© 2026 Nanjing Finechem Holdings Co., Ltd,
All Right Reserved
Chemical Name: Fluvoxamine Maleate
Chemical Family: Heterocyclic antidepressant
CAS Number: 61718-82-9
Synonyms: Luvox, Floxyfral, Faverin
Common Use: Prescription antidepressant for the treatment of obsessive-compulsive disorder and depression
GHS Classification: Not classified as hazardous for physical hazards, but may pose risk if misuse or accidental exposure occurs in bulk quantities
Acute Toxicity: Possible effects on central nervous system, serotonin syndrome, gastrointestinal upset
Chronic Effects: Prolonged exposure may impact mood, sleep, or cause withdrawal in therapeutic or high-dose scenarios
Eye Contact: May cause irritation, redness, or watering
Skin Contact: Risk of irritation can occur, especially with frequent handling
Inhalation: Fine powder may irritate respiratory tract or provoke allergic reactions in vulnerable individuals
Signal Word: Caution recommended for handling high concentrations; not classified as an immediate lethal hazard
Main Component: Fluvoxamine Maleate (>99% purity in clinical-grade batches)
Impurities: Residual solvents from synthesis, small amounts of related organic molecules
Additives: None in raw material; tablet preparations include lactose, cellulose, magnesium stearate
Inhalation: Remove to fresh air; monitor for dizziness or headache; seek medical help if discomfort persists
Skin Contact: Wash exposed area with soap and water; remove contaminated clothing
Eye Contact: Rinse gently with plenty of water for at least 15 minutes; avoid rubbing eyes
Ingestion: Rinse mouth, seek medical attention if large amounts are swallowed
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, or alcohol-resistant foam
Specific Hazards: Combustion yields toxic fumes such as carbon oxides, nitrogen oxides
Firefighter Protection: Wear full protective gear including self-contained breathing apparatus; prevent runoff from contaminating water supplies
Explosion Data: No known explosive properties under normal storage and handling conditions
Personal Precautions: Use gloves and eye protection; minimize dust formation
Containment: Collect spilled material using damp cloth or HEPA filter vacuum; avoid sweeping powder which may become airborne
Cleanup Method: Wash area with water and suitable detergent after collecting visible material; ventilate affected space
Handling: Avoid contact with skin and eyes; use in ventilated areas; avoid inhalation of powder
Storage Conditions: Store in tightly sealed containers, protected from moisture and direct sunlight
Temperature Guidelines: Keep at room temperature (15-30°C); avoid freezing or excessive heat
Incompatibilities: Store away from strong oxidizers and acids
Engineering Controls: Work in fume hood or with local exhaust ventilation when handling powders
Eye Protection: Safety goggles or face shield
Skin Protection: Nitrile gloves, protective clothing if risk of direct exposure persists
Respiratory Protection: Dust mask or NIOSH-approved respirator for large-scale operations or accidental releases
Hygiene Measures: Wash hands before breaks and after handling; change contaminated clothing
Appearance: White or off-white crystalline powder
Odor: Odorless or faint odor
Melting Point: Approximately 147-153°C
Solubility: Soluble in water and ethanol; insoluble in non-polar solvents
pH (1% solution): About 5-6
Vapor Pressure: Negligible at room temperature
Partition Coefficient (log Pow): 2.1, indicating moderate lipid solubility
Molecular Weight: 434.4 g/mol
Stability: Stable under recommended storage conditions
Reactivity: Not reactive with common materials under normal circumstances
Hazardous Decomposition: Burning yields harmful gases such as carbon monoxide, nitrogen oxides
Hazardous Polymerization: Not known to occur
Incompatible Materials: Strong oxidizers, acids may degrade product
Acute Oral Toxicity: LD50 (rat, oral) reported at approximately 600 mg/kg
Symptoms of Exposure: Drowsiness, nausea, headache, agitation, confusion, and rare risk of seizures at high doses
Possible Target Organs: Central nervous system, gastrointestinal tract
Carcinogenicity: No evidence of carcinogenicity in animal studies at therapeutic levels
Sensitization: Rare cases of allergic skin or respiratory responses in sensitive individuals
Mutagenicity: Negative in standard bacterial and mammalian cell assays
Aquatic Toxicity: Data limited, but like many pharmaceuticals, slow breakdown in aquatic environments raises potential risk to wildlife
Persistence and Degradability: Moderate persistence, as fluvoxamine is not readily biodegradable
Bioaccumulative Potential: Low based on chemical structure and partition coefficient, but metabolites may accumulate if released into ecosystems
Other Notes: Pharmaceuticals in wastewater prompt careful disposal and reduction at source
Waste Handling: Incinerate in a licensed chemical incinerator with afterburner and scrubber to control emissions
Fluid Disposal: Do not release to drains or surface water; avoid contamination of environment
Packaging Disposal: Dispose contaminated packaging by same protocols as active pharmaceutical waste
Local Regulations: Follow community and national drug disposal guidelines to prevent unintended spread and exposure
UN Number: Not assigned for fluvoxamine maleate in most jurisdictions
Proper Shipping Name: Pharmaceutical product, not regulated as hazardous for transport
Hazard Class: Not considered dangerous under international transport regulations
Environmental Hazards: Do not release during transport; secure containers against leakage
OSHA Status: Not specifically regulated as hazardous, though workplace safety laws still require precautions
TSCA Status: Exempt due to pharmaceutical use
REACH (EU): Not listed as a Substance of Very High Concern
Controlled Status: Prescription medication under national healthcare regulations; not scheduled under international conventions, but improper use or distribution may be subject to legal penalties
