© 2026 Nanjing Finechem Holdings Co., Ltd,
All Right Reserved
Product Name: Phthalaldehyde
Chemical Name: 1,2-Benzenedicarboxaldehyde
Synonyms: O-Phthalaldehyde, OPA
CAS Number: 643-79-8
Molecular Formula: C8H6O2
Molecular Weight: 134.14 g/mol
Recommended Use: Disinfectant, laboratory reagent, chemical intermediate
Supplier: Information provided by manufacturer or distributor
Emergency Telephone: Listed contact for spills, accidents, or exposures
Classification: Acute toxicity (oral, dermal), Serious eye damage/eye irritation, Skin irritation, Sensitization
GHS Label Elements: Danger symbol, Hazard statements for toxic if swallowed, causes serious eye damage, may cause allergic skin reactions
Hazard Statements: Harmful if swallowed, causes eye damage, skin sensitizer
Precautionary Statements: Avoid breathing dust, wash skin thoroughly after handling, wear protective gloves, avoid release to environment
Routes of Exposure: Inhalation, ingestion, skin contact, eye contact
Symptoms of Exposure: Eye pain, skin irritation, breathing difficulty, allergic dermatitis, nausea, vomiting
Chemical Name: Phthalaldehyde
Common Name: O-Phthalaldehyde
EC Number: 211-402-2
Concentration: 99% or higher by weight
Impurities: Trace organic solvents, possible by-products depending on synthesis
Stabilizers/Additives: None typically present in pure form
Inhalation: Move person to fresh air, keep at rest, provide oxygen if breathing difficult, seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, wash affected skin with soap and water, consult health provider for irritation or allergic reaction
Eye Contact: Rinse cautiously with water for at least 15 minutes, remove contact lenses, seek immediate medical help
Ingestion: Rinse mouth, do not induce vomiting, seek prompt medical attention
Acute Symptoms: May cause severe eye irritation or burns, respiratory distress, allergic reaction, nausea
Delayed Effects: Sensitization of skin, long-term respiratory impact with repeated exposure
Suitable Extinguishing Media: Dry chemical, foam, carbon dioxide, water spray in fine mist
Unsuitable Media: Direct stream of water may spread fire
Hazards from Combustion: Carbon monoxide, carbon dioxide, irritating aldehyde fumes
Protective Equipment: Self-contained breathing apparatus, full protective gear
Firefighting Advice: Use water to keep fire-exposed containers cool, avoid breathing combustion products, evacuate area if large fire
Special Procedures: Dike runoff from fire control to prevent entry into waterways
Personal Precautions: Wear chemical resistant gloves, safety goggles, respiratory protection in case of dust or vapors
Environmental Precautions: Prevent spill from entering drains or waterways, inform authorities in case of environmental contamination
Cleanup Methods: Absorb spill with inert material, place in chemical waste container, ventilate affected area
Small Spills: Scoop or wipe up for proper disposal, clean area with detergent
Large Spills: Dike area, recover material, contact hazardous waste disposal service
Decontamination: Use water and mild soap to clean surfaces after material removal
Handling: Use only with adequate ventilation, avoid contact with skin and eyes, prevent release of dust, keep containers tightly closed, wash hands after handling chemical
Technical Measures: Use local exhaust ventilation, avoid creating aerosols, always transfer in fume hood if possible
Storage Conditions: Keep in cool, dry, well-ventilated area, away from heat and ignition sources, protect from sunlight
Compatible Materials: Store in original container, avoid strong acids, oxidizers, bases
Incompatible Materials: Strong oxidizing agents, reducing agents, acids
Special Precautions: Keep out of reach of children, store away from food and animal feed
Engineering Controls: Use mechanical exhaust, fume hoods, eyewash station and safety shower available in work area
Exposure Limits: No occupational exposure limits established; minimize all unnecessary exposure
Personal Protective Equipment: Chemical resistant gloves, goggles, lab coat, respiratory protection in low ventilation areas
Hygiene Measures: Wash hands before breaks and at end of workday, do not eat, drink, or smoke during use
Environmental Controls: Prevent chemical from spreading into natural waterways, contain and treat all waste and runoff
Appearance: White to pale yellow crystalline solid
Odor: Mild, pungent aromatic
Odor Threshold: Not determined
pH: Not available in solid form, acidic in solution
Melting Point: 54 – 56°C (129 – 133°F)
Boiling Point: Decomposes before boiling
Flash Point: Approximately 113°C (235°F)
Evaporation Rate: Not applicable
Flammability: May be combustible at high temperature
Vapor Pressure: Low at room temperature
Vapor Density: Not available
Density: 1.2 g/cm³ at 20°C
Solubility: Slightly soluble in water, soluble in alcohols and other organic solvents
Partition Coefficient: log Kow 0.6 (estimated)
Auto-ignition Temperature: 400°C (752°F)
Decomposition Temperature: Above 130°C (266°F), emits toxic fumes
Viscosity: Not applicable in solid form
Chemical Stability: Stable under normal storage and handling conditions, sensitive to heat and moisture
Reactivity: Reacts with strong oxidizers, acids, bases, possible exothermic decomposition
Hazardous Reactions: May polymerize or decompose when exposed to high temperatures or incompatible chemicals
Conditions to Avoid: Exposure to heat, sources of ignition, direct sunlight, moisture
Incompatible Materials: Strong acids, strong oxidizing agents, strong bases, reducing agents
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, irritating aldehyde vapors
Acute Toxicity: Oral LD50 (rat) 510 mg/kg; inhalation LC50 not determined
Skin Corrosion/Irritation: May cause severe skin irritation, allergic reactions in susceptible individuals
Serious Eye Damage/Irritation: Causes severe eye burns, risk of permanent injury
Respiratory or Skin Sensitization: Can produce respiratory discomfort, may trigger skin sensitization
Chronic Effects: Repeated exposure linked to allergic contact dermatitis
Target Organs: Eyes, skin, respiratory system, mucous membranes
Carcinogenicity: Not classified as a carcinogen by IARC, NTP, or OSHA
Mutagenicity: No evidence in currently available studies
Reproductive Toxicity: No data indicating reproductive effects
Other Toxicological Data: May cause gastrointestinal and systemic toxicity if ingested in large quantity
Ecotoxicity: Harmful to aquatic life; low concentrations may impact invertebrate populations, algae, and fish
Persistence and Degradability: Moderately persistent, slow biodegradation in aquatic environments
Bioaccumulative Potential: Low, based on log Kow
Mobility in Soil: Expected moderate mobility, some adherence to organic solids
Other Adverse Effects: May cause oxygen depletion in water due to chemical oxygen demand
Aquatic Toxicity Data: EC50 (Daphnia magna) 1.5 mg/L/48h; LC50 (rainbow trout) 6.7 mg/L/96h
Waste Treatment Methods: Chemical waste must be collected and disposed by licensed disposal company, do not dump into sewers
Container Disposal: Rinse prior to disposal, puncture or crush under authority guidelines, do not reuse
Disposal Restrictions: Adhere to regional and local regulations, do not release to environment
Special Handling: Scientists and waste handlers should follow all personal protection standards, document disposal compliance
Hazardous Waste Code: Consult local environmental authority for applicable classification and recommendation
UN Number: UN 2929
Proper Shipping Name: Toxic solid, organic, n.o.s. (contains Phthalaldehyde)
Transport Class: 6.1 (Toxic substances)
Packing Group: II (substances presenting medium danger)
Hazard Label: Toxic
Marine Pollutant: Yes, avoid release to water
Transport Precautions: Seal in secondary containment, avoid shaking, keep cool and dry, emergency contact info enclosed
Other Requirements: Comply with DOT, IATA, IMDG for international, national shipments
EU Regulations: Complies with REACH registration requirements and CLP classification, label requirements covered under Regulation (EC) No 1272/2008
US Regulations: Listed in TSCA (Toxic Substances Control Act) inventory, regulated under OSHA Hazard Communication Standard
Right-To-Know Reporting: States may list phthalaldehyde under local hazardous chemical statutes
Other International Regulations: Covered under Canadian WHMIS as toxic material, Global Harmonized System (GHS) classification applicable
Registered Use: Registered for use in hospitals and laboratories under certain biocidal and disinfectant regulations
Labeling Requirements: GHS label with hazard pictograms and protective phrases in readable type and local language
