© 2026 Nanjing Finechem Holdings Co., Ltd,
All Right Reserved
Name: Latanoprost
Common Uses: Prescription eye drops for lowering intraocular pressure in glaucoma and ocular hypertension
Physical State: Clear, colorless liquid in multi-dose dropper bottles
Synonyms: Xalatan (brand name); prostaglandin F2α analogue
Chemical Formula: C26H40O5
CAS Number: 130209-82-4
Eye Contact: Strong local effect by design, accidental contact might irritate surrounding skin or mucous membranes
Skin Absorption: Not intended for skin use; repeated exposure may lead to discoloration or mild irritation
Inhalation: Not a notable route of exposure given form and intended use
Ingestion: Oral toxicity low in small amounts, but accidental ingestion carries risk of gastrointestinal discomfort
Chronic Effects: Increased pigmentation of iris and periocular skin with long-term exposure
Regulatory Symbol: None mandated in most regions, but proper handling applies
Active Ingredient: Latanoprost 0.005%
Inactive Ingredients: Benzalkonium chloride (preservative), sodium chloride, sodium phosphate (buffer), purified water
Potential Sensitizers: Benzalkonium chloride can provoke allergic or toxic reactions in sensitive individuals
Eye Contact Outside Intended Use: Flush eyes with water for several minutes if accidental splashing occurs
Skin Exposure: Wash area with mild soap and rinse thoroughly
Inhalation: Unlikely; move affected person to fresh air if symptoms develop
Ingestion: Rinse mouth, drink water; seek medical advice for quantities greater than one dosage
Symptoms: Discomfort, mild redness, increased tearing, rare risk of hypersensitivity or local swelling
Flammability: Non-flammable in typical concentrations
Combustion Products: Carbon oxides and other small organic molecules
Suitable Extinguishing Media: Water spray, foam, carbon dioxide, dry powder
Personal Protective Equipment: Standard firefighting gear, no specialty requirements
Special Hazards: Closed containers may rupture when exposed to extreme heat
Personal Precautions: Minimize direct skin contact, ventilate the area
Containment: Wipe up small spills using absorbent materials, taking care to avoid contamination of skin and eyes
Environmental Precautions: Prevent entry into water systems or sewage due to possible effects on aquatic life
Cleaning: Dispose of clean-up materials according to local regulations, wash surfaces well
Handling Practices: Apply with care to prevent accidental drops or splashes, avoid mixing with other eye medications unless prescriber-directed
Storage Requirements: Store refrigerated before opening, room temperature (below 25°C) after opening
Incompatibilities: Avoid storing near strong oxidizers; keep in original packaging to protect from light
Safe Practice: Keep out of reach of children, close cap tightly after use
Engineering Controls: No special systems needed in a healthcare or home setting
Personal Protection: Gloves for healthcare providers managing repeated exposure, avoid unnecessary hand-eye contact
Respiratory Protection: Not needed
Hygiene Measures: Wash hands before and after administering drops, avoid touching dropper tip to any surface
Exposure Limits: None established for general public
Physical State: Liquid
Color: Clear and colorless
Odor: None
pH: 6.7 – 7.7
Boiling/Melting Point: Not relevant at end-user concentrations
Solubility: Miscible with water
Partition Coefficient: High lipid solubility enables corneal penetration
Vapor Pressure: Negligible
Chemical Stability: Stable with proper storage
Hazardous Reactions: Will not react dangerously with most substances in normal use
Decomposition: Can break down under prolonged exposure to heat or light
Materials to Avoid: Strong oxidizing agents
Polymerization: Does not occur
Acute Toxicity: Low systemic toxicity at therapeutic doses
Epidemiological Data: No link to serious systemic side effects at prescribed use; rare allergic responses possible
Eye Effects: Conjunctival hyperemia, mild discomfort, gradual change in iris color with long-term exposure
Skin Effects: Possible darkening of eyelid skin
Cancer Risk: No solid evidence linking to human cancer in clinical studies
Reproductive Effects: Limited data, animal studies suggest possible risks at high systemic exposures
Other Risks: Asthmatic individuals warned to monitor for rare respiratory side effects
Aquatic Toxicity: Potential hazard at concentrated spill; no observed impact from routine patient use
Degradability: Breaks down slowly in environment
Bioaccumulation: Unlikely due to rapid metabolism in the body
Impact on Wastewater: Small quantities from home use likely negligible, but medical facilities urged to avoid bulk discharge
Patient Use: Dispose of empty or unused drops with household waste following local guidelines
Healthcare Facility: Treat as pharmaceutical waste, avoid incineration with non-controlled substances
Avoid: Flushing unused product down the sink or toilet
Recycling: Empty high-density polyethylene bottle may be accepted in some municipal recycling streams
Regulatory Status: Not regulated as hazardous for air, ground, or sea transport
Packing Instructions: No special requirements besides leak-proof packaging
Labeling: Marked as prescription medication
Handling Precautions: Protect from temperature extremes, keep upright where possible
Status: Prescription-only active pharmaceutical ingredient in most countries
Occupational Exposure Guidelines: None published for general setting
Pharmaceutical Controls: Subject to regulations for storage, labeling, and disposal
Environmental Regulations: Guidance to minimize environmental entry applies to unused product
