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Ionomycin Calcium Salt - Material Safety Data Sheet (MSDS)

Identification

Product Name: Ionomycin Calcium Salt
Chemical Formula: C41H70CaO9
CAS Number: 56092-81-0
Recommended Use: Research, laboratory reagent, calcium ionophore applications
Supplier: Chemical supply companies specializing in laboratory reagents
Contact Details: Supplier customer service or safety lines; refer to product label for emergency numbers
Synonyms: Calcium salt of ionomycin, Ionomycin, calcium complex

Hazard Identification

Classification: Eye irritant, Skin irritant, Harmful if inhaled or swallowed, Target organ effects not fully studied in humans
GHS Label Elements: Exclamation mark symbol for harm
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation, may cause respiratory irritation, harmful if swallowed, acute toxicity not fully evaluated on chronic exposure
Precautionary Statements: Avoid breathing dust or vapors, avoid contact with skin and eyes, wash hands thoroughly after handling, use only outdoors or in well-ventilated areas

Composition / Information on Ingredients

Chemical Name: Ionomycin calcium salt
Concentration: ≥98% purity (for research grade)
Impurities: Trace organic and inorganic contaminants possible from synthesis, not expected to be significant
Other Ingredients: None known, single active substance

First Aid Measures

Inhalation: Move to fresh air as quickly as possible. If symptoms like coughing or difficulty breathing develop, seek medical attention
Skin Contact: Wash off immediately with soap and plenty of water. Remove contaminated clothing. If irritation develops or persists, consult a healthcare provider
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do; keep rinsing. Get medical help if discomfort continues
Ingestion: Rinse mouth with water, do not induce vomiting. If the person feels unwell, get instant medical advice
Critical Acute Symptoms: Seek medical care if respiratory symptoms, severe skin/eye irritation occur after exposure

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical, foam, carbon dioxide
Unsuitable Media: Do not use strong water jets because splashing may occur
Specific Hazards: Product can burn, releasing toxic fumes such as carbon oxides and calcium oxides
Protective Equipment for Firefighters: Wear self-contained breathing apparatus, flame-resistant clothing, and gloves
Special Procedures: Cool containers exposed to fire with water spray; move away from area if safe to do so

Accidental Release Measures

Personal Precautions: Avoid formation of dust, use protective gloves, safety goggles, lab coats, and masks
Environmental Precautions: Prevent product from entering drains, surface water, and soil
Cleanup Methods: Collect spill using a method that minimizes dust formation (damp cloth or HEPA vacuum), place in a suitable container for disposal, ventilate area
Decontamination: Clean affected surfaces thoroughly with soap and water after removal of material
Emergency Procedures: Evacuate unnecessary people from the spill area; notify specialists if significant quantity released

Handling and Storage

Safe Handling Advice: Work in a chemical fume hood or well-ventilated area, wear personal protective equipment, avoid direct contact, open containers carefully
Hygiene Measures: Wash hands after handling, remove contaminated clothing before breaks, avoid eating/drinking/smoking near the substance
Storage Conditions: Store tightly closed, away from incompatible substances, in a cool, dry, ventilated area. Typical storage temperatures range from 2–8°C (refrigerator), protect from light
Incompatible Materials: Strong acids, strong oxidizers; risk of reaction exists
Storage Container Materials: Use original containers or chemically resistant bottles, labeled clearly with hazard and content information

Exposure Controls and Personal Protection

Exposure Limits: No established occupational exposure limit; minimize exposure as a precaution
Engineering Controls: Laboratory fume hood, local exhaust ventilation
Personal Protective Equipment: Lab coat, gloves (nitrile or latex), chemical splash goggles, respiratory protection if risk of dust or aerosol formation
Work Practices: Avoid dust generation and inhalation, keep work area clean, label all containers and wastes
Monitoring Procedures: Regular checks for airborne concentration (if used in bulk); area monitoring for spills or leaks after use

Physical and Chemical Properties

Appearance: Off-white to pale yellow powder or solid
Odor: No significant odor under normal lab handling
pH: Not available (not water soluble)
Melting Point/Freezing Point: Approximately 184°C (decomposes)
Boiling Point: Not established, decomposition occurs before boiling
Solubility: Soluble in DMSO, ethanol, methanol; slightly soluble in water
Vapor Pressure: Not applicable (low volatility solid)
Relative Density: Not quantified (likely 1.2–1.4 g/cm³)
Partition Coefficient (n-octanol/water): Not available
Flash Point: Not available
Evaporation Rate: Not applicable due to low volatility
Auto-ignition Temperature: Not available
Upper/Lower Flammability Limits: Not determined

Stability and Reactivity

Chemical Stability: Stable under recommended storage, protected from moisture and light
Conditions to Avoid: Exposure to air, moisture, high temperatures, light, incompatible chemicals
Hazardous Reactions: May react with strong acids or oxidizers, risk of decomposition under untested conditions
Hazardous Decomposition Products: Toxic fumes of carbon oxides, calcium oxides when exposed to excessive heat or flames
Polymerization: No risk of hazardous polymerization recognized

Toxicological Information

Acute Toxicity: Oral and dermal toxicity not fully established; laboratory evidence suggests risk if ingested or absorbed through skin
Skin Corrosion/Irritation: Skin irritation possible, especially after prolonged or repeated contact
Eye Damage/Irritation: Expected to irritate, contact results in discomfort or injury
Inhalation: Inhalation can cause respiratory tract irritation, coughing, difficulty breathing
Chronic Effects: Repeated exposure not thoroughly evaluated in animal or human studies
Carcinogenicity: Not designated as carcinogen by IARC, ACGIH, NTP, OSHA
Mutagenicity/Teratogenicity: Not sufficiently studied
Sensitization: Not classified as a respiratory or skin sensitizer

Ecological Information

Ecotoxicity: Little direct study, but calcium ionophores can disrupt cellular signaling pathways in aquatic organisms at low concentrations
Persistence and Degradability: Product likely to degrade slowly; chemical structure indicates some persistence in the environment
Bioaccumulative Potential: No data, bioaccumulation unlikely for most ionophores
Mobility in Soil: Limited due to low water solubility, expected to adhere to particulate matter
Other Adverse Effects: Careless discharge can disrupt microbial or aquatic activity; best to avoid release

Disposal Considerations

Waste Treatment Methods: Collect substance and contaminated items in a tightly sealed, labeled chemical waste container, handle as hazardous waste
Disposal Procedures: Dispose through certified hazardous material incinerator or licensed chemical waste contractor, do not pour down drains or mix with general trash
Container Disposal: Rinse and triple-clean empty containers, remove labels, follow institution or local hazardous waste procedure
Environmental Precaution: Prevent spills and avoid release into soil or water since environmental risks exist

Transport Information

UN Number: Not regulated for small laboratory quantities
UN Proper Shipping Name: Not assigned, treat as chemical sample
Transport Hazard Class: Not classified under most regulations
Packing Group: Not assigned
Special Precautions: Ensure leak-proof packaging, label as laboratory chemical, carry safety data for reference during transport
Transport in Bulk: Not recommended
DOT/IATA/IMDG regulations: Follow institutional policies for chemical shipment

Regulatory Information

TSCA Status: Not listed for commercial manufacturing in the USA, research exemption applies
REACH Status: Registered for research uses in the EU, requires notification for commercial supply
OSHA SDS Requirement: Provided for workplace safety according to 29 CFR 1910.1200
Other Global Listings: Research-use only chemical; not registered for food, drug, or cosmetic application; not subject to SARA Title III reporting
Product Labeling: Clear hazard and precaution labels required with GHS pictograms
Other Requirements: Training and access to SDS necessary for users, local and national laws may require reporting for larger spills or accidents