© 2026 Nanjing Finechem Holdings Co., Ltd,
All Right Reserved
Name: L-Norleucine
Chemical Formula: C6H13NO2
Synonyms: 2-Aminohexanoic acid
Appearance: White crystalline powder
Odor: No noticeable odor
Recommended Use: Research, chemical synthesis, peptide building
Molecular Weight: 131.17 g/mol
Classification: Considered a low-hazard amino acid compound
Specific Hazards: May cause mild skin and eye irritation with direct contact
Signal Word: None designated due to its relatively benign profile
Pictograms: Not assigned; risk is much lower than with corrosive or toxic agents
Potential Effects: Dust may irritate mucous membranes and the upper respiratory tract if inhaled
Chronic Exposure: No evidence suggests cumulative buildup or severe chronic effects
Main Ingredient: L-Norleucine (100%)
CAS Number: 327-57-1
Eye Contact: Flush eyes with cool, flowing water for several minutes, gently holding eyelids open
Skin Contact: Wash exposed area with soap and water—watch for persistent redness or rash
Inhalation: Move to fresh air and rest comfortably; seek medical advice if symptoms of irritation persist
Ingestion: Rinse mouth with water, avoid inducing vomiting, and drink water; seek further evaluation if a large amount is swallowed
Advice to Physicians: Treat symptoms supportively; specific antidote is unnecessary
Suitable Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or foam
Combustibility: L-Norleucine isn’t highly flammable but may burn under intense heat
Hazards from Combustion: Thermal decomposition yields carbon oxides and nitrogen oxides
Protective Equipment: Firefighters should rely on self-contained breathing apparatus and protective gear
Fire Practices: Limit dust dispersion to contain potential hazards, ventilate area well
Personal Precautions: Minimize dust generation, and avoid breathing any powder clouds
Protective Equipment: Wear gloves, safety glasses, and a dust mask or respirator
Cleanup Methods: Sweep or vacuum gently into sealed, labeled containers; avoid raising dust clouds
Disposal: Follow local regulations for non-hazardous chemical waste
General Handling: Prevent dust build-up, keep workspaces tidy, and avoid contact with eyes and skin
Storage: Store in a tightly sealed container in a dry, cool, well-ventilated space
Incompatible Materials: Avoid acids, strong oxidizers, and sources of moisture
Mishandling Risks: Although cases are rare, accidental inhalation or skin contact can irritate, so awareness promotes safer research and application environments
Occupational Exposure Limits: None designated by OSHA, NIOSH, or ACGIH because toxicity remains low
Personal Protective Equipment: Gloves, lab coats, and goggles safeguard against direct exposure
Engineering Controls: Handle powders in fume hoods or use local exhaust to avoid airborne particles
Hygiene Measures: Wash hands after handling and before eating or drinking
Environmental Controls: Prevent dust discharge into the environment—use vacuum or capture methods when transferring powder
Appearance: White powder or crystals
Odor: Absent or barely detectable
Melting Point: Around 145°C (decomposition possible at elevated temperatures)
Solubility: Slightly soluble in water, nearly insoluble in most organic solvents
Boiling Point: Not applicable
pH: Slightly acidic in solution
Vapor Pressure, Density: Not volatile, density similar to other amino acids
Stability in Light and Air: Stable under normal laboratory conditions
Chemical Stability: Retains form and reactivity in closed containers at room temperature
Hazardous Reactions: None identified under recommended conditions
Incompatible Materials: Strong oxidizers, reducing agents, strong acids
Decomposition Products: Releases carbon oxides and nitrogen oxides at high temperatures
Acute Toxicity: Experimental evidence and regulatory consensus indicate virtually no acute risk to healthy adults in typical laboratory settings
Irritation: Eye and skin irritation possible with repeated or prolonged exposure
Sensitization: No reports of allergic response at typical use concentrations
Ingestion Risk: Low at small doses typically encountered in research, potentially bothersome at large amounts
Carcinogenicity/Mutagenicity: No data connects L-Norleucine with chronic health hazards
Environmental Impact: Readily biodegradable, not persistent in soil or water
Aquatic Toxicity: No notable risk to aquatic organisms at expected environmental concentrations
Bioaccumulation: Rapid breakdown means negligible risk
Precautionary Practices: Avoid bulk release of powders to water courses or drains—simple containment and responsible disposal remain sufficient
Preferred Disposal: Deliver waste powders and unmixed excess to certified chemical disposal facilities
Waste Management: L-Norleucine’s profile allows disposal as general laboratory waste in most localities, but eco-conscious users segregate amino acid residues
Precautions: Prevent accidental contact during transfer, seal containers carefully, and label for clarity
Classification: Not regulated as a hazardous material for land, air, or sea transport in most jurisdictions
Packing Requirements: Use leak-proof, clearly labeled containers
Special Precautions: Keep containers closed, shielded from strong light and humidity, and upright during shipment
Global Status: L-Norleucine carries low regulatory concern due to its low toxicity profile
Reporting Thresholds: Not listed as a reportable hazardous substance; no volume thresholds for reporting under US TSCA or EU REACH as of latest guidance
Worker Safety Laws: General chemical handling rules apply—lab safety, proper training, access to eye wash and showers
Labeling: Simple identification and hazard labels suffice for compliance within most chemical research frameworks
