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Product Name: Picrylsulfonic Acid Solution (5% W/V)
Synonyms: 2,4,6-Trinitrobenzenesulfonic Acid, TNBS Solution
CAS Number: 2508-19-2
Molecular Formula: C6H3N3O9S
Recommended Use: Analytical reagent, protein labeling, immunology research
Supplier: Laboratory chemical distributor or research supply company
Emergency Contact: Refer to local Poison Control Center or supplier’s emergency assistance number
Classification: Oxidizing solid, Acute Toxicity (Oral/Dermal), Skin corrosion/irritation, Serious Eye Damage
Label Elements: Danger symbol (GHS), Signal Word: Danger
Hazard Statements: Causes severe skin burns, causes serious eye damage, may cause respiratory irritation, harmful if swallowed, may cause allergy or asthma symptoms, oxidizer which may intensify fire
Precautionary Statements: Avoid breathing vapors, wear protective gloves, clothing, and eye protection, wash thoroughly after handling, keep away from heat and combustible materials
Main Ingredient: Picrylsulfonic Acid (5% w/v)
Chemical Identity: 2,4,6-Trinitrobenzenesulfonic Acid
Concentration: 5% weight/volume in water
Impurities: None specified
Water Content: Approximately 95%
Inhalation: Remove person to fresh air, seek immediate medical attention if symptoms appear, provide oxygen if breathing is difficult
Skin Contact: Remove contaminated clothing, rinse skin with water for at least 15 minutes, call medical personnel
Eye Contact: Rinse eyes cautiously with water for several minutes, remove contact lenses if present, continue rinsing, seek medical help right away
Ingestion: Rinse mouth, do not induce vomiting, seek medical attention without delay, never give anything by mouth to an unconscious person
Notes for Physicians: Treat as a corrosive and oxidizing agent exposure
Suitable Extinguishing Media: Use water spray, dry chemical, or carbon dioxide, avoid dry combustible material for fighting due to risk of enhanced combustion
Unsuitable Extinguishing Media: Do not use halogenated agents
Specific Hazards: Causes fire intensification, releases toxic gases including nitrogen oxides and sulfur oxides during combustion
Special Protective Equipment for Firefighters: Wear self-contained breathing apparatus, wear protective suit, evacuate area if required
Advice: Approach fire from upwind, cool containers with water spray, control runoff
Personal Precautions: Evacuate nonessential personnel, wear suitable personal protection equipment, prevent contact with skin, eyes, and clothing
Environmental Precautions: Prevent further leakage or spillage, avoid release to the environment, prevent entry into drains or watercourses
Methods for Containment: Contain the spill with inert absorbent material (sand, earth)
Cleaning Up: Scoop absorbed material into a suitable container for disposal, wash spill site after pickup, ventilate area
Safe Handling: Handle only in well-ventilated areas or fume hoods, avoid breathing vapors, avoid all contact with skin and eyes, keep containers tightly closed
Storage Conditions: Store in a cool, dry, well-ventilated place, keep away from direct sunlight, separate from incompatible substances (reducing agents, organic materials, combustibles), store in original container with adequate secondary containment
Incompatibilities: Store away from bases, ammonia, strong reducing agents, metals, flammable substances
Storage Life: Use within indicated shelf life, monitor solution for cloudiness or decomposition
Exposure Limits: No specific OSHA or ACGIH exposure limits, use good industrial hygiene practice
Engineering Controls: Use fume hood, ensure eyewash station and safety shower are accessible
Personal Protective Equipment: Chemical-resistant gloves (nitrile or neoprene), tightly fitting eye protection, face shield, lab coat or chemical-resistant apron, closed footwear
Respiratory Protection: Use appropriate NIOSH-certified respirator if exposure thresholds are exceeded
Appearance: Yellow to orange liquid
Odor: Faint chemical odor
pH: Strongly acidic (typically below 2)
Melting Point/Freezing Point: Not applicable (aqueous solution)
Boiling Point: Similar to water, may favor decomposition before boil
Flash Point: Not determined, not expected to be flammable
Solubility: Miscible in water
Vapor Pressure: Not determined
Density: Approximately 1 g/mL
Reactivity: Strong oxidizer
Chemical Stability: Stable under recommended conditions, unstable near heat, shock, or in presence of reducing agents
Reactivity: Reacts vigorously with reducing materials, metals, strong bases, and organic substances
Hazardous Polymerization: Will not occur
Conditions to Avoid: Excessive heat, exposure to sunlight, physical shock
Hazardous Decomposition Products: Nitrogen oxides, sulfur oxides, toxic fumes
Acute Toxicity: Harmful if swallowed, inhaled, or absorbed through skin; causes burns
Skin Corrosion/Irritation: Severe irritant and corrosive
Serious Eye Damage: Causes permanent eye injury
Respiratory Effects: May cause respiratory irritation, coughing, difficulty breathing
Sensitization: Possible allergen with repeated or prolonged contact
Delayed and Immediate Effects: Blistering, tissue destruction, possible long-term respiratory damage
Aquatic Toxicity: Harmful to aquatic organisms, significant risk of water pollution
Persistence and Degradability: Not readily biodegradable, potential for long-term impact
Bioaccumulation Potential: Not established, avoid environmental release
Mobility in Soil: Expected to move readily in water, risk for groundwater contamination
Other Adverse Effects: Ecotoxic to plants and microorganisms, requires responsible handling
Waste Treatment Methods: Dispose via approved chemical waste contractor, follow all local, state, and national regulations
Unclean Packaging: Rinse containers before disposal or recycling, follow hazardous waste requirements
Special Precautions: Incineration recommended for large quantities, do not dispose in regular drains
UN Number: 3263
Proper Shipping Name: Corrosive Liquid, Basic, Organic, N.O.S. (Picrylsulfonic Acid Solution)
Transport Hazard Class: 8 (Corrosive)
Packing Group: II
Marine Pollutant: Yes
Special Precautions for User: Ensure containers are tightly sealed, use spill-proof secondary containment
OSHA: Classified hazardous under OSHA criteria
SARA Title III: Subject to reporting under Section 311/312
TSCA: Listed on Toxic Substances Control Act Inventory
REACH (EU): Not registered, use for research and development only
Other Regulations: Comply with all federal, state/provincial, and local regulations regarding hazardous materials
