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Product Name: Phenylhydrazine Hydrochloride
Chemical Formula: C6H5NHNH2·HCl
CAS Number: 59-88-1
Synonyms: Phenylhydrazinium chloride, Hydrazinobenzene hydrochloride
Recommended Use: Laboratory chemicals, organic synthesis, analytical reagent
Manufacturer/Supplier Contact: Safety and compliance office, industrial supplier chain, regulatory affairs professional
Emergency Contact: Company safety officer, poison control center, emergency health line
Classification: Acute Toxicity Oral (Category 3), Skin Corrosion/Irritation (Category 2), Eye Damage/Irritation (Category 2A), Germ Cell Mutagenicity (Category 2), Carcinogenicity (Category 2)
Label Elements: Skull and crossbones pictogram, exclamation mark, health hazard icon
Signal Word: Danger
Hazard Statements: Toxic if swallowed, may cause cancer, suspected of causing genetic defects, causes skin irritation, causes serious eye irritation
Precautionary Statements: Avoid breathing dust or vapors, wear protective gloves, wash hands thoroughly after handling, do not eat or drink while using, store locked up
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Chemical Name: Phenylhydrazine Hydrochloride
Concentration: Pure substance
CAS Number: 59-88-1
Impurities: Trace level manufacturing by-products possible, main ingredient accounts for essentially all content
Identification Numbers: EC Number: 200-446-1, UN Number: 2811
General Advice: Remove victim away from exposure, ensure fresh air, seek immediate medical attention
Skin Contact: Remove contaminated clothing, rinse skin with abundant water and mild soap, seek medical evaluation for persistent symptoms
Eye Contact: Flush with plenty of water for at least 15 minutes, maintain eyelids open, contact an ophthalmologist
Inhalation: Move to fresh air, apply artificial respiration if not breathing, seek urgent care for shortness of breath or persistent cough
Ingestion: Rinse mouth with water, do not induce vomiting, call medical services and advise on substance involved
Self-protection of First Responder: Use protective gloves, mask, and goggles
Suitable Extinguishing Media: Water spray, dry powder, foam, carbon dioxide
Unsuitable Media: Avoid direct water jets on substance
Specific Hazards: Emits toxic nitrogen oxides, hydrochloric acid, and carbon monoxide under combustion
Advice for Firefighters: Wear full protective suit and self-contained breathing apparatus, isolate hazardous area, prevent runoff into drains
Combustion Products: Toxic, corrosive fumes possible during thermal decomposition
Personal Precautions: Evacuate area, avoid dust generation, ventilate space, use personal protective equipment (goggles, gloves, masks)
Environmental Precautions: Do not allow chemical to reach sewage or water bodies, contain spill to avoid spreading
Clean-Up Methods: Collect with non-combustible absorbent materials (e.g., sand, diatomaceous earth), sweep up, place in containers with secure lids for proper disposal
Other Instructions: Decontaminate area with water after cleanup, dispose of all materials as hazardous chemical waste
Handling: Guard against inhalation and direct skin contact, handle in fume hood or ventilated area, use proper gloves and safety goggles, avoid eating or drinking during use, ensure chemicals are labeled correctly
Storage: Store in tightly sealed containers, keep dry and in a cool, well-ventilated place, separate from incompatible substances (strong oxidizers, acids), prevent access by unauthorized personnel, maintain temperature control to prevent decomposition
Special Instructions: Regular inspection of chemical stocks, periodic reassessment of storage conditions, employ leak and spill containment
Engineering Controls: Use fume hoods, mechanical exhaust, and appropriate ventilation systems
Exposure Limits: Local legal occupational exposure limit values may apply (USA OSHA: 0.01 ppm as TWA for hydrazines as reference)
Personal Protective Equipment: Wear nitrile or butyl gloves, laboratory coat, chemical splash goggles, and, during large-scale use, respirators with appropriate filters
Hygiene Measures: Wash hands and face before breaks and at the end of work, avoid contaminated clothing
Appearance: White to off-white crystalline powder
Odor: Weak, faintly aromatic
Molecular Weight: 144.58 g/mol
Melting Point: 240°C (decomposes)
Solubility: Soluble in water, slightly soluble in ethanol
Density: Approximately 1.3 g/cm3 (at 20°C)
Boiling Point: Not applicable; decomposes before boiling
pH: Acidic aqueous solution
Vapor Pressure: Negligible at room temperature
Flash Point: Not applicable (nonvolatile solid)
Partition Coefficient: log Pow: Not available
Chemical Stability: Stable under recommended storage conditions
Reactivity: Reacts violently with strong oxidizers, strong acids
Hazardous Reactions: Risk of explosions and toxic gas formation with oxidants, contact with acids liberates toxic fumes
Decomposition Products: Nitrogen oxides, hydrochloric acid, carbon monoxide when heated or combusted
Conditions to Avoid: Moisture, heat, incompatibles, exposure to sunlight
Acute Toxicity: Harmful if swallowed or inhaled, LD50 (oral, rat): 55 mg/kg
Skin Corrosion/Irritation: Causes moderate to severe irritation
Eye Damage/Irritation: Causes moderate to severe eye irritation
Carcinogenicity: Animal studies indicate possible cancer risk, listed as a group 2B carcinogen by IARC
Mutagenicity: Laboratory studies document genetic mutation risks
Sensitization: No reliable evidence regarding skin sensitization
Chronic Effects: Blood disorders after prolonged exposure, potential damage to liver and kidneys
Target Organs: Liver, kidneys, blood-forming organs
Additional Information: Vapors and dusts require careful control and monitoring during laboratory and industrial use
Environmental Toxicity: Harmful to aquatic organisms, long-lasting adverse effects
Persistence and Degradability: Expected to biodegrade slowly, but persistent in soil and sediments
Bioaccumulative Potential: Not expected to bioaccumulate significantly in aquatic organisms
Mobility in Soil: Mobile in moist environments, may leach into groundwater without proper containment
Other Hazards: Potential impact on wastewater microbiota, risks to drinking water sources if mismanaged
Waste Treatment Methods: Collect in clearly labeled, sealed hazardous waste containers, do not pour into drains or municipal waste
Disposal of Product: Ship to licensed hazardous waste processor, conform input to local regulations
Contaminated Packaging: Triple rinse glassware or plasticware, dispose via hazardous waste protocols
Environmental Cautions: Prevent direct release to surface or underground water
Other Recommendations: Consult state and federal regulations for chemical return and cradle-to-grave tracking
UN Number: UN 2811
Proper Shipping Name: Toxic solid, organic, n.o.s. (includes Phenylhydrazine Hydrochloride)
Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Labels: Toxic hazard label required
Special Transport Precautions: Keep away from food, feedstuffs, and incompatible goods; prevent package breakage or leakage; transport only in labeled and certified containers
Transport Regulations: Comply with DOT, IATA, IMDG rules
US Regulations: TSCA (Toxic Substances Control Act): Listed, SARA Title III reporting required for certain quantities, OSHA hazard chemical
European Regulations: REACH registration required, CLP hazard labeling, workplace exposure limits set under EU directives
Global Regulations: Covered by UN Recommendations on the Transport of Dangerous Goods, GHS compliant classification
Other Requirements: Maintain safety documentation accessible to all users, update risk assessments regularly, employee hazard communication and regular training
