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Product Name: Imidazole
Chemical Name: Imidazole
Synonyms: Glyoxaline, 1,3-Diazole
CAS Number: 288-32-4
Molecular Formula: C3H4N2
Molecular Weight: 68.08 g/mol
Recommended Use: Laboratory chemicals, research and development
Supplier Details: Manufacturer or distributor contact information available upon request
Emergency Contact: Call local emergency services or poison control
GHS Classification: Acute toxicity (oral, dermal), Skin irritation, Eye irritation, Respiratory sensitization
Pictograms: Exclamation mark
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation, may cause respiratory irritation, harmful if swallowed
Precautionary Statements: Avoid breathing dust, wash hands thoroughly after handling, wear protective gloves and eye protection, if in eyes rinse with water
Other Hazards: May cause allergic reactions in sensitive individuals, potential environmental impact if released in large quantities
Chemical Name: Imidazole
Concentration: >98% (pure substance)
CAS Number: 288-32-4
Impurities: Negligible, usually less than 2% depending on source
Additives: None for reagent grade, may contain trace stabilizers in some formulations
Eye Contact: Rinse cautiously with water for several minutes; remove contact lenses if present; seek medical advice if irritation occurs
Skin Contact: Wash with plenty of soap and water; remove contaminated clothing; seek medical attention for persistent irritation
Inhalation: Move person to fresh air; give artificial respiration if not breathing; seek medical attention if symptoms persist
Ingestion: Rinse mouth with water; do not induce vomiting; seek immediate medical help
Most Important Symptoms: Irritation, redness, nausea, coughing, difficulty in breathing
Advice to Doctors: Treat symptoms, support vital functions, observe for delayed effects
Suitable Extinguishing Media: Water spray, carbon dioxide, foam, dry chemical
Unsuitable Media: Avoid direct water stream on burning substance
Specific Hazards: Combustible solid, may form hazardous decomposition products such as nitrogen oxides, carbon oxides under fire
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective clothing
Special Procedures: Use water spray to cool containers; prevent water runoff from entering drains or waterways
Explosion Data: Does not form explosive mixtures under normal handling, but fine particulates can pose dust explosion hazard
Personal Precautions: Use personal protective equipment, avoid contact with skin and eyes, ensure adequate ventilation
Environmental Precautions: Prevent further leakage or spillage, do not let product enter drains
Containment Methods: Collect spilled material in suitable containers for disposal, cover powder spills with plastic sheet if necessary
Cleanup Procedures: Sweep or scoop up, avoid creating dust, wipe area with damp cloth, dispose according to regulations
Notification Requirements: Notify local authorities if large spills occur or if product enters public waters
Handling: Avoid dust formation, avoid contact with skin, eyes, and clothing; use only in well-ventilated areas, use appropriate personal protection
Storage Conditions: Store tightly closed in a cool, dry, well-ventilated place, keep away from incompatible materials such as strong oxidizers and acids
Storage Class: Chemical storage, away from foodstuffs and combustible materials
Other Precautions: Keep container tightly sealed, store out of reach of children, label all containers clearly
Occupational Exposure Limits: No specific national limits established, keep to general dust exposure guidelines (e.g. ACGIH TLV for particulates not otherwise regulated: 10 mg/m3)
Engineering Controls: Use fume hood, local exhaust, or adequate ventilation
Eye Protection: Safety goggles or face shield
Skin Protection: Protective gloves (nitrile, PVC recommended), laboratory coat
Respiratory Protection: Use dust mask or respirator if dust or aerosols are encountered
Hygiene Measures: Wash hands and forearms before breaks and after work, do not eat or drink around the substance
Environmental Exposure Controls: Do not allow material to contaminate soil or water
Appearance: White to light beige crystalline powder
Odor: Mild, ammonia-like
Odor Threshold: Not established
pH: 10.0–11.0 (for a 1% solution in water)
Melting Point/Freezing Point: 88–91°C
Boiling Point: 257°C
Flash Point: 145°C (closed cup)
Evaporation Rate: Not determined
Flammability: Not highly flammable but will burn
Upper/Lower Flammability Limits: Not available
Vapor Pressure: Very low at room temperature
Vapor Density: 2.3 (air=1)
Relative Density: 1.03–1.05 g/cm3 at 20°C
Solubility: Soluble in water, ethanol, methanol
Partition Coefficient (n-octanol/water): -0.02
Auto-Ignition Temperature: 590°C
Decomposition Temperature: Not determined
Viscosity: Not applicable (solid)
Chemical Stability: Stable under recommended storage conditions
Reactivity: May react with strong oxidizing agents, acids, acyl chlorides
Hazardous Reactions: No known hazardous polymerization
Conditions to Avoid: Moisture, heat, sources of ignition, incompatible chemical substances
Incompatible Materials: Strong oxidizing agents, strong acids, anhydrides
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide under thermal decomposition
Acute Toxicity: Oral LD50 (rat): 970 mg/kg; Dermal LD50 (rabbit): >2000 mg/kg
Skin Corrosion/Irritation: Causes moderate skin irritation
Serious Eye Damage/Irritation: Causes moderate to severe eye irritation
Respiratory Sensitization: Possible respiratory irritant, may induce coughing and shortness of breath
Skin Sensitization: May cause allergic reactions in certain individuals
Germ Cell Mutagenicity: None known
Carcinogenicity: Not classified as a human carcinogen by IARC, NTP, OSHA
Reproductive Toxicity: No data available, not expected to cause reproductive harm
Target Organ Effects: Prolonged exposure may impact mucous membranes, respiratory system, skin, eyes
Other: Symptoms include redness, itching, nausea, and gastrointestinal discomfort
Ecotoxicity: Harmful to aquatic life in significant concentrations, LC50 for fish (96h): ~283 mg/L
Persistence and Degradability: Biodegradable with time, but may persist in quantity
Bioaccumulative Potential: Low potential for bioaccumulation
Mobility in Soil: Moderate, soluble in water
Other Adverse Effects: Avoid release into environment, do not discharge into lakes, streams, or sewers
Decomposition Products: Not expected to produce persistent harmful products in the environment
Disposal Methods: Dispose as hazardous chemical waste in accordance with local, state, federal regulations
Contaminated Packaging: Triple rinse, dispose of containers following local guidelines
Special Precautions: Do not dispose of product or waste via domestic sewage, ensure disposal at an authorized chemical waste site
UN Number: Not classified as dangerous goods for transport
UN Proper Shipping Name: Not regulated
Transport Hazard Class: Not applicable
Packing Group: Not regulated
Environmental Hazards: Not classified as marine pollutant
Special Precautions for User: Prevent bulk spillage, use secure and sealed packaging during transport
Regulatory Information: Generally shipped in accordance with chemical safety guidelines for laboratory and industrial chemicals
TSCA: Listed
DSL/NDSL (Canada): Listed
REACH (EU): Registered and compliant for industrial and professional use
OSHA Hazards: Irritant
SARA Title III (Sections 302/311/312/313): Not subject to reporting
California Proposition 65: Not listed
Other National Regulations: Consult country-specific information for handling, use, and restrictions
International Inventories: Listed on main global chemical inventories
