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Chemical Name: Isopropyl Palmitate
Synonyms: Propan-2-yl hexadecanoate
CAS Number: 142-91-6
Physical Form: Typically appears as a clear, almost colorless liquid
Common Uses: Regularly used as a skin-conditioning agent in cosmetics, personal care items, and some pharmaceutical preparations
Hazard Classification: Generally considered low hazard for routine handling
Signal Word: None required for most environments
Potential Health Effects: May cause mild irritation to skin and eyes for sensitive individuals; ingestion in large quantities could upset the stomach
Environmental Risk: Known to have limited aquatic toxicity, but large spills may have consequences for small aquatic organisms
Fire Hazard: Classified as combustible, not highly flammable, but vapors can catch fire with strong ignition sources
Main Ingredient: Isopropyl Palmitate, purity usually above 96%
Minor Impurities: Trace levels of related fatty acid esters
No Added Solvents: Pure form contains no significant additives or stabilizers in most commercial uses
Eye Exposure: Rinse gently with clean water, remove contact lenses if present, consult a physician if irritation lingers
Skin Contact: Wash with mild soap and water, monitor for persistent redness or rash
Inhalation: Move to fresh air, support breathing if exposed to heavy vapors from heating
Ingestion: Rinse mouth, do not force vomiting, drinking water can help dilute the substance, get medical advice for any discomfort
Sensitivity to Ignition: Product will burn in a fire but does not easily ignite
Suitable Extinguishing Media: Foam, dry chemical powder, or carbon dioxide recommended
Protective Gear: Firefighters should use standard protective clothing and self-contained breathing apparatus
Hazardous Combustion Products: Burning may produce carbon monoxide and carbon dioxide
Special Fire Procedures: Avoid inhaling smoke, isolate area if possible
Personal Precautions: Avoid direct contact with skin and eyes, wear gloves
Environmental Precautions: Prevent spills from entering drains or waterways
Containment: Absorb liquid with sand, earth, or vermiculite
Cleanup: Use non-sparking tools to collect residues, dispose through approved waste handlers
Handling: Use in ventilated spaces, avoid breathing in vapors from heated product
Spill Response: Clean minor spills quickly; for large spills, evacuate unnecessary personnel until area is ventilated
Storage Conditions: Store in tightly closed containers, keep away from heat and open flames
Compatibility: Keep away from strong oxidizing agents, which could react with the ester bond
Long-Term Stability: Shelf life is typically reliable if unopened and stored in cool, dry place
Engineering Controls: Local exhaust recommended for large-volume operations
Personal Protection: Chemical-resistant gloves, safety goggles, lab coat or apron
Inhalation Protections: Respiratory protection required only if mists or vapors are present in significant quantities
Hygiene Practices: Wash hands thoroughly after handling, do not eat or drink while using the chemical
Appearance: Clear, colorless or very pale-yellow liquid
Odor: Faint, characteristic
Boiling Point: Near 337°C
Melting Point: Approximates -4°C
Flash Point: Around 148°C
Density: Around 0.85 g/cm³ at 25°C
Solubility: Insoluble in water, freely mixes with organic solvents and oils
Viscosity: Feels oily or slippery
Partition Coefficient (log Kow): High, signaling preference for fats over water
Chemical Stability: Stable under normal temperatures and pressures
Hazardous Reactions: Unlikely as long as kept away from strong oxidizers
Decomposition: Degrades with strong acids or bases resulting in palmitic acid and isopropanol
Polymerization: Not known to occur
Routes of Exposure: Main risks are through skin or eye contact
Acute Toxicity: Low, with little evidence of harm under normal use
Chronic Effects: Not known to build up in the body or cause long-term toxicity
Allergy Potential: Rare but possible contact dermatitis for some individuals
Inhalation Risk: Only an issue if heated to vapors; not a risk in room temperature use
Persistence: Slow to break down in the environment, like most long-chain fatty esters
Bioaccumulation: Shows some tendency to remain in aquatic systems, mainly because of low solubility in water
Aquatic Toxicity: Low, but can cause issues if dumped in large quantities
Degradation: Breaks down to fatty acid and isopropanol through environmental processes
Preferred Disposal: Send to an approved chemical waste facility or incinerator
Do Not Drain: Product should not be poured down the sink or regular sewer lines
Container Management: Empty packaging should be triple-rinsed and disposed according to local guidelines
Regulatory Status: Not regulated as a dangerous good for most routes of transportation
Handling in Transit: Basic controls for liquids apply; containers need to be tightly sealed to prevent leaks
Labeling: Standard labeling for non-hazardous chemical products; still requires chemical identification
Country-Specific Listings: Recognized as a cosmetic ingredient in major regulatory bodies such as FDA and EU’s Cosmetic Regulation
Workplace Regulations: Not listed as a hazardous substance; no specific occupational exposure limits set by OSHA or similar agencies
Consumer Products: Approved for leave-on and rinse-off applications in skin care by many global health agencies
Monitoring: Regular reviews ensure compliance with current health and safety laws; changes in classification arise from new toxicology research
