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Product: Partisil 10 SCX HPLC Column
Usage: HPLC analysis, cation exchange separations
Main Materials: Silica base, functionalized with sulfonic acid groups for strong cation exchange
Form: Packed column, solid phase present as powder encased in glass or steel tubing
Color/Odor: Fine powder, usually white or off-white, no noticeable odor in routine use
Physical Risk: The silica packing can create dust if tube breaks; dust inhalation causes mild respiratory discomfort
Chemical Risk: Sulfonic acid groups may irritate eyes and skin on contact; no acute toxicity in typical laboratory handling
Chronic Risk: Prolonged overexposure to silica dust links to respiratory disease, but normal use in column format keeps risk low
Fire/Explosion Risk: Non-flammable packing; risk arises from solvents used, not column itself
Principal Substance: Amorphous silica
Functional Groups: Sulfonic acid moieties bound to silica
Impurities: None anticipated that pose known hazards at usual concentrations
Carrier/Matrix: Steel or glass column housing
Inhalation: Move affected person to fresh air, seek medical attention if symptoms persist
Eye Contact: Rinse eyes with water for several minutes, remove contact lenses, consult a doctor if irritation continues
Skin Contact: Wash area with soap and water, remove contaminated clothing
Ingestion: Rinse mouth, seek medical help, do not induce vomiting
Suitable Extinguishing Media: Use dry chemical, foam, carbon dioxide for fires involving column solvents
Combustion Products: Heated metal or glass columns may fracture, avoid inhaling combustion fumes from associated solvent fires
Protection for Firefighters: Respiratory protection required if fire involves organic solvents
Personal Precautions: If the column breaks, avoid breathing dust, ventilate area
Cleanup Procedures: Sweep up silica powder cautiously with minimal dust generation, transfer to closed container
Spill of Solvents: Use absorbent material, ventilate area well, wear gloves and goggles
Handling: Store column upright, avoid mechanical shock, handle with gloves to prevent skin contact
Storage: Keep in cool, dry area away from incompatible chemicals and direct sunlight
Incompatibles: Strong bases and hydrofluoric acid attack silica
Engineering Measures: Work in well-ventilated room, use fume hood for packing or disposing bulk powder
Personal Protection: Wear lab coat, safety glasses, gloves during handling or disposal
Exposure Limits: OSHA sets Permissible Exposure Limits for respirable silica dust; in routine column use, these limits are not approached
Appearance: White or off-white powder packed in rigid column
Odor: None in normal conditions
Melting Point: Decomposition above 1600°C
Solubility: Insoluble in water and solvents
Reactivity: Stable at standard temperature and pressure
Chemical Stability: Stable under typical lab conditions
Hazardous Reactions: Avoid strong bases and hydrofluoric acid, which degrade silica
Decomposition Products: None significant under lab use
Inhalation: Bulk dust inhalation causes lung irritation; unlikely during intact column use
Eye/Skin Contact: Direct contact irritating; not a typical risk except during fracture or repacking
Ingestion: Not intended, may cause mild GI upset
Carcinogenicity: Crystalline, not amorphous, silica classified as respiratory carcinogen; not present in this material
Persistence: Silica and sulfonic groups are stable, non-biodegradable
Environmental Impact: Minimal at lab scale; bulk dumping not recommended since fine powders affect soil structure
Aquatic Risk: Insoluble, so low mobility in water
Preferred Disposal: Dispose in accordance with local regulations as inert laboratory waste
Special Precautions: Avoid generating dust during handling or disposal
Reuse/Recycle: Possible in some facilities for non-contaminated columns
Transport Classification: Non-hazardous for ground, sea, or air freight
Packing Recommendations: Prevent crushing of column, avoid damage that releases powder
Labeling: Standard chemical hazard labels for silica recommended if bulk powder encountered
Relevant Regulations: OSHA chemical hygiene standard for lab work, EPA waste guidelines for silica-based materials
