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Product Name: L-Isoleucine
Synonyms: 2-Amino-3-methylpentanoic acid
CAS Number: 73-32-5
Molecular Formula: C6H13NO2
Molecular Weight: 131.17 g/mol
Recommended Use: Amino acid supplement, laboratory reagent, pharmaceutical ingredient
Supplier Information: Supplier and contact information should appear on packaging or in purchase order
Emergency Contact: Local poison control center or supplier emergency response number
GHS Classification: Not classified as hazardous according to OSHA Hazard Communication Standard (29 CFR 1910.1200)
Potential Health Effects: Eyes: Possible irritation. Skin: May cause slight irritation with prolonged contact. Inhalation: Dust may cause mild respiratory irritation. Ingestion: Low toxicity, large amounts may cause upset stomach.
Label Elements: None required under GHS
Signal Word: No signal word
Hazard Pictograms: None
Precautionary Statements: Avoid breathing dust, wash hands after handling, use common sense hygiene
Chemical Name: L-Isoleucine
Concentration: >98%
Impurities or Stabilizing Additives: No significant impurities relevant for classification
Ingredient Type: Single substance
CAS Number: 73-32-5
Eye Contact: Rinse immediately under running water for at least 15 minutes. Remove contact lenses if possible.
Skin Contact: Remove contaminated clothing. Wash skin thoroughly with soap and water.
Inhalation: Move person to fresh air. Seek medical assistance if respiratory symptoms continue.
Ingestion: Rinse mouth with water. Drink plenty of water to dilute. Consult a physician if large amounts are swallowed or symptoms persist.
Most Important Symptoms: Mild irritation, discomfort
Medical Attention Needed: Seek attention if symptoms do not resolve or large amounts consumed
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Unsuitable Extinguishing Media: Strong water stream may spread burning powder
Specific Hazards from Fire: Fine dust may form combustible dust clouds. Burning may produce carbon oxides, nitrogen oxides.
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective clothing.
Special Procedures: Avoid raising dust, evacuate non-essential personnel, use protective barriers if risk of explosion
Hazardous Combustion Products: Carbon dioxide, carbon monoxide, nitrogen oxides
Personal Precautions: Avoid dust formation, avoid inhaling dust, ventilate area
Protective Equipment: Use dust-proof goggles, appropriate gloves, dust mask if needed
Emergency Procedures: Evacuate area if large spill, isolate hazard area
Methods for Containment: Sweep up and place in suitable container, avoid creating clouds
Methods for Cleanup: Vacuum up or carefully shovel, rinse area with water after material removed
Environmental Precautions: Prevent entry to waterways and sewers, report large spills to local authorities
Disposal: Dispose of collected waste according to local regulations
Handling: Minimize dust generation and accumulation, maintain good industrial hygiene, wash hands often, avoid contact with eyes or skin
Personal Protection: See Exposure Controls and Personal Protection section
Safe Storage: Store in cool, dry, well-ventilated area away from incompatible substances, keep container tightly closed
Incompatibilities: Strong oxidizing agents, acids, alkalis
Other Storage Requirements: Prevent moisture entry, keep away from food and drink
Occupational Exposure Limits: No established limits for L-Isoleucine
Engineering Controls: Use local exhaust or general ventilation to keep airborne concentrations below recommended limits
Respiratory Protection: Dust mask recommended for routine handling of powders
Eye Protection: Safety goggles or glasses
Skin Protection: Wear suitable protective gloves and clothing
Hygiene Measures: Wash hands after handling, remove contaminated clothing, avoid eating or drinking in handling areas
Appearance: White crystalline powder
Odor: Odorless
Odor Threshold: Not applicable
pH: 5.5–7.0 (1% solution in water)
Melting Point: Around 284°C (decomposes)
Boiling Point: Not available (decomposes before boiling)
Flash Point: Not applicable
Evaporation Rate: Not relevant for solids
Flammability (Solid, Gas): May form combustible dust clouds
Vapor Pressure: Not applicable
Vapor Density: Not applicable
Solubility: Slightly soluble in cold water
Partition Coefficient (n-octanol/water): -1.52
Auto-Ignition Temperature: Not determined
Decomposition Temperature: >200°C
Viscosity: Not applicable
Chemical Stability: Stable under normal conditions
Reactivity: Will not react readily at ambient temperatures
Conditions to Avoid: High humidity, sources of ignition, excessive heat
Incompatible Materials: Strong oxidizers, acids, bases
Hazardous Decomposition Products: Carbon dioxide, carbon monoxide, nitrogen oxides
Hazardous Polymerization: Will not occur
Acute Toxicity: Oral LD50 (rat): >5,000 mg/kg, practically non-toxic
Skin Corrosion/Irritation: No sensitizing or irritant effects observed
Eye Damage/Irritation: May cause mild irritation
Respiratory Sensitization: No data available
Germ Cell Mutagenicity: Not classified as mutagenic
Carcinogenicity: Not listed by IARC, NTP, or OSHA
Reproductive Toxicity: No evidence of toxicity to reproduction
STOT (Specific Target Organ Toxicity): Not classified
Aspiration Hazard: Not an aspiration hazard
Chronic Effects: No known long-term health effects in typical handling scenarios
Toxicity to Aquatic Life: Not expected to be harmful to aquatic organisms
Persistence and Degradability: Readily biodegradable in the environment
Bioaccumulative Potential: Low potential due to water solubility and rapid metabolism
Mobility in Soil: High mobility, does not adsorb strongly to soil particles
Other Adverse Effects: None expected under normal use and disposal
Waste Disposal Methods: Dispose in accordance with local, state, and federal regulations
Contaminated Packaging: Dispose as unused product
Special Precautions: Prevent uncontrolled release to environment, avoid creating dust
Recommended Treatment: Landfill or incinerate following local environmental regulations
UN Number: Not regulated
UN Proper Shipping Name: Not regulated
Transport Hazard Class: Not regulated
Packing Group: Not regulated
Marine Pollutant: No
Special Transport Precautions: Avoid heavy vibration, seal container tightly, keep away from incompatible materials during transit
TSCA: Listed on the US Toxic Substances Control Act Inventory
DSL/NDSL (Canada): Listed
EINECS/ELINCS (EU): 200-798-2
REACH Registration: Exempt or registered as a low-hazard substance
OSHA: Not classified as hazardous
SARA Title III: Not subject to reporting
California Proposition 65: Not listed
Other National Regulations: Compliant with European, Japanese, and Australian chemical inventories
Labeling Requirements: None required for non-hazardous classification by GHS
Other Regulatory Details: Intended for use in accordance with FDA, USP, or food code standards if used in food or dietary supplement settings
