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Product Name: Potassium Hydrogen Phthalate
Synonyms: KHP, Monopotassium phthalate
Molecular Formula: C8H5KO4
Molecular Weight: 204.22 g/mol
CAS Number: 877-24-7
Recommended Use: Analytical reagent, buffer in laboratory settings
Supplier: Provide contact information for supplier or manufacturer as required by safety regulations
Emergency Phone: Emergency contact number according to regional requirements
GHS Classification: Not classified as a hazardous chemical by GHS criteria
Main Hazards: Can cause mild skin and eye irritation on contact; ingestion may lead to gastrointestinal discomfort; not known to be flammable; dust may be mildly irritating if inhaled
Signal Word: None
Hazard Statements: Causes slight irritation to eyes and skin; may cause respiratory irritation in dust form
Precautionary Statements: Avoid breathing dust, wash hands thoroughly after handling, avoid contact with eyes and prolonged skin contact
Chemical Name: Potassium Hydrogen Phthalate
Concentration: 99-100%
CAS Number: 877-24-7
EINECS Number: 212-898-2
Impurities and Stabilizing Additives: No relevant hazardous impurities present in typical analytical grade material; always check individual supplier certificate of analysis for trace component content
Eye Contact: Rinse cautiously with water for several minutes; if irritation persists, seek medical advice
Skin Contact: Wash affected area with soap and water; remove contaminated clothing and launder before reuse
Inhalation: Move to fresh air; seek medical attention if respiratory symptoms develop or persist
Ingestion: Rinse mouth with water; do not induce vomiting unless directed by medical personnel; seek medical advice if there are symptoms
Notes for Medical Personnel: Treat symptomatically, monitor for allergic reaction, no specific antidote reported
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Unsuitable Extinguishing Media: None known for this substance
Specific Hazards: Not flammable under normal conditions; thermal decomposition may yield carbon oxides and potassium compounds
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and full protective gear; approach from upwind and prevent contact with skin and eyes
Firefighting Instructions: Cool surrounding containers with water spray; contain runoff to prevent entry into water systems
Personal Precautions: Ventilate area, wear suitable protective clothing (gloves, goggles, mask); avoid creating airborne dust
Environmental Precautions: Prevent large spills from entering drains, sewers, or watercourses; notify authorities as required
Cleanup Methods: Sweep up using tools that minimize dust generation, collect in appropriate containers for disposal; wash area with water after cleanup is complete
Handling: Use in ventilated areas to prevent dust accumulation; avoid breathing dust and avoid contact with eyes and skin; no eating, drinking, or smoking near work area
Storage: Store tightly closed in well-ventilated, cool, dry place; keep away from strong acids, bases, or oxidizing agents; segregate from incompatible substances and avoid conditions that may produce dust; label containers clearly
Occupational Exposure Limits: No established national occupational exposure limits for this substance; general dust control threshold (particulate not otherwise classified) typically used
Engineering Controls: Ensure good local exhaust and general ventilation; use process enclosures, local exhaust, or other engineering controls to reduce airborne dust
Personal Protective Equipment: Use protective gloves (nitrile or neoprene recommended), safety goggles; use dust mask or respirator if airborne particulates are likely; wear lab coat or protective clothing to prevent skin contact
Hygiene Practices: Wash hands before breaks and after handling; do not allow food, drink, or tobacco in work area
Appearance: White crystalline solid
Odor: Odorless
Melting Point: 295°C (with decomposition)
Boiling Point: Not applicable (decomposes before boiling)
Density: Approximately 1.636 g/cm³
Water Solubility: 20g/100mL at 25°C
pH (1% solution): 4.0 - 5.0
Partition Coefficient: Not available
Vapor Pressure: Negligible at room temperature
Flash Point: Not flammable
Evaporation Rate: Not applicable
Chemical Stability: Stable under normal storage and handling conditions
Reactivity: Not reactive under standard conditions; avoid strong acids, bases, or strong oxidizers
Conditions to Avoid: Excessive heat, moisture, sources of ignition
Hazardous Decomposition Products: May produce carbon monoxide, carbon dioxide, and potassium compounds on thermal decomposition
Polymerization: Hazardous polymerization does not occur
Routes of Exposure: Skin, eyes, inhalation, ingestion
Acute Toxicity: Low; oral rat LD50 >2000 mg/kg
Skin Irritation: May cause mild, reversible irritation in sensitive individuals
Eye Irritation: May cause mild irritation characterized by redness and discomfort
Inhalation: Inhalation of dust may cause coughing or mild respiratory irritation, rarely significant at typical laboratory concentrations
Ingestion: May produce mild gastrointestinal discomfort (nausea, cramps)
Chronic Effects: Chronic health effects not expected from routine exposure as used in laboratories
Carcinogenicity: Not listed as a carcinogen by IARC, NTP, ACGIH, or OSHA
Mutagenicity / Reproductive Hazard: No evidence of mutagenicity or reproductive toxicity in available studies
Persistence and Degradability: Readily soluble; not expected to persist
Bioaccumulation Potential: Potassium and phthalate ions do not accumulate significantly in organisms
Aquatic Toxicity: Not acutely toxic to aquatic life; very high concentrations may temporarily alter pH in small bodies of water
Mobility in Soil: High solubility and mobility in water
Other Adverse Effects: No known significant environmental hazards when handled and disposed of appropriately
Waste Disposal Methods: Dispose in accordance with local, regional, and national environmental regulations; small laboratory quantities can often be washed down the drain with large volumes of water unless prohibited
Container Disposal: Rinse containers and dispose as non-hazardous laboratory glassware or plastic as specified by regulatory policies
Special Precautions for Landfill or Incineration: Avoid disposal into natural water sources; incinerate only in an approved facility if required; always use authorized waste disposal contractors when handling bulk waste
UN Number: Not regulated under UN Model Regulations for transport
Proper Shipping Name: Not regulated; ship as laboratory chemical or chemical substance
Transport Hazard Class: Not classified as hazardous for road, air, or sea transport
Packing Group: Not applicable
Environmental Hazards: Not a marine pollutant
Special Precautions: Transport in sealed containers to minimize risk of spillage and dust creation
TSCA Inventory Status: Listed
DSL/NDSL (Canada): Listed
REACH (EU): Exempted or registered; check current compliance status
OSHA Status: Not hazardous under OSHA regulations
SARA Title III: Not subject to reporting; does not contain reportable ingredients
WHMIS (Canada): Not classified as risky or toxic
Other National Regulations: Meets basic safety requirement for use as laboratory chemical; always review local and country-specific chemical safety and environmental requirements
