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Product Name: Percoll Silice Coloidal
Chemical Family: Colloidal Silica Suspension
Synonyms: Colloidal silicate, silica colloidal solution
Supplier Details: Refer to packaging for name, address, and contact phone of manufacturer or distributor
Use: Laboratory separation medium, density gradient centrifugation, biological sample preparation
Emergency Contact: Refer to packaging or national emergency contact resource
CAS Number: 7631-86-9 (Colloidal Silica), 7732-18-5 (Water)
Classification: Non-hazardous under most global GHS definitions, mild irritant to eyes and skin
GHS Label Elements: Not classified as hazardous, precautionary eye and skin warning recommended
Health Effects: Mild redness or irritation if splashed on skin or eyes, not considered toxic by ingestion or inhalation under normal use
Signal Word: None required, though avoiding unnecessary exposure is recommended
Precaution: Prevent contact with eyes and prolonged skin exposure, ensure adequate ventilation during use
Pictograms: Not typically required
Component: Colloidal Silica
Chemical Formula: SiO2 in H2O
Concentration: 15-50% depending on manufacturer and grade
Other Ingredients: Deionized Water
Impurities: Trace stabilizers present in some batches, documentation from supplier will specify exact identity and concentration
Toxic Components: None present in concentrations known to be harmful under normal use
Inhalation: Move person to fresh air if signs of breathing discomfort appear, seek medical attention if symptoms persist
Skin Contact: Wash skin thoroughly with soap and water, remove contaminated clothing, consult a physician if irritation develops
Eye Contact: Rinse carefully with water for at least 15 minutes, remove contact lenses after first rinse if present, seek medical advice if irritation persists
Ingestion: Rinse mouth with water, drink water to dilute, do not induce vomiting, seek medical attention if unwell
Note to Physician: Treat symptomatically, there is no known specific antidote
Flammability: Non-flammable, does not sustain combustion
Suitable Extinguishing Media: Use extinguishing media appropriate for surrounding fire, water spray, foam, carbon dioxide, dry powder
Hazardous Combustion Products: None expected, product does not burn
Protective Equipment: Firefighters should wear self-contained breathing apparatus and standard protective clothing to avoid exposure to decomposition products in the event of adjacent fire
Special Procedures: Cool containers with water spray to prevent pressure build-up if adjacent to fire
Personal Precautions: Wear suitable protective gloves and goggles, prevent spills from contacting skin and eyes
Environmental Precautions: Prevent release into drains and waterways, large spills may require damming and containment
Methods for Clean-Up: Absorb with inert material (e.g., sand, earth), collect residue into suitable containers for disposal, flush remaining area with water
Disposal: Place all waste and cleanup materials in sealed, labeled containers for proper disposal according to local regulations
Handling: Avoid direct contact with skin and eyes, wear protective gloves, practice good laboratory hygiene, use in well-ventilated areas
Storage Conditions: Store in tightly closed original containers in a cool, dry, well-ventilated place, keep away from incompatible materials and direct sunlight
Shelf Life: Product stability decreases if container is opened for prolonged periods; check expiration dates
Special Storage Needs: Protect from freezing and excessive heat which can destabilize suspension
Exposure Limits: No workplace exposure limits established for colloidal silica or water
Engineering Controls: Ensure adequate room ventilation, use local exhaust where large quantities are handled
Personal Protective Equipment: Safety goggles or face shield, chemical-resistant gloves (such as nitrile), laboratory coat
Hygiene Measures: Wash hands thoroughly after handling, do not eat, drink, or smoke while using
Respiratory Protection: Not usually required for solution, use dust mask if dried material is present or handling generates aerosols
Appearance: Translucent or white suspension
Odor: Odorless
Boiling Point: Approx. 100°C
Melting Point: Not applicable (aqueous suspension)
Vapor Pressure: As for water, negligible at room temperature
pH: 8-10 depending on product grade
Solubility: Miscible in water
Density: Typically 1.1–1.2 g/mL at 20°C
Decomposition Temperature: Stable below 100°C
Particle Size: 10-100 nm typical for silica component
Viscosity: Slightly more viscous than water
Physical State: Liquid
Chemical Stability: Stable under normal storage and use conditions
Reactivity: Non-reactive with most common materials
Possibility of Hazardous Reactions: Will not polymerize or generate hazardous products during use
Conditions to Avoid: Freezing, extreme heat, acidic or basic contaminants
Incompatible Materials: Strong acids, strong bases, hydrofluoric acid
Hazardous Decomposition Products: None known under normal conditions
Routes of Exposure: Skin and eye contact, accidental ingestion or inhalation of dried residue
Acute Toxicity: Not expected to cause toxic effects, LD50 (oral, rat) > 5000 mg/kg
Skin Corrosion/Irritation: Mild or transient irritation possible
Eye Damage/Irritation: Mild irritant potential, flush promptly
Sensitization: Not expected to cause allergic skin reactions
Chronic Toxicity: No known long-term hazards, no evidence of carcinogenicity, mutagenicity, or reproductive toxicity from colloidal silica at typical concentrations
Additional Notes: Prolonged or repeated contact may dry skin
Toxicity to Aquatic Life: Low environmental hazard, not expected to bioaccumulate or be toxic to aquatic organisms
Mobility in Soil: Colloidal silica disperses in water, low potential for runoff contamination due to inert nature
Persistence and Degradability: Silica will remain in environment as inert mineral, no rapid breakdown
Bioaccumulation: Not expected to bioaccumulate
Additional Environmental Hazards: Large spills could increase suspended solids in water, possibly affecting aquatic filtering organisms
Methods: Dispose as non-hazardous laboratory waste unless contaminated with hazardous materials, follow local, regional, and national regulations
Packaging: Place material and cleanup residues in sealed appropriate containers
Sewage Disposal: Small quantities can be flushed to drain with plenty of water unless prohibited by local regulations
Special Precautions: Avoid disposal into natural waterways or storm drains in large quantities
UN Number: Not regulated by international or domestic transport codes
Proper Shipping Name: Not classified as dangerous goods
Hazard Class: Non-hazardous
Packing Group: Not assigned
Environmental Hazard: Not a marine pollutant
Special Precautions for User: Protect containers from physical damage and secure loads for transport
Labeling: Not hazardous under most jurisdictions including OSHA, WHMIS, EU CLP
Inventory Listing: Product and components listed or exempted on TSCA (USA), DSL (Canada), EINECS (EU)
REACH Status: Silica registered under REACH for industrial uses
Other Regulations: Observe workplace exposure controls as required by country, provide SDS to users as per hazardous chemical regulations
Safety Assessment: Product considered safe for intended uses, specific regulatory restrictions may depend on country or state
