© 2026 Nanjing Finechem Holdings Co., Ltd,
All Right Reserved
Chemical Name: N,N'-Methylenebisacrylamide
Synonyms: MBA, Bis-acrylamide, N,N'-Methylenedimethacrylamide
CAS Number: 110-26-9
Recommended Use: Laboratory chemical, cross-linking reagent in polyacrylamide gel electrophoresis
Supplier: Refer to local distributor information
Emergency Contact: National Poison Control Center
Classification: Acute Toxicity Oral Category 4, Eye Irritation Category 2A, Skin Sensitizer Category 1
Signal Word: Warning
Hazard Statements: Harmful if swallowed. Causes serious eye irritation. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction.
Pictograms: Exclamation mark, Health hazard
Precautionary Statements: Avoid breathing dust. Wear protective gloves and eye protection. Do not eat, drink, or smoke when using this material. Wash hands thoroughly after handling. If in eyes, rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.
Chemical Name: N,N'-Methylenebisacrylamide
CAS Number: 110-26-9
Percentage: >99% pure
Impurities: Trace residual solvents or unreacted monomers (minimal, generally <0.1%)
Molecular Formula: C7H10N2O2
Molecular Weight: 154.17 g/mol
Inhalation: Move the affected individual to fresh air. Keep comfortable for breathing. Get medical advice if symptoms develop or persist. Seek immediate medical attention if shortness of breath occurs.
Skin Contact: Wash skin with plenty of soap and running water. Remove contaminated clothing and shoes. If irritation or rash develops, consult a physician.
Eye Contact: Rinse eyes with large amounts of water for at least 15 minutes. Hold eyelids open and move eyes in all directions during rinse. Get medical attention promptly.
Ingestion: Rinse mouth with water. Do not induce vomiting unless directed by medical personnel. Get immediate medical assistance. Never give anything by mouth to an unconscious person.
Most Important Symptoms: Burning sensation, rash, irritation, sensitization, allergic reactions
Suitable Extinguishing Media: Water spray, foam, dry chemical powder, carbon dioxide
Unsuitable Extinguishing Media: None known for this compound
Specific Hazards: Dust may form explosive mixture in air. Toxic fumes of nitrogen oxides, carbon oxides can form under fire conditions.
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and full protective gear to avoid inhalation of vapors or/decomposition products.
Advice for Firefighters: Cool containing vessels with water spray; try to prevent runoff from entering waterways.
Personal Precautions: Avoid breathing dust. Use adequate face protection, gloves, and chemical-resistant clothing. Ensure adequate ventilation.
Environmental Precautions: Avoid uncontrolled release into natural water sources, soil, or drains.
Containment and Clean Up: Sweep up using non-sparking tools and place in a suitable container for disposal. Avoid dust formation. Use wet methods if practical. Ventilate area and wash the spill site after material pickup is complete.
Safe Handling: Minimize dust generation and accumulation. Avoid contact with skin, eyes, and clothing. Wash thoroughly after use.
Storage Conditions: Store in a tightly closed, labeled container. Keep away from incompatible materials (strong oxidizers, strong acids). Store in a cool, dry, well-ventilated place.
Incompatible Materials: Strong acids, strong bases, oxidizing agents
Specific End Uses: Used in laboratory applications, particularly for gel preparation in research
Occupational Exposure Limits: No specific limits established; minimize exposure as a precaution.
Engineering Controls: Use local exhaust ventilation, safety eyewash stations, and handwashing facilities.
Personal Protective Equipment: Chemical safety goggles, suitable gloves (nitrile recommended), lab coat or coveralls, and respirator if dust is generated.
Hygiene Measures: Handle using good laboratory and industrial hygiene practices. Remove contaminated clothing and launder before reuse.
Appearance: White crystalline powder
Odor: Weak, characteristic
Odor Threshold: Not established
pH: Approx. 6-8 (1% aqueous solution)
Melting Point: 300°C (decomposes)
Boiling Point: Not applicable (decomposes)
Flash Point: Not applicable
Flammability: Not flammable under normal conditions
Vapor Pressure: Negligible
Solubility: Soluble in water, dimethyl sulfoxide, formamide
Density: Approx. 0.94 g/cm³
Partition Coefficient (log Pow): Not available
Decomposition Temperature: Above 300°C
Viscosity: Not applicable
Chemical Stability: Stable under recommended conditions of storage and use.
Possibility of Hazardous Reactions: Polymerization can occur with high temperatures or in the presence of free radical initiators.
Conditions to Avoid: Excessive heat, direct sunlight, ignition sources, incompatible materials
Incompatible Materials: Strong oxidizing agents, strong acids, and bases
Hazardous Decomposition Products: Nitrogen oxides, carbon dioxide, carbon monoxide, and potentially toxic organic compounds under fire or extreme heat
Acute Toxicity: Harmful if swallowed (LD50 oral rat ~390 mg/kg)
Skin Corrosion/Irritation: Can irritate on prolonged exposure
Serious Eye Damage/Irritation: Causes irritation
Respiratory or Skin Sensitization: May provoke allergic reactions from repeated or prolonged skin contact
Mutagenicity: Some studies suggest genotoxic effects in laboratory animals
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, or OSHA, but related acrylamide compounds have demonstrated potential carcinogenicity
Other Relevant Effects: Long-term exposure to fine dust may aggravate respiratory conditions. Repeated skin contact can result in sensitization or dermatitis.
Ecotoxicity: Limited data; not expected to be highly toxic to aquatic organisms, but can cause oxygen depletion or eutrophication issues in high concentrations.
Persistence and Degradability: Not readily biodegradable; degradation occurs slowly by environmental microorganisms
Bioaccumulative Potential: Expected to have low bioaccumulation in aquatic organisms
Mobility in Soil: Moderately mobile; may leach into groundwater under certain conditions
Other Adverse Effects: Avoid release in significant quantities. Megadose spills can impact aquatic habitats due to physical or chemical interactions with water bodies.
Disposal Methods: Collect spillage and transfer to a suitable container for proper incineration. Dispose of in accordance with all applicable local, regional, and national laws.
Contaminated Packaging: Rinse thoroughly; dispose of as chemical waste following hazardous waste procedures.
Special Precautions: Prevent material from entering uncontaminated environment, sewers, or water sources.
UN Number: Not classified for transport under UN model regulations
UN Proper Shipping Name: Not regulated as a hazardous material
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Marine Pollutant: Not defined as marine pollutant
Special Precautions for User: Avoid creating dust clouds, keep container tightly sealed during transport, and comply with local transport regulations.
Regulation Status: Not specifically regulated under major chemical safety frameworks such as TSCA, REACH, or DSL, but local reporting and safe use standards apply.
Labeling Requirements: Label containers with product name, hazard pictograms, signal word, and precautionary statements according to OSHA or EU CLP standards as applicable.
Exposure Reporting: Maintain proper records for workplace exposures in case of audits by regulatory authorities.
Safety Assessments: Regular workplace risk assessments and training recommended by occupational health guidance.
Chemical Inventories: Listed on major chemical inventories (TSCA, EINECS/ELINCS, etc.)
Restrictions: Intended for use in research and industry only; not designated for food, drug, or cosmetic purposes.
