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Product Name: Phenoxyethanol
Chemical Formula: C8H10O2
Chemical Name: 2-Phenoxyethanol
CAS Number: 122-99-6
Synonyms: Ethylene glycol monophenyl ether, Glycol ether
Recommended Use: Preservative in cosmetics, solvent in inks and dyes, stabilizer in pharmaceuticals
Supplier Information: Name, address, and emergency phone numbers from the manufacturer or distributor
Hazard Classification: Acute toxicity (oral, dermal), skin and eye irritation
Hazard Statements: Harmful if swallowed or in contact with skin, causes serious eye irritation
Pictograms: Exclamation mark
Signal Word: Warning
Precautionary Statements: Avoid contact with skin and eyes, do not eat, drink, or smoke while handling, wash hands after handling
Potential Health Effects: Inhalation leads to cough and sore throat; skin contact causes redness; eye exposure brings irritation and pain; ingestion may result in abdominal pain
NFPA Rating: Health: 2, Flammability: 1, Reactivity: 0
Chemical: 2-Phenoxyethanol
Concentration: 99-100%
CAS Number: 122-99-6
Other Components: No significant impurities relevant to classification
Inhalation: Remove to fresh air, seek medical attention for persistent symptoms
Skin Contact: Take off contaminated clothing, wash skin immediately with soap and water, seek medical advice for ongoing irritation
Eye Contact: Rinse with plenty of water for at least 15 minutes, remove contact lenses, keep eye wide open, consult medical care if irritation persists
Ingestion: Rinse mouth with water, do not induce vomiting, get medical help
Most Important Symptoms: Eye irritation, skin redness, headache, dizziness if inhaled in large quantities
Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical, carbon dioxide
Unsuitable Extinguishing Media: Direct water jet
Special Exposure Hazards: Releases toxic fumes under fire conditions, such as carbon monoxide and carbon dioxide
Protective Equipment for Firefighters: Self-contained breathing apparatus, full protective suit
Specific Methods: Keep containers cool with water spray, evacuate area if needed
Personal Precautions: Use protective gloves, goggles, and clothing, ventilate area, avoid breathing vapors
Environmental Precautions: Prevent run-off into sewers or water sources, notify authorities if entry occurs
Containment Methods: Absorb with sand, earth, or inert material, shovel into appropriate container
Cleanup Procedures: Wash the spill area thoroughly after collection, dispose of collected materials according to local regulations
Handling: Use with adequate ventilation, avoid contact with skin and eyes, do not breathe vapor or spray, keep containers tightly closed
Storage: Store in cool, dry, well-ventilated area, keep away from incompatible substances such as strong oxidizers and acids, avoid temperature extremes, keep containers well-sealed and upright, use only non-sparking tools
Control Parameters: No established OSHA or ACGIH limits; handle based on best industrial hygiene practices
Engineering Measures: Use local exhaust or general room ventilation
Personal Protective Equipment: Chemical-resistant gloves (nitrile or neoprene), safety goggles, protective clothing, use of respirator recommended for high vapor concentrations
Hygiene Measures: Wash hands after handling, remove contaminated clothing, do not eat or drink while using the material
Appearance: Clear, colorless to slightly yellow oily liquid
Odor: Faint rose-like, pleasant odor
Odor Threshold: Not available
pH: 6–7 (at 20°C, 10g/L water)
Melting Point/Freezing Point: -2°C
Boiling Point: 245°C
Flash Point: 121°C (closed cup)
Evaporation Rate: Not available
Flammability: Not highly flammable
Vapor Pressure: 0.11 mmHg at 25°C
Vapor Density: 5.1 (air = 1)
Relative Density: 1.105 g/cm³ at 20°C
Solubility: Slightly soluble in water, soluble in alcohols and organic solvents
Partition Coefficient (log Kow): 1.2
Auto-Ignition Temperature: 470°C
Decomposition Temperature: Not specified
Viscosity: 17 mPa.s at 20°C
Chemical Stability: Stable under recommended storage and handling conditions
Possibility of Hazardous Reactions: No hazardous polymerization
Conditions to Avoid: High temperatures, open flames, sparks
Incompatible Materials: Strong oxidizers, acids, alkali metals
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, phenol under thermal decomposition
Acute Toxicity: Oral LD50 (rat): 1260 mg/kg; Dermal LD50 (rabbit): 5000 mg/kg
Skin Corrosion/Irritation: Mildly irritating to skin
Eye Damage/Irritation: Causes serious eye irritation
Respiratory Sensitization: Not classified
Skin Sensitization: Not classified
Germ Cell Mutagenicity: Not considered mutagenic
Carcinogenicity: Not classified as a carcinogen by IARC, NTP, or OSHA
Reproductive Toxicity: Studies show low reproductive toxicity
STOT – Single Exposure: Inhalation may cause drowsiness or dizziness
STOT – Repeated Exposure: Not classified
Other Information: Prolonged or repeated exposure can cause dermatitis, headache, and central nervous system effects
Ecotoxicity: Toxic to aquatic organisms at high concentrations
Aquatic Toxicity: LC50 (fish, 96h): 460 mg/L (Pimephales promelas), EC50 (daphnia, 48h): 500 mg/L
Persistence and Degradability: Readily biodegradable
Bioaccumulative Potential: Low log Kow (1.2), low potential for bioaccumulation
Mobility in Soil: Expected to have moderate mobility
Other Adverse Effects: No known significant effects or hazards
Waste Disposal Methods: Dispose of by incineration or according to local, regional, national, and international regulations
Contaminated Packaging: Empty containers retain product residue, do not reuse, dispose via authorized waste disposal contractor
Precautions: Avoid release to the environment, comply with all applicable disposal regulations
UN Number: Not regulated by DOT, IMDG, IATA
UN Proper Shipping Name: Not applicable
Transport Hazard Class: Not classified as hazardous
Packing Group: Not assigned
Environmental Hazards: Not applicable
Special Precautions for User: Prevent spillage, avoid rough handling containers during transport
TSCA Inventory: Listed
REACH (EU): Registered under EC 1907/2006
OSHA Hazards: Combustible liquid, target organ effect
WHMIS Classification: D2B (toxic material causing other toxic effects)
SARA Title III Sections 302, 304, 313: Not listed
DSL/NDSL (Canada): Listed
Other Regulations: Meets safety and environmental requirements in most major markets for use in personal care and cleaning products
