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Product Name: L-Menthol
Chemical Name: Cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1R,2S,5R)-
Chemical Family: Monoterpenoid alcohol
Molecular Formula: C10H20O
Molecular Weight: 156.27 g/mol
Synonyms: Levomenthol, p-Menthan-3-ol
CAS Number: 2216-51-5
Recommended Use: Flavors, pharmaceuticals, oral care products, cooling agent
Supplier Information: Manufacturer or supplier details printed on product packaging
GHS Classification: Acute Toxicity (Oral) Category 5; Eye Irritation Category 2A; Skin Irritation Category 2; Hazardous to the Aquatic Environment (Chronic) Category 2.
Signal Word: Warning
Hazard Statements: May cause skin irritation. Causes serious eye irritation. May be harmful if swallowed in large quantities. Toxic to aquatic life with long lasting effects.
Pictograms: Exclamation mark, Environment
Precautionary Statements: Avoid contact with eyes and skin. Wash after handling. Prevent release to the environment. Wear suitable protective equipment.
Chemical: L-Menthol
Concentration: ≥ 99%
CAS Number: 2216-51-5
Impurities: Trace levels of related monoterpenoids below reporting thresholds
Additives: None
Inhalation: Move person to fresh air. Seek medical help if symptoms appear.
Skin Contact: Wash with soap and water. Remove contaminated clothing. Seek attention if irritation persists.
Eye Contact: Rinse eyes thoroughly with water; continue for several minutes. Remove contact lenses if present. Seek immediate medical attention.
Ingestion: Rinse mouth. Do not induce vomiting. Drink water if conscious. Seek medical assistance if unwell.
Most Important Symptoms: Redness, irritation, burning sensation on eyes and skin. Nausea or discomfort if ingested.
Suitable Extinguishing Media: Use water spray, foam, dry chemical, or carbon dioxide.
Specific Hazards: Releases irritating or toxic fumes under fire conditions. Combustible solid.
Special Protective Equipment: Firefighters require full protective gear and self-contained breathing apparatus.
Advice for Firefighters: Evacuate area. Avoid inhalation of vapor, fumes, or decomposition products.
Personal Precautions: Avoid skin and eye contact. Isolate area. Keep unprotected persons away.
Environmental Precautions: Prevent undiluted product from reaching soil, waterways or drains. Notify authorities if large spill enters environment.
Methods for Clean Up: Provide adequate ventilation. Collect spilled material mechanically. Absorb residue with inert material such as sand or vermiculite. Dispose of according to local regulations. Wash spill site after material pick-up.
Handling: Use protective gloves and eyewear to reduce exposure risk. Handle in a well-ventilated area. Avoid splashing or aerosol formation.
Storage: Store in tightly sealed containers in a dry, cool, well-ventilated place. Keep away from heat sources, sparks, ignition sources, and direct sunlight. Store away from incompatible substances such as strong oxidizers.
Occupational Exposure Limit: No established limit for L-Menthol. Keep exposure as low as possible.
Engineering Controls: Use adequate ventilation to keep airborne concentrations below recommended limits. Consider local exhaust if handling large quantities.
Personal Protective Equipment: Wear chemical-resistant gloves and protective clothing. Use splash-proof safety goggles. In poorly ventilated spaces, use an approved respirator.
Hygiene Measures: Wash hands before breaks and at end of work. Do not eat, drink, or smoke when handling the product.
Appearance: White crystalline solid
Odor: Strong minty characteristic aroma
Odor Threshold: Low detection level due to intense odor
pH: Not applicable
Melting Point: 41°C - 44°C (106°F - 111°F)
Boiling Point: 212°C (414°F)
Flash Point: 93°C (199°F)
Evaporation Rate: Not determined
Flammability: Not highly flammable, but combustible
Vapor Pressure: 5.3 Pa at 25°C
Relative Density: 0.890 g/cm³ at 25°C
Solubility: Slightly soluble in water, highly soluble in ethanol, ether, chloroform, and oils
Partition Coefficient (log Kow): 3.4
Auto-Ignition Temperature: 255°C (491°F)
Decomposition Temperature: Not specified
Viscosity: Not applicable for a solid
Chemical Stability: Stable under recommended storage and handling conditions.
Reactivity: Inert at room temperature in absence of strong agents.
Hazardous Reactions: Avoid contact with strong oxidizing agents, strong acids.
Decomposition Products: Carbon monoxide, carbon dioxide, irritating fumes or gases when heated to decomposition.
Conditions to Avoid: Heat, flames, ignition sources, moisture, exposure to strong acids or alkalis.
Acute Toxicity, Oral: LD50 (rat): ~3300 mg/kg, low toxicity
Acute Toxicity, Dermal: LD50 (rabbit): >5000 mg/kg
Skin Irritation: Causes irritation in animal and some human studies
Eye Irritation: Causes serious irritation. May cause watering, redness, pain.
Respiratory Effects: May cause irritation of the upper respiratory tract if inhaled as dust.
Sensitization: Rare cases of skin sensitization reported.
Chronic Exposure: No long-term effects noted at typical exposure levels.
Carcinogenicity, Mutagenicity, Reproductive Toxicity: No evidence found in available data.
Other Effects: High doses may cause digestive discomfort
Ecotoxicity: Harmful to aquatic life with long lasting effects. Fish and daphnia toxicity studies show LC50 concentrations between 10 - 100 mg/L.
Persistence and Degradability: Moderately biodegradable through natural processes
Bioaccumulation Potential: May accumulate in aquatic organisms. Log Kow suggests moderate potential.
Mobility in Soil: Low due to limited water solubility. Can partition into sediments and organic matter.
Other Adverse Effects: Not expected to contribute significantly to ozone depletion, global warming, or photochemical ozone creation.
Waste Treatment: Dispose in accordance with local, regional, national, and international laws. Avoid disposal in sewers or natural water bodies.
Containers: Rinse containers well. Remove all labeling before recycling or disposal.
Special Precautions: Prevent large volumes from entering surface waters or soil. Seek professional chemical waste disposal contractors for bulk quantities.
UN Number: Not regulated for transport as a hazardous material
UN Proper Shipping Name: Not classified as dangerous goods under transport regulations
Transport Hazard Class: Not applicable
Packing Group: Not assigned
Environmental Hazards: Marine pollutant in bulk quantities
Special Precautions for User: Avoid releases to environment. Protect packaging from physical damage and moisture during transport.
International Inventories: Listed on TSCA (US), EINECS (EU), DSL (Canada), ENCS (Japan), AICS (Australia), KECI (South Korea)
OSHA Status: Not classified as hazardous under OSHA regulations
EPA Status: Not regulated as a specific hazardous waste
European Union: Not classified as a hazardous substance under CLP Regulation (EC) No. 1272/2008, but subject to general chemical safety laws
Other Regulations: Food-grade menthol subject to purity and labeling requirements in US and EU food and drug regulations
