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Product Name: 1,10-Phenanthroline
Chemical Name: 1,10-Phenanthroline
Formula: C12H8N2
Synonyms: o-Phenanthroline, ortho-Phenanthroline, 1,10-Phenanthrolin, Neocuproine
Manufacturer: Laboratory chemical suppliers
Product Use: Analytical chemistry, spectrophotometric reagent for metals, research
Contact Information: Emergency phone numbers typically available through chemical supplier; Responsible party or company listed on outer packaging
Hazard Classification: Acute oral toxicity (Category 3), Eye irritation (Category 2A), Skin irritation (Category 2)
Signal Word: Danger
Hazard Statements: Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. Harmful to aquatic life with long lasting effects.
Pictograms: Skull and crossbones, exclamation mark, environment
Routes of Exposure: Inhalation, ingestion, eye and skin contact
Target Organs: Gastrointestinal tract, skin, eyes
Precautionary Statements: Wear protective gloves/eye protection. Avoid breathing dust. Wash thoroughly after handling. Do not eat, drink, or smoke when using this product.
Chemical: 1,10-Phenanthroline
CAS Number: 66-71-7
EC Number: 200-629-2
Concentration: >99% (for laboratory grade material)
Impurities: Minor contaminants may occur, specific analysis required for trace metals and organic derivatives if relevant
Inhalation: Move person to fresh air. Provide artificial respiration if not breathing. Seek immediate medical advice.
Skin Contact: Rinse thoroughly with soap and water for at least 15 minutes. Remove contaminated clothing. Medical attention required for persistent irritation.
Eye Contact: Flush eyes immediately with water for 15 minutes lifting eyelids. Remove contacts if present and easy to do. Immediate medical attention encouraged.
Ingestion: Rinse mouth. Do not induce vomiting. Seek emergency medical help immediately.
Most Important Symptoms: Nausea, vomiting, abdominal pain, headache, redness or pain in eyes, skin inflammation
Advice for Physicians: Treat symptomatically and supportively. Gastric lavage for large ingestion; monitor for acute toxic effects.
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Unsuitable Media: No known incompatible materials
Special Hazards: Emits toxic nitrogen oxides and carbon oxides under fire conditions
Protective Equipment: Firefighters require self-contained breathing apparatus and full protective gear
Advice: Approach from upwind and avoid inhalation of combustion products. Cool surrounding containers with water spray.
Personal Precautions: Use respirators, gloves, protective safety eyewear, and avoid dust generation
Environmental Precautions: Prevent entry into drains, sewers, or soil; notify authorities if large quantities enter environment
Methods for Cleanup: Sweep or vacuum up material avoiding dust, place in labeled waste containers. Ventilate area. Wash spill area after pickup.
Safe Handling: Wear protective equipment; avoid breathing dust or contact with skin, eyes, or clothing. Use in fume hood if dust or aerosols could form.
Storage Conditions: Store in tightly closed original containers, in a dry, cool, well-ventilated area away from incompatible substances such as strong oxidizing agents.
Incompatibilities: Strong oxidizers, acids, some metals; keep away from moisture and direct sunlight
Engineering Controls: Ventilation to minimize dust and fume levels; local exhaust or fume hood recommended
Personal Protective Equipment: Lab coat, nitrile or neoprene gloves, chemical safety goggles, mask or respirator (NIOSH-approved) if dust risk present
Hygiene Measures: No eating, drinking, or smoking in work area. Wash hands after handling material.
Exposure Limits: No strict OSHA or ACGIH limits, but exposure should stay as low as practicable
Appearance: White to pale yellow crystalline powder
Odor: Odorless
Molecular Weight: 180.21 g/mol
pH: Not applicable (insoluble in water); forms weakly basic solutions when dissolved
Solubility: Very slightly soluble in water, soluble in ethanol, chloroform, acetic acid
Melting Point: 117 °C
Boiling Point: Decomposes before boiling
Flash Point: Not easily flammable
Vapor Pressure: Not volatile at room temperature
Density: 1.263 g/cm³
Chemical Stability: Stable under normal temperatures and recommended storage conditions
Reactivity: May react with strong oxidizing agents producing heat and toxic fumes
Conditions to Avoid: Excessive heat, open flame, moisture, long exposure to air or sunlight
Hazardous Decomposition Products: Nitrogen oxides, carbon oxides
Polymerization: Will not occur
Acute Toxicity: Oral LD50 (rat) estimated 132 mg/kg
Skin Corrosion/Irritation: Mild to moderate irritant in animal studies
Serious Eye Damage: Risk of irritation, redness, pain, tearing
Respiratory Sensitization: Dust may irritate respiratory tract; coughing and discomfort can result from exposure
Carcinogenicity, Mutagenicity, Reproductive Toxicity: Insufficient data for carcinogenicity; genotoxic and mutagenic effects observed in some studies at high exposures; not classified as an expected carcinogen
Other Effects: May cause gastrointestinal irritation, nausea, vomiting upon ingestion;
Chronic Effects: No well-documented chronic toxicity in humans; best handled with caution as for similar complexing agents
Aquatic Toxicity: Harmful to aquatic organisms, with possible long-term adverse effects in the aquatic environment. Acute and chronic toxicity should be anticipated for some aquatic species.
Persistence and Degradability: Not readily biodegradable, may persist in soil and sediment.
Bioaccumulative Potential: Moderate potential for bioaccumulation in aquatic life due to molecular structure.
Mobility in Soil: Low water solubility limits mobility, but may leach under certain conditions.
Other Adverse Effects: Release to groundwater or surface water should be managed strictly; avoid large-scale or routine disposal in the environment.
Waste Treatment Methods: Collect and dispose of via hazardous waste incinerator in accordance with local, regional, national, and international regulations
Contaminated Packaging: Rinse with suitable solvents; dispose of containers as hazardous laboratory waste
Do Not: Discharge into drains, surface water, or regular municipal trash systems. No disposal in household waste containers.
Recovery and Recycling: Not typically practical due to contamination risks; unused material should go to chemical waste facilities.
UN Number: UN2811 (Toxic solid, organic, n.o.s., if transporting regulated quantities above threshold)
ADR/RID: Class 6.1 toxic substances regulations for non-laboratory bulk transport
IMDG: Marine pollutant, class 6.1
IATA: Follows regulations for toxic solids, subject to packaging, quantity, and labeling constraints
Proper Shipping Name: Toxic solid, organic, n.o.s. (contains 1,10-phenanthroline)
Special Precautions: Ship in sealed, compatible containers, protected from damage, moisture, and extreme climates; emergency response documentation must accompany cargo
US Regulations: Not specifically listed in TSCA as a hazardous material but general workplace safety rules apply; recognized under SARA Title III for chemical inventory and reporting.
EU Regulations: CLP Regulation (EC) No 1272/2008 assigns acute oral toxicity, environmental hazard categories; chemical safety assessment may be required for bulk quantities.
Other Countries: Subject to workplace hazard labeling and use restrictions. Follow WHMIS (Canada), GHS, and local workplace requirements.
Label Requirements: Pictograms, hazard statements, precautionary measures, supplier identification must all appear on primary packaging.
