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Product Name: Hederacoside C
Chemical Family: Saponin glycoside
Molecular Formula: C53H86O22
Recommended Use: Laboratory research, pharmaceutical development
Synonyms: Ivy saponin C, α-Hederin-28-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranoside
Supplier: Name, address, and contact details of relevant supplier
CAS Number: 465-99-6
Emergency Contacts: Relevant local poison control center, fire brigade contact number, in-house workplace safety supervisor’s contact
Classification: Hazardous material under GHS, Eye irritation, Skin irritation, Specific target organ toxicity-single exposure; oral toxicity
GHS Signal Word: Warning
Hazard Statements: May cause moderate skin and eye irritation, may be harmful if swallowed, potential for mild respiratory irritation on inhalation of powder or dust forms
Pictograms: Exclamation mark indicating irritancy and health hazard
Precautionary Statements: Avoid breathing dust, wash skin thoroughly after handling, keep away from food or drinks
Potential Health Effects: Eye reddening, contact dermatitis, mild mucous membrane irritation, rarely stomach upset if ingested in significant amount
Emergency Overview: White to off white powder or solid; not expected to present explosive hazard but form dust clouds under intense agitation; not acutely toxic in small amounts handled with lab gear
Chemical Name: Hederacoside C
CAS Number: 465-99-6
Purity: ≥ 98% by HPLC
Impurities: Trace amounts of Hederacoside B and other related saponins (≤2%)
Other Components: None significant for safety classification
Inhalation: Move affected person to fresh air, support breathing as needed, consult medical professional if symptoms persist
Skin Contact: Remove contaminated clothing and flush skin with water and mild soap for 15 minutes, watch for delayed irritation
Eye Contact: Rinse cautiously with water for several minutes, holding eyelids open, seek attention if irritation persists
Ingestion: Rinse mouth thoroughly, drink small amount of water if person is conscious, avoid inducing vomiting unless instructed by health professional, monitor for gastrointestinal symptoms
Advice to Physicians: Symptomatic treatment; no specific antidote known for Hederacoside C exposure
Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical, foam
Specific Hazards: Combustion byproducts may include carbon oxides and minor amounts of organic fumes
Protective Equipment: Self-contained breathing apparatus, protective gloves, flame resistant coat
Special Procedures: Isolate from sources of ignition; use caution to avoid powder dispersion in air to prevent dust explosion potential
Unusual Fire and Explosion Hazards: Dust clouds may ignite under exceptional conditions of static electricity or open flame, but risk is low in typical lab settings
Personal Precautions: Use gloves and safety goggles, avoid breathing dust, ventilate area
Environmental Precautions: Avoid uncontrolled discharge to drains or natural water bodies, collect spills to prevent spread
Methods for Containment: Gently cover and scoop up powder, place in sealed labeling waste containers
Cleanup Procedures: Use damp cloth or vacuum with HEPA filter to collect residue, dispose as per regulations, ventilate and wash affected area with soap and water after cleanup
Handling: Work in well-ventilated space, avoid generating dust, wear personal protection such as lab coats, goggles, and gloves
Storage Conditions: Keep container tightly closed, store in cool, dry, and well-ventilated area away from sunlight, incompatible materials include strong oxidizers
Hygiene Practices: Wash hands after use, separate food and drink from working area, discard single-use gloves and clean equipment after work
Exposure Limits: No established occupational limit for Hederacoside C; treat as nuisance particulate with recommended threshold of 10 mg/m³ (inhalable dust)
Engineering Controls: Use fume hood or local exhaust to control airborne dust
Personal Protective Equipment: Wear gloves (nitrile or latex), laboratory safety glasses or goggles, lab coat, dust mask or superior particulate respirator if airborne concentration rises
Additional Protection: Emergency eyewash and safety shower facilities in immediate working area
Appearance: White to off white crystalline powder
Odor: None to mild, plant-like
Odor Threshold: Not available
Molecular Weight: 1119.23 g/mol
Melting Point / Freezing Point: Decomposes before melting (around 210 °C)
Boiling Point: Not applicable (decomposes on heating)
Solubility: Soluble in water, sparingly soluble in methanol, insoluble in hexane
pH: Neutral to slightly acidic, 5.5–7 (1% solution in water)
Partition Coefficient (octanol/water): Not determined
Vapor Pressure: Not applicable
Evaporation Rate: Not applicable
Flash Point: Not determined (not volatile)
Chemical Stability: Stable under standard handling and storage conditions
Conditions to Avoid: Heat, flame, direct sunlight, moisture ingress
Incompatible Materials: Strong oxidizers, concentrated acids
Decomposition Products: Burning produces oxides of carbon and low molecular weight organic compounds
Hazardous Reactions: Polymerization does not occur under normal conditions
Acute Toxicity: Data limited; estimated oral LD50 in rodents > 2000 mg/kg (low acute toxicity)
Skin Corrosion/Irritation: Mild, reversible irritation on prolonged exposure
Serious Eye Damage/Irritation: Redness and watering after direct contact
Respiratory Sensitization: Not documented; dust may cause coughing or mild discomfort
Germ Cell Mutagenicity: No mutagenic effects observed in standard Ames tests
Carcinogenicity: No evidence on carcinogenicity from available studies
Reproductive Toxicity: Not classified as reproductive hazard, based on structurally similar compounds
Specific Target Organ Toxicity — Single Exposure: May cause moderate gastrointestinal or mucous membrane discomfort
Specific Target Organ Toxicity — Repeated Exposure: No data suggest chronic risk with normal handling and laboratory exposure
Aquatic Toxicity: Not acutely toxic to aquatic species in standard laboratory tests, no expected bioaccumulation
Biodegradability: Organic saponin class, readily biodegradable in standard aerobic soil and water assays
Mobility in Soil: Moderately mobile, water soluble, low volatility
Persistence and Degradability: Rapid breakdown via soil and water microflora
Other Adverse Effects: No ozone depletion, photochemical smog, or long range environmental transport expected
Waste Treatment Methods: Absorb with inert dry material and dispose of in chemical waste container; incineration preferred over landfill
Disposal of Containers: Triple rinse and offer for recycling or incineration if not reusable
Precautions: Avoid releasing powders to water systems, use local regulations for hazardous chemical disposal
UN Number: Not assigned, not classified as hazardous for transport by road, air, or sea under typical international conventions
Shipping Name: Non-hazardous organic solid, not otherwise specified
Transport Hazard Class: Non-hazardous
Packing Group: Not regulated
Environmental Hazards: Does not require environmentally hazardous substance notation
Special Precautions: Keep container sealed, upright, avoid rough handling during shipment
TSCA (USA): Not listed
EINECS (EU): Not listed
REACH Status: Exempt as naturally occurring substance with no hazardous use
OSHA Classification: Hazardous chemical as per OSHA Hazard Communication Standard
WHMIS (Canada): Considered non-controlled
California Proposition 65: Not listed
RoHS/ELV: Not applicable
Other regulations: Observe local, regional, and national standards for chemical storage, handling, disposal, and reporting
