© 2026 Nanjing Finechem Holdings Co., Ltd,
All Right Reserved
Name: Low Viscosity Hyaluronic Acid
Common Uses: Skin care formulations, injectables, wound care products
Physical Form: Fine white to off-white powder or clear, viscous solution if hydrated
Identifying Traits: Dissolves readily in water, forms a clear and smooth gel, has no noticeable odor
Main Hazards: In the dry powdered state, potential for mild eye and respiratory irritation during handling
Sensitization: Rare cases of mild allergic response upon direct prolonged skin contact
Health Effect: Not classified as a hazardous substance under GHS guidelines based on available evidence
Environmental Impact: Biodegradable and generally low in ecological toxicity, but accidental spillage into water systems could increase suspension load
Main Ingredient: Sodium hyaluronate (hyaluronic acid in sodium salt form), typically above 95% purity
Impurities: Trace amounts of acetic acid, protein residues from microbial fermentation, moisture below 10%
Potential Additives: Sometimes a stabilizer for shelf-life extension but usually pure in cosmetic and pharmaceutical grades
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, seek medical advice if discomfort persists
Skin Contact: Wash area with mild soap and water, remove contaminated clothing, apply skin lotion if irritation appears
Inhalation: Move to fresh air and rest comfortably, seek medical help if respiratory symptoms appear
Ingestion: Rinse mouth, drink water if conscious, no need for induced vomiting, consult health professional for large ingestion, though low toxicity is typical
Suitable Extinguishing Media: Water spray, foam, dry chemical, or carbon dioxide, due to low combustibility but potential for dust in dry conditions
Special Hazards: In case of fire, decomposition can yield carbon oxides and nitrogen oxides
Protective Equipment: Firefighters use self-contained breathing apparatus and suitable protective gear
Personal Precautions: Avoid creating airborne dust, ventilate area, wear basic protective equipment — gloves, mask, goggles
Environmental Precautions: Prevent discharge into drains and surface water
Clean-Up Methods: Sweep up dry powder carefully, keep in closed containers, clean with ample water to avoid slippery surfaces
Handling: Work with local exhaust or general ventilation, use personal protective equipment to limit skin and eye contact
Hygiene: Wash hands thoroughly after handling, avoid eating, drinking, or smoking in work areas
Storage: Store in tightly closed container away from light, heat, and moisture, refrigerate for long-term storage if possible
Ventilation: Use local exhaust in case of powder handling, avoid large-scale generation of dust
Eye Protection: Chemical safety goggles recommended
Skin Protection: Gloves suggested for prolonged contact, general laboratory coat advisable
Respiratory Protection: Dust mask recommended for weighing and transfer in open conditions
Appearance: Fine powder or clear, viscous gel when hydrated
Odor: Odorless
pH (1% Solution): Approximately neutral, typically between 6.0 and 7.5
Solubility: Soluble in water, insoluble in most organic solvents
Melting Point: Decomposes before melting
Viscosity: Low, characterized by easily pourable gels
Boiling Point: Not applicable due to decomposition
Chemical Stability: Stable under recommended storage conditions, sensitive to excessive heat and acidic/basic environments
Incompatible Materials: Strong oxidizing agents, concentrated acids and bases
Hazardous Decomposition: Degradation produces small amounts of ammonia, carbon oxides, nitrogen oxides at high temperatures
Acute Toxicity: Low toxicity through oral, dermal, and inhalation routes in animal studies
Chronic Effects: No evidence for carcinogenicity, teratogenicity, or reproductive toxicity in properly purified products
Allergic Reactions: Rarely reported, most often from protein contaminants
Potential Symptoms: Mild, short-term irritation in sensitive individuals
Persistence and Degradability: Rapidly biodegradable by microorganisms
Bioaccumulation: Not considered likely to bioaccumulate
Aquatic Toxicity: No significant toxicity observed in aquatic models at typical concentrations encountered in accidental release
Product Disposal: Small amounts can go in regular waste after mixing with water, larger quantities should be incinerated or processed according to local rules
Container Disposal: Rinse thoroughly and recycle or dispose of as non-hazardous waste if uncontaminated
Avoid Release: Prevent product residue from entering drains or surface water as a routine practice
UN Classification: Not classified as dangerous goods
Packing: Store in leakproof containers to prevent contact with water during transport
Special Precautions: No further transport restrictions, but care should go into avoiding significant moisture ingress
Regulatory Status: Not subject to major restriction under current EU REACH, US TSCA, or similar listings for the pure, pharmaceutical-quality form
Labeling: No hazard symbol required, but recommended to provide workplace labeling for worker awareness
Worker Protection: Covered by occupational safety standards for dusts and non-toxic powders, including recommendation for protective gear in manufacturing environments
