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Product Name: Iodomethane
Synonyms: Methyl iodide
Chemical Formula: CH3I
CAS Number: 74-88-4
Recommended Use: Laboratory reagent, methylating agent in organic synthesis, fumigant
Supplier Details: Contact information for chemical manufacturer or distributor
Emergency Contact: Designated emergency telephone number for incidents involving spills, exposure, or fires
Classification: Acute toxicity (oral, dermal, inhalation); Skin irritation; Eye irritation; Carcinogenicity; Reproductive toxicity
GHS Label Elements: Skull and crossbones, exclamation mark, health hazard
Signal Word: Danger
Hazard Statements: Harmful if swallowed, toxic in contact with skin or if inhaled, causes skin and eye irritation, suspected of causing cancer, may damage fertility or the unborn child, may cause respiratory irritation
Precautionary Statements: Avoid breathing vapors, wash thoroughly after handling, use only outdoors or in a well-ventilated area, wear protective gloves, clothing, eye and face protection, do not eat, drink or smoke during use
Substance: Iodomethane
Concentration: 100%
Chemical Name: Iodomethane
CAS Number: 74-88-4
Impurities and Stabilizing Additives: None reported in pure product
Inhalation: Remove affected person to fresh air, keep at rest and warm, seek medical attention right away, administer oxygen if breathing is difficult
Skin Contact: Take off contaminated clothing, wash skin immediately with water and soap for at least 15 minutes, obtain medical attention
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, continue rinsing, seek prompt medical advice
Ingestion: Rinse mouth, do not induce vomiting, never give anything by mouth to an unconscious person, call poison control or doctor at once
Most Important Symptoms/Effects: Central nervous system depression, dizziness, nausea, headache, confusion, skin redness or blistering
Suitable Extinguishing Media: Use dry chemical, carbon dioxide, foam, or water spray
Unsuitable Media: Do not use water jet directly on chemical to avoid spreading
Hazards from Combustion: Produces toxic gases, including hydrogen iodide, carbon monoxide, carbon dioxide
Protective Equipment: Firefighters wear self-contained breathing apparatus, full protective gear
Special Procedures: Move containers from fire area if safe, cool equipment exposed to fire with water spray, prevent runoff from entering drains or waterways
Personal Precautions: Evacuate area, ventilate space, avoid breathing fumes, wear chemical-resistant gloves, goggles, and suitable respiratory protection
Environmental Precautions: Prevent release to environment, avoid contamination of drains, soil, and water
Methods for Clean Up: Absorb spill with inert material such as dry sand or earth, shovel into suitable container for disposal, wash spill site after material pickup is complete, ventilate affected area
Decontamination: Use appropriate cleansing agents, discard contaminated clothing in sealed containers for safe disposal
Safe Handling: Use only with adequate ventilation, avoid contact with skin, eyes, and clothing, do not inhale vapors, handle away from ignition sources or heat
Hygiene Measures: Wash hands after use, do not eat, drink, or smoke in working area
Storage Conditions: Keep tightly closed in original container, store in a cool, dry, well-ventilated area away from direct sunlight, separate from incompatible substances such as strong bases, oxidizers, aluminum, tin
Special Precautions: Use corrosion-resistant containers, label storage container clearly, avoid excess mechanical shock and rough handling
Exposure Limits: OSHA PEL: 2 ppm (10 mg/m3); ACGIH TLV: 2 ppm (8-hour TWA), 1 ppm STEL
Engineering Controls: Use local exhaust ventilation, fume hood, or other engineering means to keep airborne levels below limits
Personal Protective Equipment: Wear chemical-resistant gloves (butyl rubber, neoprene), chemical splash goggles, protective clothing including apron or coveralls, approved respirator if ventilation is inadequate
Other Precautions: Eye wash station and emergency shower in working area, regular medical monitoring for frequent users
Appearance: Colorless, volatile liquid
Odor: Penetrating, sweet
Odor Threshold: Not available
pH: Not applicable
Melting Point: -66 °C
Boiling Point: 42 °C
Flash Point: -9 °C (closed cup)
Evaporation Rate: High
Flammability: Flammable liquid
Vapor Pressure: 400 mmHg at 25 °C
Vapor Density: 4.3 (air = 1)
Relative Density: 2.28 (water = 1)
Solubility: Slightly soluble in water, miscible with ether, ethanol, benzene
Partition Coefficient (log Kow): 1.38
Auto-Ignition Temperature: 525 °C
Decomposition Temperature: Not available
Viscosity: Not available
Chemical Stability: Stable under recommended storage conditions
Reactivity: Reacts strongly with bases, strong oxidizing agents, metals such as aluminum, tin, and magnesium
Possibility of Hazardous Reactions: Polymerization not expected, hazardous decomposition possible if heated or mixed with incompatible substances
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, hydrogen iodide, methyl radicals
Conditions to Avoid: Heat, open flames, sparks, direct sunlight, moisture
Incompatible Materials: Strong alkalis, oxidizers, metals including aluminum, magnesium, tin
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Acute Toxicity: LD50 oral (rat): 76 mg/kg; LD50 dermal (rabbit): 200 mg/kg; LC50 inhalation (rat, 4h): 1300 ppm
Symptoms: Dizziness, headache, anesthetic effects, nausea, vomiting, skin and eye irritation, pulmonary edema, central nervous system depression
Chronic Effects: Possible carcinogen, reproductive effects, liver and kidney damage with long-term exposure
Sensitization: Not reported
Mutagenicity: Evidence of genetic damage in animal studies
Reproductive Toxicity: Animal studies indicate risk of harm to unborn child
Ecotoxicity: Highly toxic to aquatic organisms; LC50 (fish, 96 h): 4.8 mg/L
Persistence and Degradability: Moderately persistent, slow biodegradation in water and soil
Bioaccumulative Potential: Log Kow 1.38, low to moderate potential for bioaccumulation
Mobility in Soil: Relatively high, may leach to groundwater
Other Hazards: Ozone depletion potential, photodegrades to form toxic products in sunlight, possible groundwater contaminant where used as fumigant
Waste Disposal Methods: Dispose as hazardous waste, incinerate in licensed chemical incinerator with afterburner and scrubber, consult local environmental authorities
Contaminated Packaging: Rinse container thoroughly, dispose of as hazardous chemical waste, do not reuse containers
Disposal Precautions: Do not pour into drains, surface water, or soil; prevent leaks to environment
Special Considerations: Follow all local, state, and federal regulations on hazardous chemical disposal, keep records of disposal processes
UN Number: UN2644
Proper Shipping Name: Iodomethane
Transport Hazard Class: 3 (Flammable liquid), 6.1 (Toxic substance)
Packing Group: I (highest danger)
Environmental Hazards: Marine pollutant
Special Precautions: Shipped in approved containers, label and mark according to international regulations, transport emergency card required, only trained personnel should handle during transit
OSHA: Covered under Hazard Communication Standard, listed as hazardous
TSCA: Listed
SARA 313: Listed chemical (toxic chemical category)
California Proposition 65: Listed as carcinogen and reproductive toxin
EPA: Designated hazardous air pollutant, use strictly regulated, subject to reporting requirements
International Inventories: Registered in major chemical inventories including REACH (EU), DSL (Canada), AICS (Australia), ENCS (Japan)
Other Regulations: Subject to significant restrictions and bans in fumigation or pesticide uses in several countries, consult national chemical safety authority for site-specific rules
