© 2026 Nanjing Finechem Holdings Co., Ltd,
All Right Reserved
Product Name: Polyethylene Glycol (PEG)
Chemical Family: Polyether
Chemical Formula: HO(C2H4O)nH
Synonyms: Polyoxyethylene glycol, PEG, Macrogol
CAS Numbers: 25322-68-3 (general), may vary by molecular weight
Recommended Uses: Pharmaceuticals, cosmetics, personal care products, industrial lubricants, food additives, laboratory reagents
Distributor Information: Name, address, and contact of manufacturer or supplier
Emergency Contact: Emergency phone number for immediate assistance
Classification: Not classified as hazardous under GHS (Globally Harmonized System).
Signal Word: None required
Hazard Statements: May cause mild irritation if inhaled, swallowed, or if in contact with skin or eyes.
Precautionary Statements: Avoid inhalation of dust. Avoid contact with eyes and prolonged skin exposure. Wear suitable protective gear during handling.
Route of Exposure: Skin, eyes, inhalation, ingestion
Potential Health Effects: None expected under normal conditions. Mild irritation possible on prolonged exposure.
Environmental Hazards: PEG is considered non-toxic to the environment in standard quantities, but large spills may affect aquatic habitats.
Chemical Name: Polyethylene Glycol
Synonyms: Macrogol, Polyoxyethylene glycol
Concentration Range: 100% (Varies slightly with specification, may contain trace residuals)
CAS Number: 25322-68-3
Impurities: Trace levels of ethylene glycol, diethylene glycol (typical levels within safe regulatory limits)
Eye Contact: Rinse cautiously with clean water for several minutes. Remove contact lenses. Continue rinsing. If redness or discomfort continues, get medical help.
Skin Contact: Wash with soap and plenty of water. Remove contaminated clothing. Seek medical attention for persistent irritation.
Inhalation: If dust or vapor inhaled, move to fresh air. Seek medical attention if symptoms like coughing or shortness of breath appear.
Ingestion: Rinse mouth with water. Do not induce vomiting. Get medical advice if feeling unwell.
Important Info for Doctors: Symptomatic treatment recommended. PEG is considered low toxicity in typical scenarios.
Suitable Extinguishing Media: Water spray, dry chemical, foam, carbon dioxide
Unsuitable Extinguishing Media: High volume water jet directly onto molten substance
Specific Hazards: Heating causes release of vapors; possible emission of toxic fumes like carbon monoxide and carbon dioxide
Protective Equipment for Firefighters: Full protective gear and self-contained breathing apparatus
Fire/Explosion Risk: PEG may burn if exposed to flame; molten product may produce flammable vapors
Special Firefighting Procedures: Avoid inhaling combustion gases, control runoff water to protect environment
Personal Protection: Wear protective gloves, goggles, and suitable clothing to prevent contact
Environmental Precautions: Prevent undiluted product from entering drains or waterways
Containment Methods: Contain and collect spillage using inert absorbent materials such as sand or soil
Clean Up Procedures: Scoop up material into appropriate, labeled containers for disposal. Clean contaminated area with water or industrial detergent.
Reporting Requirements: Comply with regulatory protocols as necessary for bulk releases
Safe Handling Precautions: Handle in well-ventilated areas. Use appropriate PPE to minimize skin and eye contact.
Incompatible Materials: Strong oxidizing agents, acids
Storage Conditions: Store in tightly closed containers, away from direct heat, moisture, and incompatible chemicals. Keep storage area cool and well ventilated.
Hygiene Practices: Wash hands after handling; avoid eating, drinking, or smoking during use.
Storage Class: General chemical storage
Occupational Exposure Limits: No standardized occupational exposure limits established for PEG.
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to maintain airborne levels below recommended exposure limits.
Personal Protective Equipment (PPE):
Appearance: Clear to slightly hazy viscous liquid or white waxy solid (depending on molecular weight)
Odor: Odorless or nearly odorless
Odor Threshold: Not applicable
pH: 4.5 - 7.5 (20% aqueous solution at 20°C)
Melting Point: 4°C to >60°C (varies by molecular weight)
Boiling Point: Exceeds 250°C
Flash Point: >200°C (Pensky-Martens Closed Cup)
Evaporation Rate: Negligible
Flammability: Not classified as flammable
Vapor Pressure: <0.01 mm Hg at 20°C
Relative Density: 1.1 - 1.2 g/cm³
Solubility: Soluble in water, ethanol, glycerol; insoluble in ether
Partition Coefficient (n-octanol/water): log Kow: -1.5 to -2.0
Auto-Ignition Temperature: 370°C
Decomposition Temperature: Not clearly established, thermal decomposition may produce hazardous gases
Viscosity: Varies widely with molecular weight
Chemical Stability: Stable under standard storage and handling conditions
Hazardous Reactions: Not known to polymerize or react dangerously
Conditions to Avoid: Excess heat, sources of ignition, strong oxidizing agents
Incompatible Materials: Strong acids, strong bases, strong oxidizers
Decomposition Products: Carbon oxides, other organic compounds under intense heat
Acute Toxicity: Low oral toxicity (oral LD50 in rats: >20 g/kg)
POTENTIAL HEALTH EFFECTS: May cause mild local irritation or discomfort on prolonged contact with eyes, skin, or if ingested in large amounts. No significant chronic toxicity data for humans.
Skin Corrosion/Irritation: Not classified as skin corrosive or irritant.
Serious Eye Damage/Irritation: May cause mild, transient irritation.
Respiratory or Skin Sensitization: Not sensitizing on skin. Dusts may cause minimal respiratory irritation.
Germ Cell Mutagenicity: Negative in standard tests.
Carcinogenicity: Not classed as carcinogen by IARC, NTP, ACGIH, OSHA.
Reproductive Toxicity: Not expected to impair fertility or development.
Summary of Health Effects: PEG products show very low toxicity profiles, making them widely used in pharmaceutical and cosmetic applications.
Ecotoxicity: Not classified as harmful to aquatic life; LC50 (fish, 96hr): >10,000 mg/L
Persistence and Degradability: PEG is considered readily biodegradable under aerobic conditions.
Bioaccumulation Potential: Low, partition coefficient suggests minimal tendency to bioaccumulate.
Mobility in Soil: High; soluble in water and likely to move in aquatic environments.
Other Adverse Effects: No known endocrine-disruption activity or significant persistence in the environment when used as intended.
Waste Treatment Methods: Dispose of by incineration or at approved waste disposal facility according to local, national, or regional regulations.
Unused Product: Can be treated as non-hazardous waste if no contamination.
Packaging: Rinse and recycle or dispose of in accordance with local regulations.
Precautions: Do not discharge large quantities to sewer systems, surface water, or groundwater.
UN Number: Not regulated for transport by road, sea, or air
UN Proper Shipping Name: Not applicable
Transport Hazard Class: Not classified as hazardous or dangerous for transport
Packing Group: Not applicable
Environmental Hazards: Not considered hazardous to aquatic environments during typical transport
Special Precautions: Avoid high temperatures, prevent container damage during shipping
Regulatory Classification: PEG is not classified as hazardous under OSHA, EU CLP or WHMIS.
Inventory Status: Listed in TSCA (USA), EINECS/ELINCS (EU), DSL (Canada), AICS (Australia)
Safety Standards: Product designed for compliance with applicable industrial, pharmaceutical, and food industry standards
Label Elements: Product labeling should reflect low hazard but provide emergency contacts and handling information
Other Regulations: Not subject to specific REACH restrictions or SARA Title III reporting; food and pharma use grades must comply with relevant FDA or EMA standards
