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Substance Name: Naringin
Chemical Formula: C27H32O14
Appearance: White to pale yellow powder
Odor: Faint citrus scent
Primary Sources: Grapefruit, citrus fruits
Common Uses: Food additive, flavor enhancer, nutraceutical applications, research reagent
CAS Number: 10236-47-2
Physical Hazards: Dust can form explosive mixtures with air in rare cases
Health Hazards: May cause irritation to skin, eyes, and respiratory tract on prolonged or repeated exposure
Environment Hazards: No known acute environmental risks; improper disposal could impact aquatic life
Routes of Exposure: Inhalation, ingestion, skin or eye contact
Ingredient: Naringin
Concentration: Typically above 95% in purified products used for industrial and research purposes
Impurities: Trace amounts of other citrus flavonoids possible present depending on source extraction methods
Inhalation: Move to fresh air right away; seek medical attention if coughing or breathing problems linger
Skin Contact: Rinse thoroughly with water; remove contaminated clothing if large spill occurs; irritation may need a doctor’s care
Eye Contact: Rinse immediately and deeply with clean water for several minutes; medical help for persistent discomfort
Ingestion: Rinse mouth if swallowed; never force vomiting; consult medical professional if symptoms develop
Suitable Extinguishing Materials: Dry chemical, carbon dioxide, alcohol-resistant foam, or water spray
Fire Hazards: Fine dust can ignite in confined areas
Protective Equipment: Standard firefighting gear plus face and eye protection; avoid inhaling smoke
Combustion Products: Carbon monoxide, carbon dioxide, possible organic fumes
Firefighting Actions: Control dust; maintain good ventilation
Spill Containment: Sweep up while avoiding dust generation; ventilate area well
Clean-Up Methods: Use non-sparking tools, collect in suitable container for disposal
Personal Precautions: Wear protective gloves, goggles, and dust respiratory mask
Environmental Precautions: Prevent large releases from entering waterways or soil
Handling: Minimize dust; work in ventilated spaces; wash hands after handling
Storage Conditions: Keep in airtight containers; store in cool, dry place, away from direct light and incompatible substances
Storage Location: Dedicated, clearly labeled area recommended for powders
Incompatible Materials: Strong acids, strong bases, oxidizing agents
Engineering Controls: Ventilation and local exhaust especially in powder-handling zones
Personal Protection: NIOSH-approved dust masks or respirators for dusty environments; protective gloves and goggles for frequent handlers
Hygiene Practices: Wash hands thoroughly after use; avoid eating and drinking on the job; change soiled clothing promptly
Occupational Limits: No established government exposure limits; control dust levels through good practices
Physical State: Solid powder
Color: White to pale yellow
Odor: Mild, faintly citrus
Melting Point: Approximately 240°C (decomposes)
Solubility: Slightly soluble in water; more soluble in ethanol, methanol, and DMSO
Molecular Weight: 580.54 g/mol
Boiling Point: Not applicable (decomposes)
Density: Not readily available in public literature; generally fits powder density profiles
Stability: Stable under normal temperature and dry conditions
Reactivity: Does not react strongly with common substances
Condition to Avoid: Moisture, heat, exposure to strong acids or bases
Hazardous Decomposition: Burning releases carbon oxides and organic fumes
Polymerization: Not known to occur
Acutely Toxic: Not considered acutely toxic in small quantities commonly handled
Potential Effects: High doses could cause gastrointestinal upset if consumed; dust may irritate respiratory tract
Skin/Eye Contact: May cause mild irritation or dryness
Carcinogenicity: Not classified as a carcinogen by major regulatory bodies
Chronic Exposure: No evidence for long-term toxicity at low levels; occupational exposure should be kept minimal
Aquatic Impact: High concentrations may be harmful to aquatic organisms if released in bulk amounts
Persistence: Flavonoids like naringin can degrade slowly in soil and water environments
Bioaccumulation: Not known to bioaccumulate significantly
Environmental Release Advice: Avoid large uncontrolled releases; maintain good waste containment
Waste Handling: Collect and seal unwanted powder in compatible containers
Preferred Disposal: Incinerate under controlled conditions following local legislation
Do Not: Discard into sewers, waterways, or open soil
Regulatory Review: Check for local and national rules governing disposal of chemical substances containing organic compounds
Class: Non-hazardous for land, air, and sea transport under standard regulations in most regions
Packing and Labeling: Use sealed, labeled containers to prevent accidental release and ensure correct identification
Spillage Risk: Mainly dust nuisance if packaging damaged in transit
Global Regulation: No major restrictions in food, supplement, and chemical markets when purity meets safety thresholds
Labeling Advice: Contents, hazard warnings, and handling guidance should be clear
Worker Protection: Standard chemical safety rules for laboratory and industrial materials apply
SDS Availability: Employers should keep accessible documents for workplace safety reviews and employee training
