxic gases under extreme heating
Conditions to Avoid: Excessive heat, sparks, open flame, incompatibles listed above
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Low oral toxicity (LD50 in rats: 20,000 mg/kg), low dermal toxicity (rabbit LD50: 20,800 mg/kg)
Chronic Effects: Prolonged exposure to large amounts may lead to central nervous system effects, lactic acidosis, or kidney/liver effects in extreme overdose
Potential Health Effects: Mild skin and eye irritation, minimal hazard in normal occupational settings
Carcinogenicity: Not listed as carcinogenic by IARC, NTP, OSHA
Sensitization: Not known to be a skin sensitizer
Other Data: Generally recognized as safe (GRAS) when used according to intended food or pharmaceutical purposes
Ecotoxicity: Practically non-toxic to aquatic organisms (LC50 for fish: over 10,000 mg/L)
Persistence and Degradability: Readily biodegradable; decomposes in soil and water through biological action
Bioaccumulative Potential: Very low, does not accumulate in living organisms
Mobility in Soil: High mobility due to water solubility
Other Adverse Effects: Spilled product in large quantities may cause oxygen depletion in aquatic systems due to high biological oxygen demand (BOD)
Disposal Methods: Dispose of as non-hazardous waste in accordance with local, state, and federal regulations
Unused Product: Contact licensed waste disposal contractor for environmentally responsible removal
Contaminated Packaging: Rinse thoroughly before recycling or disposal, follow appropriate guidelines for sanitization and re-use
Sewage Disposal: Do not release significant quantities into sewers or natural waterways without official approval
UN Number: Not regulated as a dangerous good under most transportation regulations (UN, IATA, IMDG, DOT)
Proper Shipping Name: Propylene Glycol
Transport Hazard Class: Not classified as hazardous for transport
Packing Group: Not assigned
Special Precautions: Prevent damage to containers during transport, secure loads to prevent movement and leakage
OSHA: Not listed as hazardous under OSHA Hazard Communication Standard
TSCA: Listed in the United States Toxic Substances Control Act inventory
REACH: Registered under REACH in the European Union
EINECS Number: 200-338-0
SARA Title III: Not subject to reporting under sections 302, 304, 311, 312, or 313
California Proposition 65: Not listed
Other Local Requirements: Check regional and national regulations for possible restrictions or reporting requirements
