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Material Safety Data Sheet (MSDS): L-Lysine Monohydrochloride

Identification

Product Name: L-Lysine Monohydrochloride
Synonyms: L-2,6-diaminohexanoic acid monohydrochloride, Lysine hydrochloride
Chemical Formula: C6H14N2O2·HCl
Molecular Weight: 182.65 g/mol
CAS Number: 657-27-2
Manufacturer: Supplier details, address, emergency contact numbers, recommended use for animal feed, pharmaceuticals, food supplements.

Hazard Identification

Classification: Not classified as hazardous based on GHS standards
Main Risks: Dust may cause mild respiratory irritation, possible eye discomfort, potential slight skin irritation, ingestion of large quantities could lead to mild gastric upset
Symbols: No specific hazard pictograms required
Pictograms: None
Signal Word: None
Precautionary Statements: Avoid inhaling dust, minimize skin and eye contact, use personal protection in bulk handling scenarios, maintain ventilation during transfer and mixing

Composition / Information on Ingredients

Chemical Name: L-Lysine Monohydrochloride
Concentration (typical): ≥98.5%
Impurities: Trace amino acids, water, minor salts
Other Components: None considered hazardous, fully disclosed upon request

First Aid Measures

Inhalation: Move person to fresh air, rinse mouth with water, seek medical attention for ongoing symptoms
Skin Contact: Remove contaminated clothing, wash skin thoroughly with soap and plenty of water, consult health provider if irritation persists
Eye Contact: Rinse eyes with water for at least 15 minutes, remove contact lenses, seek medical advice for persistent irritation
Ingestion: Rinse mouth, drink water, do not induce vomiting, get medical attention if feeling unwell or large amounts swallowed
Most Important Symptoms: Mild respiratory-mucous irritation, possible stomach discomfort after ingestion, rarely rash

Fire-Fighting Measures

Suitable Extinguishing Media: Use foam, dry powder, carbon dioxide, or water spray for small fires
Unsuitable Media: High-pressure water jet can spread material
Hazards from Combustion: Thermal decomposition may release nitrogen oxides, hydrochloric acid fumes, carbon monoxide
Protective Equipment: Firefighters use self-contained breathing apparatus and protective clothing
Special Procedures: Cool fire-exposed containers, avoid inhaling smoke, contain firewater runoff

Accidental Release Measures

Personal Precautions: Wear mask, gloves, goggles in case of dusty release
Environmental Precautions: Prevent large releases into waterways, inform authorities if necessary
Containment Methods: Sweep up spills, minimize dust generation, shovel into labeled containers for disposal or reuse
Cleaning Procedures: Vacuum or wet-brush residues, wash site with water
Disposal: Follow regulatory requirements for non-hazardous organics, consult waste carrier for large volumes

Handling and Storage

Precautions for Safe Handling: Prevent dust formation, avoid breathing particles, use with local exhaust, avoid eating or drinking around handling area
Hygienic Practices: Wash hands thoroughly after use, maintain clean work area
Storage Conditions: Store in tightly sealed bags/containers, keep in cool, dry, well-ventilated location, protect from moisture and direct sunlight
Incompatibilities: Away from strong acids, bases, oxidizers
Packaging Materials: Use food-grade or pharmaceutical-grade packaging for product intended for sensitive applications

Exposure Controls and Personal Protection

Occupational Exposure Limits: None established by OSHA, ACGIH, or EU for L-Lysine Monohydrochloride
Engineering Controls: Apply local exhaust ventilation during handling, dedicated dust extraction preferred in bulk processing
Personal Protective Equipment: Safety glasses or goggles, dust masks or respirators in high-concentration settings, gloves and protective clothing if repeated skin contact expected
Environmental Controls: Prevent dust from settling on surfaces, use closed transfer where possible
Specific Hygiene Measures: Routine hand and face washing, change out of work clothing before leaving facility

Physical and Chemical Properties

Appearance: White crystalline powder
Odor: Odorless or faint, characteristic
Odor Threshold: Not applicable
pH: 5.0 – 6.0 (10% solution)
Melting Point: Decomposes above 260°C
Boiling Point: Not applicable (decomposes before boiling)
Solubility: Freely soluble in water, practically insoluble in ethanol
Vapor Pressure: Negligibly low
Density: 1.28 g/cm³ at 20°C
Other Characteristics: Stable under ambient conditions, may clump if exposed to moisture

Stability and Reactivity

Chemical Stability: Stable at room temperature in sealed containers
Reactivity: Nonreactive under normal use, reacts with strong oxidizers and acids
Conditions to Avoid: Excessive heat, humidity, open air exposure
Incompatible Materials: Strong acids, strong oxidizers, strong bases
Hazardous Decomposition Products: Ammonia, nitrogen oxides, hydrochloric acid vapors above 260°C
Polymerization: Not expected to occur

Toxicological Information

Acute Toxicity: LD50 (oral, rat) >10,000 mg/kg
Chronic Effects: No significant health effects demonstrated from workplace or dietary exposure
Irritation: Mild irritation to skin and eyes possible in sensitive individuals
Sensitization: Not recognized as a skin or respiratory sensitizer
Carcinogenicity: Not listed by IARC, NTP, OSHA
Mutagenicity: Not found mutagenic in established assays
Reproductive Toxicity: No evidence of harmful effects on fertility or prenatal development at occupational exposure levels
Potential Health Effects: Occupational exposure risk low, overexposure may induce mild, reversible symptoms

Ecological Information

Ecotoxicity: Minimal expected impact, biodegradable amino acid salt
Aquatic Toxicity: Low, readily assimilated by microorganisms
Persistence and Degradability: Rapidly degrades in natural environments
Bioaccumulation Potential: Negligible, not likely to persist in organisms
Mobility in Soil: Water-soluble, may leach but unlikely to threaten groundwater quality
Other Adverse Effects: No known ozone depletion or long-term ecological impact

Disposal Considerations

Suitable Disposal Methods: Dispose through municipal, agronomic or industrial waste streams for non-hazardous organic compounds
Do Not: Release in concentrated form to surface waters
Special Instructions: Dilute or blend with compatible feedstock if reusing in agricultural setting
Packaging Disposal: Rinse and recycle bags, burn or landfill as allowed by local law
Regulatory Compliance: Check local, state, federal regulation for additional requirements relating to organic feed or pharmaceutical grade materials

Transport Information

UN Number: Not regulated for transport
Proper Shipping Name: L-Lysine Monohydrochloride
Transport Hazard Class: Not classified as dangerous goods
Packing Group: None assigned
Marine Pollutant: No
Special Precautions during Transport: Protect containers from water, puncture and excessive stacking
Label Requirements: No hazard labels needed for domestic or international road, sea, air freight
Other Transport Instructions: Ensure containers securely closed and properly labeled, document batch and shipping details for traceability

Regulatory Information

Global Inventory Status: Registered on TSCA, EINECS, REACH, DSL, AICS, and other major chemical inventories
US Regulation: Not classified as hazardous under OSHA, not subject to SARA Title III reporting, exempt from CERCLA
EU Regulation: No classification for health hazard under CLP, not considered persistent, bioaccumulative, or toxic
Other Regulation: Not on the list of controlled substances for food additive use, permitted for use in animal nutrition and food applications in accordance with Codex and local standards
Label Requirements: Ingredient disclosure, lot number, recommended storage and safe handling advice
Worker Right-to-Know: Safety datasheet available and accessible for all staff in handling areas