Yudu County, Ganzhou, Jiangxi, China sales3@ar-reagent.com 3170906422@qq.com
Follow us:



Looking Deeper Into Eosin Y Solution: A Staple in Diagnostic Color

Historical Development

Most of us probably remember the bright pink hue of eosin stains in biology class, even if we didn’t know the name. Eosin has been a mainstay in histology labs for more than a century, tracing back to its roots in the 19th century color chemistry boom. Researchers, seeking better ways to see inside biological cells, landed on these synthetic xanthene dyes to give vibrant contrast in tissue samples—turning cellular structures into readable maps under a microscope. Eosin Y, the yellowish-red version, found its stride thanks to its reliable binding with protein-rich cell regions, which makes it play nicely with hematoxylin in the classic H&E stain. Original batches came out of German dye houses, built off the discoveries of mainstream chemists looking to outdo natural dyes. Over time, Eosin Y solution became so essential that nearly every pathology or life sciences textbook features its sharply-defined color, and this pedigree links the dye directly to improved biological understanding and better diagnosis for countless patients.

Product Overview

A bottle of Eosin Y doesn’t usually get much attention outside the lab, but open it up and the striking pink-orange liquid is impossible to miss. It’s produced by dissolving Eosin Y dye—essentially a tetrabrominated derivative of fluorescein—in water, sometimes with alcohol as a solvent and acetic acid to fine-tune staining quality. The resulting solution gives scientists and technicians a reliable way to color proteins, cytoplasm, and extracellular matrix with good contrast and clarity. The “Y” corresponds to its slightly greenish-yellow cast in dry form, which gives tissues shades ranging from bright pink to deep red depending on how concentrated the solution is. Though you’ll find dozens of dye mixes in the scientific world, few have such a range of practical use as Eosin Y, from staining thin paraffin sections to coloring cytological smears or even working as a pH indicator in certain niche applications.

Physical & Chemical Properties

Eosin Y operates in a straightforward way. Its formula, C20H6Br4Na2O5, gives it enough heft to latch onto proteins, especially in slightly acidic environments. The solution is easily soluble in water and alcohol, leaving a bright fluorescent pink color that stands out even in small amounts. Under light, it can emit fluorescence with excitation at around 518 nm, which helps in advanced imaging. Its maximum absorption hovers near 515 nanometers. This dye doesn’t stay inert—mix it with acid, and the color shifts subtly, influenced by pH and ion concentration. Eosin Y’s physical stability means a bottle kept in a cool, dark place will last for years without losing its punch or staining power. This reliability accounts for much of its appeal; nobody wants a dye that fades or decomposes unpredictably in critical lab work.

Technical Specifications & Labeling

Labeling and handling Eosin Y solution require clear, accurate information, especially given its chemical complexity. Manufacturers must specify the concentration, usually reported in weight/volume, and indicate whether the base is sodium or potassium salt. The label tracks batch numbers for quality control and usually lists recommended shelf life and storage temperature. Clarity is vital here—many pathologists and technicians trust the label because mistakes can mess up staining results, leaving tissue slices unreadable or unreliable for diagnosis. Spec sheets typically state the dye’s purity and highlight the inclusion of solvents like alcohol or acetic acid, as these affect evaporation and staining characteristics. Each bottle should display hazard information, since the dye contains heavy bromines, and spill instructions for bench safety. Consistent, precise labeling does more than check regulatory boxes; it ensures every operator knows exactly how strong the solution is and how it interacts with protocols and other chemicals in the lab.

Preparation Method

Mixing up Eosin Y solution might sound simple, but many labs hold to rigorous preparation steps to keep staining results sharp and predictable. Technicians measure out Eosin Y powder using calibrated scales to get the correct weight for the solution, which is typically dissolved in distilled water or a water-ethanol mix. A dash of acetic acid tweaks the pH, enhancing staining brightness and helping the dye stick better to cytoplasmic proteins. The solution is then gently mixed until the powder fully dissolves, sometimes filtered through fine paper to remove particles. This filtered stock is protected from direct light to prevent photodegradation. Often, solution is prepared fresh at regular intervals—monthly or biweekly in busy labs—to prevent microbial contamination and safeguard quality. Such careful prep isn’t just tradition; it keeps diagnostic standards high and error rates low.

Chemical Reactions & Modifications

Eosin Y shows off its versatility through predictable chemical reactions with biological samples. Under acidic staining routines, it binds selectively to basic (positively charged) protein groups, giving reds and pinks that leap off the microscope slide. Researchers have experimented with derivatives and salt forms to alter solubility and adjust staining sensitivity. Tweaking the hydrocarbon structure or changing the associated cations, say from sodium to lithium, shifts staining outcomes, sometimes improving compatibility with newer automation systems in pathology. In photochemistry, Eosin Y plays a role as a photosensitizer, catalyzing free radical generation under light for polymerization and organic syntheses. While most labs stick to classic formulations, the broad chemistry has allowed some to modify the dye for more focused roles—such as environmentally sensitive stains or coupling with fluorescent tags for advanced imaging. These modifications don’t just upgrade performance; they help make staining protocols more precise and flexible across different tissue types.

Synonyms & Product Names

Anyone who’s spent time reading global literature or browsing supply catalogs knows Eosin Y hides behind a crowd of alternate names. Sometimes labeled as “Acid Red 87” or “CI 45380,” it also appears as “Eosin Yellowish” or “Bromo Fluorescein Sodium Salt.” In the lab, technicians toss around “Eosin Y” and “Eosin Y, disodium salt” interchangeably, depending on the recipe in use. Some suppliers market slight variations as “Eosin Y Solution, alcoholic” for the ethanol-heavy form or “Eosin Y aqueous” when dissolved mainly in water. These synonyms don’t just add confusion—they reflect the piecemeal, international way science grows, with every region, language, and discipline leaving its mark on the dye’s catalog numbers and nicknames.

Safety & Operational Standards

A bottle of Eosin Y demands more respect than its playful color suggests. Eosin Y contains bromine atoms, which raise toxicological red flags with overexposure. Lab safety guidelines demand gloves, eye protection, and careful ventilation when working with solutions—especially during large-scale staining or cleaning up spills. Many organizations like OSHA and the EU’s REACH program flag its waste as hazardous, even though acute effects in small-scale scientific staining are rare. Labs must store it away from incompatible organics and acids. It’s crucial to keep Eosin Y spill response and first-aid steps front of mind—stain on the counter is easy to wipe up, but accidental skin exposure, though rarely dangerous, can cause irritation. Proper records, training, and disposal practices don’t just meet bureaucratic requirements; they chip away at risks before they can interrupt research or harm workers.

Application Area

Pathology, histology, and cytology labs couldn’t function without Eosin Y solutions lining their shelves. This dye is a workhorse for differential cell staining, lending color balance to classic hematoxylin and eosin (H&E) slides. More than 90 percent of tissue-based cancer diagnostics worldwide rely on this pink colorant to highlight the background against deep blue nuclei. The dye doesn’t stop at medicine—botanists, microbiologists, and food technologists all use it to reveal structures invisible without chemical color. In some emerging fields, Eosin Y’s fluorescent behavior supports high-resolution imaging and photoactivation studies. Students and trainees all over the world first encounter scientific microscopy through Eosin-stained sections, making the solution as much a teaching tool as a diagnostic aid. Few reagents have such a broad, daily impact across science and education, making this dye solution one of the most heavily used, relied-on chemicals in any research building.

Research & Development

Despite more than a century on the books, Eosin Y draws regular attention from chemical researchers looking for smarter, cleaner, and more robust stains. Chemists have probed modifications that could bring down toxicity, cut the cost of synthesis, or open new doors in molecular imaging. A rising trend couples Eosin Y derivatives with nanoparticles to squeeze even sharper images out of tissue slides, hinting at future leaps in sensitivity for rare cell detection. Some researchers pursue greener synthetic routes, hoping to cut waste from traditional halogenation steps in hopes of meeting stricter environmental rules. Clinical researchers push for digital pathology tools that exploit the unique absorption spectra of Eosin Y—a move that could boost machine learning accuracy and drive automated diagnosis. I’ve seen the excitement firsthand when updated staining or imaging protocols using Eosin Y unlock easier diagnosis for conditions that once baffled practitioners. Each innovation, whether in the bottle or in the scanner, owes its foundation to the rock-solid reliability of this dye’s chemistry.

Toxicity Research

Eosin Y’s popularity has prompted plenty of research about health effects. At the concentrations used in staining, acute toxicity remains low, but researchers have found that large-scale or concentrated exposure could cause irritation or harm—with the brominated structure flagged for careful study. Toxicological reviews find little evidence linking trace lab exposure to major health issues in humans, but animal studies at high doses note irritation, especially in eyes and skin. Ecological impacts have been scrutinized since dyes persist in water and can affect aquatic life; effective waste treatment plays a key role in keeping labs compliant and communities safe. Industrial hygienists often monitor air and surface contamination in labs using Eosin Y and direct workers to safe handling habits. Most consensus says that regular lab-scale use under modern standards poses little threat, especially compared to older, more hazardous stains, but complacency in handling or disposal has no place where carcinogenic risk is left unstudied.

Future Prospects

Eosin Y’s story doesn’t pause with classic histology. As scientific imaging leans toward higher sensitivity and digital workflow, the dye will likely team up with new technologies rather than get replaced. Researchers aim to tweak its formula for less toxicity, deeper colors, or triggered fluorescence tailored to advanced microscopy. Emerging markets outside medicine—like materials science, plastics, and environmental monitoring—have started to explore Eosin Y’s photophysical properties for tasks far outside its original scope. Digital pathology platforms pull on the dye’s spectral signature for higher-accuracy computer vision, while photochemists see new roles in light-activated purification or green chemistry. These prospects bring responsibility: Scientists and manufacturers have to keep updating safety, handling, and waste disposal practices as applications expand. By focusing on reducing risk and maximizing information from each stained sample, the research and diagnostics community can keep putting Eosin Y’s strengths to work—sometimes revisiting a familiar pink slide, sometimes breaking new scientific ground.




What is Eosin Y Solution used for?

Why Eosin Y Matters in Science and Medicine

Anyone who’s stepped foot in a biology or pathology lab has probably seen a set of microscope slides showing off shades of pink and blue. That shade of pink doesn’t just happen. Eosin Y solution creates those colors. The stuff is a chemical stain, and its main job is to highlight cell parts when scientists look through a microscope.

Eosin Y makes cell structures stand out. Often paired with hematoxylin—together known as H&E stain—it tackles the tough job of turning invisible cells into clearly defined pictures. Hematoxylin turns nuclei blue, while Eosin Y colors the rest of the cell pink. This combo helps pathologists spot cancer, infections, and other diseases. I’ve always found it amazing how a splash of color can lift biological mysteries from the gray blur of tissue.

Clinic and Classroom Use

In a diagnostic setting, Eosin Y plays a frontline role. Pathologists rely on it to judge if a breast lump is just a cyst or something more serious. Thanks to these stains, tiny differences jump out under the lens. It doesn’t just stay in the hospital, either. Any medical or veterinary student learning to read slides will see Eosin Y in every basic practical lab. It makes complex cell shapes clear—even for beginners who aren’t sure what to look for yet.

Eosin Y in Research and Quality Control

Beyond medicine, Eosin Y adds value in fields like plant sciences and microbiology. It’s useful for studying fungi, identifying cell walls in plants, and even tracing certain chemical reactions. The predictable color change lets researchers confirm they are seeing the right structures. Years ago, I watched a friend use Eosin Y to mark up the edges of plant roots, helping our class unlock how water moves through those cells. Experiencing that firsthand made me realize how essential clear visualization remains, even today.

Potential Problems and Practical Challenges

Using Eosin Y solution takes some know-how. Too much dye can drown out fine details and make slides tough to interpret. Too little, and cells slip by unnoticed. Exposure can irritate skin or eyes, so labs stress the importance of gloves and safe handling. Some people worry about chemical runoff affecting water supplies, especially in places where waste disposal rules aren’t always enforced. More eco-friendly alternatives show promise, but for now, most labs can't do without Eosin Y.

Ideas for the Future

Lab safety keeps improving. I’ve seen newer training manuals put more focus on chemical safety and disposal. Some companies work on dyes with fewer environmental issues, aiming to keep the same clarity without the same risks. Open publishing of best practices helps spread safer staining habits, reaching schools and clinics that can’t afford new tech.

At the end of the day, Eosin Y’s importance rests in its ability to light up problems that can’t be solved in the dark. Science often depends on simple tools that open up a window into the body. Putting a spotlight—quite literally—on disease, development, and discovery, this solution keeps showing up in places where clear insights save lives.

How should Eosin Y Solution be stored?

Why Storage Choices Matter

Eosin Y Solution goes into labs all over the world. Pathologists and laboratorians pick it for its ability to bring out detail in tissue and cell samples. My own stretch in a microbiology lab taught me that even minor slips in storage can spell trouble. I watched slides turn off shades because a reagent bottle spent a night on a too-warm counter. Color accuracy, clarity, and even health risks connect to simple storage habits.

Temperature: Not Just a Suggestion

Every label and safety data sheet raises the same point: keep Eosin Y Solution cool. I’m not talking ice-cold or freezer range. Most protocols mark a range from 15 to 30 degrees Celsius, plain room temperature that stays steady. Fridges set too cold can cause precipitation, and high heat—like from sunny windows or workspace appliances—brings evaporation and breakdown. Any lab worker who’s found a cloudy pink sludge at the bottom of a bottle already knows what heat does.

Surveys from hospitals and research groups show that most chemical mishaps trace back to poor attention to temperature. Once, in my own experience, a colleague left Eosin Y by a radiator. By the time anyone caught it, the solution performed unevenly. Samples faded or gave strange stains, prompting retests and slowing the whole workflow.

Lids: Not Optional

More than one lab team has discovered the hard way that loose caps let Eosin Y evaporate or pick up dust. Strong dye solutions like this can put out fumes, so tight sealing protects air quality. Your own eyes will thank you next time you open the cabinet. A simple screw cap, checked after each use, stops spills and cross-contamination. This isn’t just about quality—it’s about safety. Breathing in vapors from long-open bottles irritates throats and eyes, especially with repeated exposure. Keeping containers sealed supports both the shelf life of the chemical and the health of the people around it.

Keeping Away from Direct Sunlight

Even a bottle of Eosin Y Solution tucked in the wrong spot—say, a windowsill shelf—can lose its punch. Light, especially sunlight, affects dyes pretty quickly. I learned the hard way while prepping microscope slides for a busy diagnostics service. A single session in strong daylight caused the solution’s color to shift, ruining a batch of tissue stains. Manufacturers warn about this in every decent reagent sheet, because direct light speeds up chemical reactions that break down the pigment.

Even indoor fluorescent lighting can have effects across months. Closed cabinets, bins marked for “light-sensitive” chemicals, or old-school brown-glass bottles add extra peace of mind. These approaches don’t take fancy equipment—just awareness and reminders.

Label Everything—And Keep it Clear

A lot of problems start because bottles lose their labels or students copy instructions sloppily. Every bottle of Eosin Y needs a clear label: name, concentration, and opening date. My lab notebook is full of reminders about checking expiry dates. Old, unstable solution can cause test failures or unpredictable results. Rotation—always grabbing the oldest bottle first—keeps supplies fresh and reduces unexpected headaches when someone grabs from the back of the shelf.

Building Better Storage Routines

From day one, most chemical safety training repeats: keep dyes like Eosin Y at steady temperatures, tightly capped, away from light, and always labeled. Reminders posted by storage cabinets go a long way. Assigning a staff member or student to check stock—making sure nothing is leaking, expired, or sitting in the sun—cuts down stress for everyone. Instead of hunting for a culprit after a botched test, problems get spotted early and fixed fast, and patient care or research moves forward.

Mistakes in storage almost always boil down to habits, not a lack of knowledge. By treating each step—temperature, lid, light, labels—as routine as washing hands, labs protect both the science and the scientists. Eosin Y remains a reliable partner, not a headache waiting in a bottle.

Is Eosin Y Solution safe for human use?

Looking at Safety Through Experience and Science

People know Eosin Y from biology class—those two pink drops mixing with cells on a glass slide. Eosin Y, a synthetic dye, highlights tissue detail under the microscope. Pathologists rely on it to tell healthy tissue from trouble. The label on the bottle might say “for laboratory use only” or “not for medical use,” so the question sticks: what would happen if this solution ended up where it shouldn’t—on skin, in the body, or even in food?

What the Science Says About Eosin Y

Chemically, Eosin Y belongs to a group of dyes called xanthene dyes. Scientists use it with hematoxylin as part of the famous “H&E stain” process in pathology labs everywhere. The National Center for Biotechnology Information and the European Chemicals Agency describe it as highly water-soluble, easy to apply, and strong in color. These properties make it great for slides, but not exactly friendly for human use beyond that.

Toxicologists have looked into Eosin Y. Studies in peer-reviewed journals point to a low risk of harm if a tiny amount touches healthy skin and gets washed off quickly. Still, that is not a green light for home skin treatments or cosmetics. Some experiments in animals, tracked by regulatory bodies, suggest irritation can develop if the solution stays on skin or gets in the eyes. Accidental swallowing leads to bigger risks: nausea, stomach pain, or worse, especially for kids.

The U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA) do not approve Eosin Y for any food, drug, or cosmetic purpose. These agencies draw clear lines. No legal use exists for the dye in creams, drops, injections, or foods people eat or drink. Pathologists also work in special labs that can control exposure. I remember spending my college summers around microscopes, wearing gloves, and cleaning anything touched with the solution. Even a fun experiment needed safety glasses and a working sink.

Cases Where Exposure Happened

An occasional story pops up about mislabeling or accidental exposure. Hospital records show that mistakes with dyes like Eosin Y almost always get caught fast, but rare accidents do happen. Medical literature describes a few cases of skin rashes, redness, and, on one occasion, mild chemical burns from prolonged skin contact. Every report highlights the need for prompt washing and keeping this dye far from eyes and mouths. Poison control centers log calls from parents whose kids got into laboratory chemicals at home or in schools. Nobody wants a household experiment to send a child to the ER.

Alternatives and Risk Reduction

Safe labeling and storage at home and school matter a lot. If art or science projects need colored solutions, food coloring or natural plant extracts work well. Paint companies and cosmetic labs test their colorants for months or years, proving safety before anyone can use them. In research and medicine, better barriers, training, and easy-to-read labels can keep Eosin Y in its lane—inside the laboratory, not out in kitchens or bathrooms.

The lesson feels clear. Eosin Y gives scientists great images under the microscope but carries no role in direct human use. Strong science backs this up, and experience in labs confirms it. Safety starts with respect for those limits.

What are the main applications of Eosin Y Solution in laboratories?

A Closer Look at Eosin Y

Step into almost any biology or medical lab and you’ll spot a gleaming glass bottle labeled “Eosin Y Solution” on a shelf. Ask any histotechnologist or research student what it’s for, and the answer comes quick: staining. Eosin Y stands as one of those ever-reliable tools you want in arm’s reach. Even though it’s just a dye, this single reagent shapes some of the clearest, most revealing microscope slides. The science baked into every drop transforms how scientists see tissue structure and detail.

Bringing Color to the Picture in Histology

Most memories from my time handling tissue samples involve stains. You take a thin slice of animal organ, mount it on a glass slide, and without a dye, the whole thing looks barely different from a tiny, clear piece of plastic. Eosin Y fixes that problem. Its main job? Highlighting parts of cells that are otherwise hard to see. It binds to proteins in the cytoplasm, muscle fibers, and red blood cells, turning them various shades of pink or red. The contrast it builds helps pathologists spot abnormalities—tumors, inflammation, or even subtle degenerative changes. Without this level of staining, diagnosing disease would require a lot more guesswork and error.

Stronger Results with Hematoxylin and Eosin (H&E) Staining

Eosin Y gets paired with hematoxylin as the foundation for H&E staining, easily the world’s most used histological stain. Hematoxylin turns cell nuclei a dark purple or blue, then Eosin Y comes in and colors the rest. This split in color tells seasoned scientists exactly what they need at a glance. It’s possible to identify cell types, structures, and any odd-looking clusters just by looking for the right shades. Every teaching hospital, research lab, and pathology department relies on this system. Papers published in medical journals hinge on results made possible by these stains.

Vital Staining in Microbiology and Hematology

Outside of tissue analysis, Eosin Y serves up helpful insights in other biology fields. Take hematology: Eosin Y stains red blood cells, making it possible to spot different types or identify odd changes linked to blood disorders. In microbiology, it can help highlight bacteria, fungi, or parasites mixed in blood or tissue. This boosts the odds of catching an infection early. During my own research projects, I learned fast that a properly stained slide could cut hours off microscope work and lead to more confident conclusions.

Quality Control and Reproducibility

Every result in a lab depends on the tools holding up under the same conditions time after time. Eosin Y Solution is standardized across suppliers, so results from one slide can be matched to those from a lab across the country. Scientists and clinicians rely on this consistency to share information, train new staff, and review old samples. Without quality stains, years of archived specimens would lose their value, making it hard for hospitals and universities to prove a diagnosis or teach the next generation.

Moving Forward: Sustainability and Alternatives

Chemical safety and environmental concerns shape a lot of today’s lab practices. Eosin Y contains chemicals that need careful disposal. Labs work to limit waste and explore safer alternatives, but right now, nothing matches the quality and reliability it provides. Tips that helped me: use only the amount needed, store it safely, and always follow disposal guidelines. Researchers keep looking for greener substitutes, yet until they catch up, the best approach stays careful, informed use.

What is the shelf life of Eosin Y Solution?

Why Eosin Y Matters in Labs

Eosin Y solution gives countless medical and biological labs their color and clarity. It’s a vital part of staining processes, especially for those of us who’ve squinted at microscope slides, trying to tell eosinophilic cytoplasm from nuclei. Trained lab staff, histologists, and pathologists rely on the consistency of this dye to support diagnoses and research. If Eosin Y starts to degrade or break down, that accurate, bright pink stain can fade or shift, foiling essential work. I remember seeing uneven slides in college labs and assuming some error on my end—only to learn the solution had expired and lost potency.

Shelf Life: What Are We Working With?

In most labs, Eosin Y solution is stored in dark bottles, sitting on shelves far from direct sunlight. This classic dye, a xanthene derivative, holds up surprisingly well—usually, manufacturers and quality guidelines give it about two years from date of manufacture if left unopened and kept in cool, dry shelves. Opened bottles don’t last as long. Once you crack that seal, contamination, evaporation, and air exposure start shortening the window. Most labs that rely on best practices replace in-use Eosin Y every six months to a year.

Keeping Eosin Y Fresh

Always check the label for the manufacturer’s recommended expiry. Never trust just the color in the bottle. Faded, cloudy, or streaky stains on your histology slides can mean degradation, which might come from exposure to heat, UV light, or microbial contamination. Common-sense steps extend that shelf life: store bottles tightly capped, in the fridge or a cool cabinet, away from light, and never double dip pipettes. Throw away any solution that looks off or smells odd.

Risks of Using Old Dye

Labs running on a tight budget sometimes try to stretch every last drop. Cutting costs here introduces risk. Inferior staining with expired Eosin Y can obscure readings—either masking details or creating spurious artifacts that waste time and money or even lead to misdiagnosis. Regulatory bodies, from the College of American Pathologists to the FDA, flag expired reagents as a key violation. Re-inspections, failed certifications, and patient safety all get wrapped up in one bad bottle. In my experience, nothing sets off a panic among med techs quite like finding expired Eosin tucked behind fresher stock.

Building Better Lab Practices

For those managing the storeroom or lab bench, simple routines keep everybody working safely. Log expiry dates in a visible spot and rotate stock so old bottles get used first or discarded on time. Batch testing occasionally with control slides helps catch declining performance early. Buying in reasonable quantities, in line with real usage, stops Eosin Y from piling up unused and going bad. Training staff to spot and report any change in stain quality saves trouble before problems start.

Protecting Outcomes and Patients

Eosin Y doesn’t last forever, and taking shelf life for granted costs real-world reliability. Keeping dyes fresh and potent is a routine task that underpins accuracy in pathology—and, indirectly, good patient care. That’s not some abstract issue; it shows respect for the diagnostic process and for the people standing behind the microscope.

Eosin Y Solution
Names
Preferred IUPAC name Tetra­bromo­fluorescein
Other names Eosin Yellowish Solution
Eosin Y
Acid Red 87 Solution
C.I. 45380 Solution
Pronunciation /ˈiːə.sɪn waɪ səˈluː.ʃən/
Identifiers
CAS Number 17372-87-1
Beilstein Reference 4009367
ChEBI CHEBI:51831
ChEMBL CHEMBL1287391
ChemSpider 503680
DrugBank DB01698
ECHA InfoCard 07f6fc55-2a8a-415c-93d5-5f15b8a29dac
EC Number 202-618-6
Gmelin Reference 81121
KEGG C08288
MeSH Dyes, Staining and Labeling Agents
PubChem CID 5281239
RTECS number KM0450000
UNII VJI12K8O56
UN number UN1993
CompTox Dashboard (EPA) DTXSID3048627
Properties
Chemical formula C20H6Br4Na2O5
Molar mass 691.85 g/mol
Appearance Red solution
Odor Odorless
Density 1.01 g/cm³
Solubility in water Soluble in water
log P -0.95
Acidity (pKa) 2.0
Basicity (pKb) pKb: 11.0
Magnetic susceptibility (χ) -48.0e-6 cm³/mol
Refractive index (nD) 1.334
Viscosity Viscous liquid
Dipole moment 0.00 D
Pharmacology
ATC code D08AB02
Hazards
Main hazards Harmful if swallowed. Causes serious eye irritation.
GHS labelling GHS02, GHS07, GHS08
Pictograms GHS07,GHS09
Signal word Warning
Hazard statements H302 + H312 + H332: Harmful if swallowed, in contact with skin or if inhaled.
Precautionary statements P264, P280, P305+P351+P338, P337+P313
NFPA 704 (fire diamond) 2-1-0
Flash point Flash point: >100°C
Lethal dose or concentration LD₅₀ Oral - rat - 7,200 mg/kg
LD50 (median dose) LD50 (median dose): Oral, rat: 3300 mg/kg
PEL (Permissible) PEL: 15 mg/m3 (total dust), 5 mg/m3 (respirable fraction)
REL (Recommended) 1%
Related compounds
Related compounds Eosin
Eosin B
Phloxine B
Rose Bengal
Fluorescein