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Diving Deep into Glycine Methyl Ester Hydrochloride: Past, Present, and Where We Go Next

Tracing the Historical Roots

People have sought clever solutions in chemistry for generations, but progress doesn’t always run in a straight line. Glycine methyl ester hydrochloride has a backstory that demonstrates the problem-solving mindset of those early researchers. Before chemical synthesis made life easier for many fields, glycine’s discovery set off years of work to tweak and refine derivatives for both medicine and materials science. By the 20th century, chemists realized that methylating glycine, then transforming it into the stable hydrochloride salt, allowed for easier handling and purer results. This form fit into laboratories and manufacturing processes as a reliable building block. The modern chemical industry often builds on these decades-old breakthroughs, not only rediscovering their utility but taking them further with smarter processes and ambitious applications.

What Sets the Product Apart

Glycine methyl ester hydrochloride isn’t something most folks encounter in daily life, yet its simplicity masks a valuable versatility. The compound combines a basic amino acid backbone with a methylated ester, tamed with a touch of hydrochloric acid. That gives it a white crystalline appearance, good water solubility, and reliable shelf stability. Unlike some other reagents that can turn unpredictable or volatile, glycine methyl ester hydrochloride keeps its cool—for folks in the lab, that means fewer headaches and more consistent results. My own work with the material left me respecting how cleanly it behaves under the usual synthetic routines. It offers a recognizable, sharp melting point, so you spot impurities quickly or catch mistakes in preparation. The hydrochloride form helps chemists avoid the strong odors or degradation often seen with free esters, which matters if you care about clean bench tactics and reliable batch work.

Physical and Chemical Properties for the Real World

Sometimes in the hunt for new drugs or industrial materials, a single compound’s physical profile can make or break a project. Glycine methyl ester hydrochloride holds up well thanks to its straightforward chemistry. Its moderate molecular weight fits most organic synthesis protocols, especially peptide coupling and small-molecule modification. The white crystalline powder dissolves fast in water—no long waits or clumps—so dosing for reactions works without much fuss. The odor is faint and barely noticeable, a pleasant change for anyone used to working around sulfur or amine-laden reagents. The compound resists decomposition under standard storage and shows low risk of spontaneous reaction when stored correctly. Handling this material feels much safer than juggling more temperamental starter compounds.

Diving into Technical Specs and Product Labeling

For anyone running a tight ship in a research lab or production plant, straight facts matter most. Labels on glycine methyl ester hydrochloride generally provide batch number, production date, purity percentage, and warnings. Most suppliers guarantee a minimum purity in the high nineties, which matches what’s needed for advanced synthesis and peptide assembly. Impurities get flagged early thanks to reliable spectroscopic markers—clear IR and NMR signals, well defined melting points—so quality assurance can run checks without expensive guesswork. Even after years in the field, I find that a well-labeled bottle of glycine methyl ester hydrochloride gives peace of mind. You know what you’re dealing with; you know how it should perform.

Preparation Method: Precision Pays Off

Glycine methyl ester hydrochloride doesn’t pop up in nature. Its preparation usually takes one of two routes—direct methylation of glycine in an acid environment or a Fischer esterification followed by salt formation. The more efficient methods favor milder conditions to improve safety and cut down on harsh by-products. I’ve sat in on enough synth labs to appreciate when researchers adjust pH and proportions carefully, catching the cleanest conversion and happiest product isolation. Organic solvents see limited use, especially for large-scale runs, but water keeps environmental costs in check for many operations. When handled right, the process turns out a solid product needing minimal cleanup, saving both time and resources. Environmental pressures have nudged the industry to develop greener protocols, with catalysts and milder acids getting more attention these days.

Chemical Reactivity and Modifications

If you like tinkering, glycine methyl ester hydrochloride lets you be creative. Its ester group opens doors for further chemical elaboration, such as protecting and coupling steps that form richer molecules. In peptide synthesis, the methyl ester group shields the carboxylic acid until you’re ready to free it, helping avoid side reactions and unwanted byproducts. I’ve used it for custom peptide chains—the hydrochloride salt keeps it from going off course, and it doesn’t jump into unexpected side reactions, saving hours of troubleshooting. Its amine group lets you tag on a wide range of protecting groups, making it versatile in developing complex molecules from anticancer candidates to enzyme inhibitors. Modifications rarely pose headaches since the product's purity and stability give researchers a consistent canvas for molecular creativity.

The Many Names Glycine Methyl Ester Hydrochloride Carries

Chemists often play name games as compounds drift from laboratory benches to industrial catalogs. Glycine methyl ester hydrochloride pops up under a range of synonyms, including N-methoxycarbonylglycine hydrochloride and methyl aminoacetate hydrochloride. Catalogs might shorten the name further or reference structural descriptions. The multiplicity of names can trip newcomers, but seasoned researchers check the CAS number and core chemical structure for clarity. Once you learn the names, confusion drops off and sourcing gets much quicker—even across global suppliers. For me, the different names tell a story of evolving chemistry, commerce, and regulation, each adding to the compound’s history.

Keeping It Safe and Following the Rules

No good comes from cutting corners on safety when dealing with chemicals, even those thought of as low risk. Glycine methyl ester hydrochloride falls on the safer end compared to volatile organic solvents or tough acids, yet basic protocols deserve respect: gloves, good ventilation, and clear labeling limit the chance for accidents. In teaching labs, I’ve seen experienced hands walk newcomers through safe dispensing, proper waste handling, and what to do if spills occur. Eye protection stays mandatory since irritation risk rises with hydrochloride salts. Storage in sealed, moisture-free containers avoids nasty surprises—a point stressed in every lab’s safety orientation. Regulatory agencies have weighed the toxicity risk and placed glycine methyl ester hydrochloride well below more hazardous reagents, but this doesn’t mean safety slip-ups can be shrugged off. Over the years, institutional audits and third-party certifications have raised the baseline standards across the chemical industry, nudging even smaller operations toward more rigorous practices.

Where Glycine Methyl Ester Hydrochloride Finds Purpose

While its formula looks unimposing, glycine methyl ester hydrochloride supports a surprising range of applications. By far its largest home sits within peptide and protein research. Drug developers count on the compound for streamlined peptide bond formation and robust protection strategies during combinatorial chemistry. Beyond drug labs, plant biologists, enzymology researchers, and materials scientists harness the molecule’s backbone for new biomaterials and as a key intermediate in specialty polymers. My own projects explored its use in linking nano-structures for biosensors, where the clean reactivity and predictable outcomes give it an edge. Academic chemistry benefits too: glycine methyl ester hydrochloride routinely shows up in advanced organic teaching labs to demonstrate synthesis steps and product purification. Every year, colleagues unearth new tweaks and uses, strengthening its role as a foundation for exploring tougher chemical puzzles.

Research Focuses and Progress in the Lab

Innovation doesn’t slow down. In the past decade, researchers have turned to glycine methyl ester hydrochloride as a cornerstone for creating new peptide drugs targeting previously untreatable diseases. Studies published in major journals describe how its stability boosts yields and slims down purification steps, especially in automated synthesizers now common in pharma research. Green chemistry champions have tackled ways to reduce waste by fine-tuning reaction solvents and designing closed-loop synthesis that capture byproducts for reuse. Across Asia and Europe, collaborative projects see the molecule tested in trickier nucleotide and protein modification, as well as custom ligands for catalysis. Over coffee in faculty lounges, scientists debate the next big leap—many aim to graft functionalized glycine methyl esters into polymer backbones, chasing stronger, smarter biomaterials for medical devices or environmentally friendly agricultural products.

The Latest Thinking on Toxicity and Health Effects

Every chemist worth their salt pays attention to toxicity—even modest risks demand scrutiny with so much on the line. Over the years, glycine methyl ester hydrochloride has undergone a battery of toxicity evaluations. Acute oral and dermal toxicity ranks low, with limited systemic absorption reported in animal studies. Contact with eyes or sensitive skin can cause irritation, justifying basic protection, but standing hazards like mutagenicity or longer-term carcinogenic potential haven’t shown strong evidence in standard models. That said, nobody in the safety business takes reputation as a guarantee. Each new use or modification restarts assessment, and regulatory bodies require fresh data for any new pharmaceutical applications. I share these lessons with my students: every material deserves respect, even those that seem benign, and reliable data beats complacency every time.

Looking to the Horizon: Future Possibilities

New stories often begin with basic building blocks. Glycine methyl ester hydrochloride has moved from the back shelves of stockrooms to a more visible role on the front lines of molecular innovation. The compound’s utility in bioconjugation, green synthesis, and peptide therapeutics keeps growing as demand for targeted drugs and degradable plastics rises. Artificial intelligence now scours chemical databases, proposing modifications and new application arenas for familiar molecules. Some teams hope to automate high-throughput synthesis, linking glycine methyl ester hydrochloride to a cascade of designer products in fields as wide as energy harvesting, antimicrobials, and sustainable reagents. I hear from colleagues in both academia and startup circles who see the molecule as a launchpad for the next wave in chemical and pharmaceutical research, buoyed by its predictable performance and gentle handling profile. The lesson is clear: even tried-and-true compounds can set the stage for breakthroughs, especially when curiosity and rigor shape the direction.




What is Glycine Methyl Ester Hydrochloride used for?

What Makes Glycine Methyl Ester Hydrochloride Useful?

Glycine methyl ester hydrochloride shows up often in chemistry labs and manufacturing for a reason. This compound, a modified form of the simple amino acid glycine, plays a unique role because it combines two versatile chemical groups. On one end, there’s the amino acid backbone that links easily with other molecules. On the other, the methyl ester and hydrochloride groups change its solubility, making it easier to handle in lab settings.

People in organic chemistry appreciate how quickly glycine methyl ester hydrochloride forms peptide bonds. When researchers work on building short chains of amino acids—key steps in making new drugs or studying proteins—they turn to this compound. Its efficiency saves time and cuts down waste. In the race to develop new medicines, fast and reliable building blocks matter a lot.

Applications in Research and Industry

This compound shows up in many pharmaceutical labs. Scientists synthesizing new molecules for cancer treatments and antibiotics often start with basic structures such as glycine methyl ester hydrochloride. Its chemical properties help build larger molecules without unwanted side reactions. As someone who worked in a pharmaceutical analytics lab, I saw chemists prefer it for high-purity peptide synthesis.

Outside research, companies look to glycine methyl ester hydrochloride for manufacturing specialty chemicals. For example, it acts as an intermediate when making novel agrochemicals or custom polymers. Quick reactions help save both time and resources. In specialty plastics and coating industries, this efficiency can bring down costs, and those savings can pass to other links in the chain—like farmers or electronics makers.

Safety and Handling Concerns

In my own experience around lab benches, safety protocols make a difference. Glycine methyl ester hydrochloride, while less reactive than harsher chemicals, still demands respect. It can cause skin and eye irritation, and inhaling the powder is not a good idea. Gloves, dust masks, and eye protection should always stay within reach. Chemical suppliers share detailed safety sheets for a reason, and skipping steps increases risk. Lab workers trained to value preparation wind up preventing costly injuries or product losses.

The Push for Greener Chemistry

Glycine methyl ester hydrochloride has another interesting angle: the push for greener, more sustainable chemistry. Traditional peptide synthesis sometimes relies on environmentally harmful solvents or produces lots of chemical waste. Newer approaches aim to cut down on waste, using water-based reactions and safer solvents. This compound’s stability under milder conditions fits well with these efforts. Some research teams are even developing processes to recycle parts of the molecule, reducing environmental impact even further.

Potential Solutions to Common Challenges

One headache in the lab comes from keeping glycine methyl ester hydrochloride stable during storage. Moisture can cause it to break down, sometimes ruining an expensive batch. Sealed, airtight packaging and careful humidity control help here. Better packaging strategies, like vacuum-sealed pouches, often make a surprising difference in preventing spoilage and saving resources.

Scaling up from small research batches to industrial production brings its own problems. Cross-contamination can kill a batch quickly. Dedicated lines and strict cleaning protocols reduce that risk. Some companies invest in on-site testing equipment to catch problems early, catching errors before things spiral out of control.

Looking Forward

From pharmaceuticals to specialty manufacturing, glycine methyl ester hydrochloride won’t drop out of favor anytime soon. Factories and universities rely on its reactivity, and researchers appreciate how it streamlines workflows. If industry and academia keep finding smarter and more sustainable ways to use and produce it, the benefits will reach far beyond the lab bench. Maybe the next big breakthrough in medicine or agriculture will owe a debt to this unassuming white powder.

What is the chemical formula of Glycine Methyl Ester Hydrochloride?

Chemical Formula and Molecular Details

Glycine methyl ester hydrochloride is a chemical compound with the formula C3H8ClNO2. The structure holds a methyl ester derivative of glycine, paired with a hydrochloride group. The hydrochloride not only boosts the compound's stability in solid form but also makes it more soluble in water. This ease of dissolution sits at the heart of why so many researchers prefer it for lab work.

The backbone comes from glycine, one of the body's simplest amino acids. By attaching a methyl group to its carboxyl side, chemists create a version more reactive for organic synthesis. The hydrochloride attachment helps keep it from absorbing moisture from the air. For those working in peptide chemistry, this small change saves plenty of frustration.

Where It Makes a Difference

In the real world, nobody wins prizes for memorizing chemical formulas. What gets noticed is how substances like glycine methyl ester hydrochloride push science forward. In peptide synthesis, it acts as a starting block. The methyl ester side reacts well with agents that link amino acids together in sequences—useful for building new proteins and exploring disease treatments.

Researchers rely on accurate materials when mapping out new drugs or diagnostic molecules. A mistake in the formula or impurity causes entire projects to stumble. C3H8ClNO2 brings consistency, and reliable batches allow scientists to repeat experiments and compare outcomes. This lines up well with principles of reproducibility. Modern science thrives on these solid foundations; patient lives and well-funded studies both depend on the smallest details being right.

Understanding chemical formulas means more than recognizing a string of letters and numbers. The arrangement of atoms—carbon, hydrogen, chlorine, nitrogen, and oxygen—decides both functionality and safety. The chlorine atom offers a steady bond that limits excessive reactivity, avoiding unwanted side reactions in sensitive experiments. Each piece carries weight, and swapping a hydrogen or losing an oxygen molecule can shift results dramatically.

Supporting Discovery and Innovation

Building on the basics, chemistry classrooms often use compounds like glycine methyl ester hydrochloride to ground abstract concepts. This hands-on approach pays off later when students step into labs or join biotech startups. Having mixed real chemicals, they grasp the risks and pay-offs of synthesis much better than from textbooks alone. Teachers gain an ideal candidate for demonstrating acid-base reactions and ester formation—core activities needed in the wider world.

Supply chain reliability also marks a make-or-break factor. Any issue with purity, storage, or labeling can endanger research. Quality control remains key. Trusted suppliers now provide detailed certificates of analysis so scientists know what sits inside each container. Mistakes become costly, not just in dollars but in trust and wasted time. Rigid checks and regulatory frameworks protect investments and keep workplaces safe.

For any lab, accurate chemicals like glycine methyl ester hydrochloride keep routines smooth, discoveries frequent, and results meaningful. Understanding their formulas, structures, and real-world roles sets the stage for smarter science and safer solutions for society’s biggest challenges.

How should Glycine Methyl Ester Hydrochloride be stored?

Everyday Life Meets Chemistry

Glycine methyl ester hydrochloride isn’t just another academic name in a catalog; it’s a compound some researchers and industry folks rely on, often keeping it quietly tucked away in storerooms or lab cabinets. I’ve worked with countless reagents over the years, and I can tell you straight up—handling these chemicals isn’t just about knowing a formula. It’s about protecting the people around you, and stopping costly mistakes long before they happen.

From my own years in the lab, I know that simple steps make the biggest difference. Problems rarely explode in dramatic fashion—most start small, from neglecting simple storage instructions or not checking labels. That’s how corrosion creeps up, or a reagent suddenly gives out an odd smell that nobody remembers reading about. Letting your guard down over storage isn’t just careless, it’s avoidable trouble.

The Role of Temperature and Moisture Control

I’ve seen what happens when chemicals mix with humidity. Glycine methyl ester hydrochloride can draw in water from the air, clumping up and breaking down way ahead of schedule. Fine, white crystals turn sticky, and the next thing you know, your experiment concludes with a whimper instead of a bang. This loss in quality isn’t just bad news for experiments; it wastes time and money.

Tucking this compound away in a cool, dry, and well-ventilated place should be the norm, not the exception. Standard air-conditioned storage at “room temperature” actually isn’t so standard in many older labs or supply closets. Aim for a climate between 15°C and 25°C. Checking the thermometer regularly helps, as it’s easy for a space to turn into a sauna in the summer or a freezer in the winter.

Choosing the Right Packaging and Containers

The original packaging usually makes the most sense. Manufacturers rely on containers that stand up to the compound’s quirks—resisting acid corrosion, locking out air, and keeping out stray bits of dust. Glass bottles with tight-fitting caps or thick plastic vials usually last best. Those old half-cracked bottles I sometimes see on dusty shelves are a warning sign. Replace worn or leaky lids, and skip makeshift fixes like plastic wrap or tape.

It seems obvious, but labeling makes a difference. Clear, chemical-resistant ink, visible from every angle, keeps confusion at bay. Faded or smeared labels set the stage for accidents or confusion, and those can cost much more than the time it takes to write a new one.

Monitoring and Preventing Contamination

Most problems I see in storage come from cross-contamination. It sneaks up during rushed clean-ups or when someone returns a scoop or spatula without a quick wash. Even a few stray grains of another chemical lead to trouble. Dedicated utensils pay for themselves in peace of mind. Keep tools dry and separate, and leave eating, drinking, or even coffee mugs far from chemical shelves.

Keep a storage log. Small labs may see this as overkill, but a quick jot down every few months flags early problems—unusual clumping, broken seals, or off-color crystals. Early catch means less waste and fewer headaches.

Solutions That Work

On-site training beats dry instruction manuals. It’s one thing reading about safety, and another seeing what a poor seal or a forgotten bottle can do. Share stories of near-misses and real accidents. Making safety personal—by telling what went wrong and how it got fixed—sticks with people.

Quality storage keeps Glycine methyl ester hydrochloride in top shape, protects your work, and cuts down on surprises. It’s worth the effort every single time.

Is Glycine Methyl Ester Hydrochloride hazardous or toxic?

Understanding the Chemical

Glycine methyl ester hydrochloride pops up in university labs and industrial settings especially during peptide synthesis or research involving amino acid derivatives. The structure draws on glycine — the simplest amino acid — altered with a methyl ester group and then stabilized as its hydrochloride salt. People working with it often wear gloves and goggles without thinking too much about it, but questions come up: is this stuff actually hazardous?

What Do We Know About Its Hazards?

The material safety data sheet (MSDS) and the Globally Harmonized System (GHS) hazard communication label are the first stop for anyone who’s handled chemicals. For glycine methyl ester hydrochloride, the MSDS points out a few key things. Direct contact can irritate skin, eyes, and the respiratory system. Short-term exposure doesn’t usually send someone to the ER, but laboratory exposure limits still deserve respect.

On ingestion or inhalation, symptoms like coughing, throat irritation, or abdominal discomfort have come up in the literature. If you’ve ever spent a night with a sore throat after pipetting certain powders, you know how a minor irritant can drag out a workday.

Toxicity in Animals and People

Animal studies put the acute toxicity of glycine methyl ester hydrochloride in a range that classifies it as “harmful” but not brutally toxic. National regulatory agencies rank it lower on the hazard scale compared to many other lab chemicals. LD50 (lethal dose, 50%) data from rat studies fall in a range (several hundred mg/kg) that’s above some solvents but below table salt. Long-term exposure data, as with most research chemicals, remain limited. Chronic effects haven’t shown up in reliable studies, mostly because no one is chomping down milligrams of this compound daily.

Carcinogenicity, mutagenicity, and reproductive risks do not pop up in regulatory databases or academic reports — which lines up with its molecular structure. The chemical groups involved have a clear record in medicine and food chemistry.

Why Handling Still Matters

Risk doesn’t just come from acute toxicity. Dusting off research experience, it’s easy to forget about cross-contamination. Spilled powders can stick to lab benches, equipment, or even gloves, which then travel and later end up near someone’s sandwich in the staff fridge. Even “mild” irritants, left unchecked, can create chronic low-level problems for everyone in a shared space.

In manufacturing, exposure becomes a bigger concern. Large-scale handling means a higher chance for inhalation, accidental splashes, or unintentional spills. Here, skin and respiratory protection become practical, not optional.

Minimizing Hazards

Basic safety rules go a long way. Use nitrile gloves, keep chemical eye protection handy, and store it in a cool, dry spot away from acids and bases. Fume hoods aren’t just overkill; they genuinely cut down on airborne dust that can cause coughs or rashes. In my own lab days, I’ve watched even folks with years on the job get lazy about PPE, only to regret it. Accidents usually happen not because danger lurks, but because shortcuts sneak in.

Label containers, keep spill kits close, and remind colleagues to respect every chemical, even the “low risk” ones. Nobody wants to fill out an incident report over a compound they thought was safe.

Responsibility and Respect

Experience counts in chemical safety. People trust hazard labels and follow manufacturers’ guidance, not just because of rules, but because those small steps keep eyes, lungs, and skin in good shape all year. Glycine methyl ester hydrochloride won’t top any “Most Hazardous” lists, but treating it with respect fits a culture of safety that pays dividends in every lab and warehouse.

What is the purity and grade available for Glycine Methyl Ester Hydrochloride?

Why Purity Makes All the Difference

In labs and factories, quality is king. Every bottle or drum of glycine methyl ester hydrochloride can affect results and products in ways that people don’t always realize. During my time working on custom synthesis projects, I saw how batches just a few tenths of a percent apart in purity could make or break an entire project. This isn’t just a matter of paperwork or ticking off specs on a datasheet—it’s about trust in every gram you open.

Glycine methyl ester hydrochloride doesn’t have a universal, one-size-fits-all grade. Instead, purity most often lands in two main camps: technical grade and high-purity or analytical grade. Technical grade often covers the 97% to 98% range. You’ll find this in manufacturing flows for common chemical transformations, building blocks, or applications where only a minor impurity can be tolerated. In biochemistry, pharmaceutical, or peptide synthesis, suppliers offer purities above 99%. This stuff costs more, but in my experience, even small peptides or complex pharmaceuticals can sputter if the starting material contains low-level contaminants.

Why Analytical Data Counts

People sometimes overlook the certificate of analysis tucked inside a shipment’s paperwork. That certificate spells out what you’re really buying—each batch’s measured purity, moisture, and impurity profile. In reputable suppliers’ documentation, you might see NMR, IR, HPLC, and melting point analysis to back their claims. The HCl salt adds its own layer—without clear specs, there’s room for solvents or other impurities to slip through. I always scan the heavy metals and chloride content lines because these catch the contaminants that throw off reactions or interfere with sensitive downstream processing.

Relevance by Application

Not everyone needs the priciest bottle on the catalog. For example, in large-scale industrial production of simple intermediates, cost control often means sticking with 97% or 98% grade material. My colleagues in peptide chemistry swear by 99%+ for the key steps. I remember a project that used a slightly lower-quality ester and ended up with persistent unknown peaks on the chromatogram. Tracing the problem back to a 1.5% impurity took time and money—always a learning moment.

In pharmaceuticals, regulatory oversight drives demand for near-complete purity and traceability. FDA or EMA filings expect total transparency down to the last decimal place. Analytical-grade glycine methyl ester hydrochloride, meeting or exceeding 99%, matches up with these standards. Labs focused on research, drug development, or analytical chemistry rarely compromise below that line.

Quality Control and Supplier Choice

Choosing a trusted supplier makes all the difference. You notice the difference in packaging, documentation, and support. If a company dodges questions about batch data, or only supplies general statements like “meets specifications,” it raises red flags. Reputable global suppliers—Sigma-Aldrich, Tokyo Chemical Industry, Alfa Aesar—publish lots of technical data. I tend to ask for extra testing on request, especially for custom or sensitive projects, and most established companies will run extra HPLC or moisture tests if you need.

Proper storage also plays a part in preserving purity, not just in the warehouse but at the bench. Moisture can sneak in and alter composition. Even if the raw material leaves the factory at 99.5%, poor handling drops that quickly. Workers at every step—chemists, lab techs, even warehouse staff—must treat the compound with care, using airtight storage and controlled temperatures.

Pushing for Better Standards

Demand keeps rising for clear, honest labelling and traceable sourcing. Today’s buyers want more than a number slapped on a datasheet—they ask about lot-to-lot consistency, impurity profiling, and batch testing. Certification systems and audits also add another layer, reassuring end users and allowing traceability from raw material to final product. Improved transparency and communication between supplier and customer ensure that whatever the grade, the purity really matches the claim.

Glycine Methyl Ester Hydrochloride
Names
Preferred IUPAC name methyl 2-aminoacetate hydrochloride
Other names N-Methylglycine hydrochloride
Aminoacetic acid methyl ester hydrochloride
Methyl glycinate hydrochloride
Pronunciation /ˈɡlaɪsiːn ˈmɛθɪl ˈɛstər ˌhaɪdrəˈklɔːraɪd/
Identifiers
CAS Number 5680-79-5
3D model (JSmol) `/data/cml/mol/40/08/5.cml`
Beilstein Reference 1718733
ChEBI CHEBI:132786
ChEMBL CHEMBL1230532
ChemSpider 16213
DrugBank DB08323
ECHA InfoCard 03b4c6e0-3657-4816-8ff7-b810db80bb10
Gmelin Reference 7157
KEGG C00940
MeSH D02.241.223.150.280.500.400
PubChem CID 123210
RTECS number WH0700000
UNII MDU79M841Y
UN number UN2811
CompTox Dashboard (EPA) DTXSID9046762
Properties
Chemical formula C3H8ClNO2
Molar mass 125.57 g/mol
Appearance White to off-white crystalline powder
Odor Odorless
Density 0.98 g/cm3
Solubility in water Soluble in water
log P -3.2
Acidity (pKa) 2.4
Basicity (pKb) 8.96
Magnetic susceptibility (χ) -47.5 × 10⁻⁶ cm³/mol
Refractive index (nD) 1.488
Dipole moment 7.09 D
Thermochemistry
Std molar entropy (S⦵298) 151.8 J·mol⁻¹·K⁻¹
Pharmacology
ATC code A16AA12
Hazards
Main hazards Irritating to eyes, respiratory system, and skin.
GHS labelling GHS02, GHS07
Pictograms GHS05, GHS07
Signal word Warning
Hazard statements H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation.
Precautionary statements P264; P280; P305+P351+P338; P337+P313
NFPA 704 (fire diamond) 1-1-0
Flash point 132 °C
Autoignition temperature 400 °C
LD50 (median dose) > 5000 mg/kg (Rat, oral)
NIOSH Not listed
PEL (Permissible) Not established
REL (Recommended) 2-8°C
IDLH (Immediate danger) Not established
Related compounds
Related compounds Glycine
Glycine ethyl ester hydrochloride
Glycine methyl ester
Glycine tert-butyl ester hydrochloride
N-Methylglycine (Sarcosine)
Alanine methyl ester hydrochloride