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Product Name: Hydroxylamine Hydrochloride
Chemical Formula: NH2OH•HCl
Synonyms: Hydroxylammonium chloride
Recommended Use: Laboratory reagent, intermediate in chemical synthesis
Manufacturer: Provided by chemical supplier
Emergency Contact: Refer to the supplier’s emergency hotline
CAS Number: 5470-11-1
UN Number: 2923
EC Number: 226-798-2
Hazard Statements: Irritating to eyes, respiratory system, and skin; May cause allergic skin reaction; May cause methemoglobinemia; Harmful if swallowed or inhaled; Suspected of causing genetic defects; Possible environmental hazard
GHS Classification: Acute Toxicity Oral Category 3; Skin Irritant Category 2; Eye Irritant Category 2A; Skin Sensitization Category 1
Pictogram: Skull and crossbones, exclamation mark, health hazard
Signal Word: Danger
Precautionary Statements: Avoid inhalation; Wear gloves and eye protection; Use respiratory protection; Do not eat, drink, or smoke during use; Handle in a well-ventilated place; Wash exposed areas thoroughly after handling
Potential Health Effects: Causes irritation and possible burns to skin, eyes, and mucous membranes; May affect blood and cause cyanosis
Chemical Name: Hydroxylamine Hydrochloride
Concentration: 99% or higher
Impurities: Trace amounts of water or residual manufacturing agents
Molecular Weight: 69.49 g/mol
Ingredient Disclosure: No other hazardous components present above threshold limits
Inhalation: Remove to fresh air immediately; Keep person warm and at rest; Obtain medical attention if symptoms develop; Provide oxygen if breathing is difficult
Skin Contact: Remove contaminated clothing; Wash exposed skin thoroughly with soap and water; Seek medical attention if irritation persists or allergic reaction occurs
Eye Contact: Rinse eyes cautiously with water for at least 15 minutes, holding eyelids apart; Seek immediate medical attention
Ingestion: Do not induce vomiting; Rinse mouth with water; Seek immediate medical advice; Never give anything by mouth to an unconscious person
Note to Physician: Treat symptomatically; Monitor for possible methemoglobinemia; Provide supportive care as required
Suitable Extinguishing Media: Water spray, dry chemical, CO2, foam
Unsuitable Extinguishing Media: Avoid high-pressure water streams as they may spread spilled material
Specific Hazards: Thermal decomposition produces toxic and irritating fumes; Nitrogen oxides, hydrogen chloride, and ammonia may form
Special Protective Equipment: Firefighters should use self-contained breathing apparatus and full protective gear
Firefighting Guidance: Move containers away from fire area if it can be done safely; Cool exposed containers with water spray; Evacuate area in case of large fire
Personal Precautions: Evacuate unnecessary personnel; Ventilate area; Wear chemical-resistant gloves, safety glasses, and suitable protective clothing
Spill Cleanup Methods: Collect spilled material with inert absorbent; Shovel or sweep into properly labeled waste container; Wash affected area with copious water
Environmental Precautions: Prevent entry into drains, watercourses, and soil; Alert environmental authorities if significant spills occur
Decontamination: Neutralize with sodium bisulfite if appropriate; Use dilute vinegar as a secondary wash if standard neutralizing agents are unavailable
Handling Practices: Use only in well-ventilated areas; Avoid contact with skin, eyes, and clothing; Avoid inhalation of dust; Handle away from heat, sparks, and sources of ignition
Storage Conditions: Store in tightly sealed containers; Keep away from incompatible materials (oxidizing and reducing agents, acids, bases); Store in a cool, dry, well-ventilated place
Hygiene Measures: Do not eat, drink, or smoke in areas of use; Wash hands thoroughly after working with the substance; Provide safety showers and eyewash stations nearby
Exposure Limits: No OSHA PEL or ACGIH TLV established; Use good industrial hygiene practice to minimize exposure
Engineering Controls: Use local exhaust ventilation; Maintain negative pressure in handling areas
Personal Protective Equipment: Protective gloves (nitrile or neoprene), safety goggles, lab coat or chemical apron, respiratory protection as warranted by risk assessment (preferably NIOSH-approved respirator)
Environmental Controls: Prevent chemical release into drains or water systems; Use spill trays and secondary containment
Appearance: White crystalline solid
Odor: Slight ammonia-like
Melting Point: 151°C (decomposes)
Boiling Point: Decomposes before boiling
Solubility: Highly soluble in water, soluble in ethanol
pH (1% solution): ~2.0
Density: Approx. 1.67 g/cm3
Vapor Pressure: Not significant at 20°C
Evaporation Rate: Not applicable
Flash Point: Not flammable under typical conditions
Decomposition Temperature: Above 151°C forms toxic gases
Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: May react vigorously with strong oxidizers, reducers, acids, and bases
Hazardous Decomposition Products: Nitrogen oxides, hydrogen chloride, ammonia, and other toxic gases
Polymerization: Does not undergo hazardous polymerization
Other Incompatibilities: May react with most metals under certain conditions; Keep away from combustible materials
Likely Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Effects: Eye and skin irritation, respiratory irritation, headache, nausea, methemoglobinemia (blue tinge to lips and skin), possible allergic reactions
Chronic Effects: Repeated exposure may cause allergic contact dermatitis, blood effects such as anemia, possible genetic mutation risk based on animal studies
Toxicity Data: Oral rat LD50: 141 mg/kg; Skin rabbit LD50: 550 mg/kg
Carcinogenicity: Classified as not classifiable for carcinogenicity by major agencies
Other Information: May cause sensitization in susceptible individuals
Aquatic Toxicity: Harmful to aquatic life with long-lasting effects; Acute exposure can cause toxicity in fish, daphnia, and algae
Persistence and Degradability: Readily biodegradable by standard wastewater treatments, though high discharge concentrations may impact water quality
Bioaccumulative Potential: Not expected to significantly bioaccumulate
Mobility in Soil: Highly soluble; May migrate in soil and groundwater
Other Adverse Effects: Released product may contribute to eutrophication if discharged in large quantities
Waste Disposal Methods: Collect and contain material for disposal at a licensed hazardous waste facility; Follow local, national, and international regulations
Container Disposal: Rinse empty containers with water, neutralize residue, dispose as hazardous waste
Precautions: Do not discharge untreated waste into waterways or sewers
Recommended Treatment: Use appropriate neutralization and chemical waste management; Consult with waste disposal professionals for large quantities
UN Number: 2923
Proper Shipping Name: Toxic solid, corrosive, inorganic, n.o.s. (Hydroxylamine Hydrochloride)
Transport Hazard Class: 6.1 (Toxic), 8 (Corrosive)
Packing Group: II
Marine Pollutant: Not classified as marine pollutant
Label Requirements: Toxic, Corrosive
Special Precautions: Securely package containers; Ship in accordance with all applicable transport regulations for road, rail, air, and sea transport; Provide documentation and emergency instructions
TSCA Inventory: Listed
REACH Status: Registered or pre-registered
SARA Title III (Sections 302/313): Not listed as extremely hazardous or as a TRI chemical
OSHA Classification: Hazardous chemical
WHMIS Classification (Canada): Toxic, Corrosive
Other National Regulations: Subject to workplace safety and chemical control measures in most jurisdictions
Labeling Requirements: Comply with local and national regulations for containers, storage, and hazard communication
Additional Notes: Users should stay updated on changing regulatory requirements relevant to workplace exposure, labeling, and waste management
