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Chemical Name: Edetate Disodium
Synonyms: Disodium ethylenediaminetetraacetate, Disodium EDTA
CAS Number: 139-33-3
Molecular Formula: C10H14N2Na2O8
Recommended Use: Laboratory reagent, chelating agent in various industries, food preservative, water treatment chemical, pharmaceutical excipient
Supplier and Emergency Contact: Identify supplier-specific details for spill, exposure, or safety information.
GHS Classification: Not classified as hazardous according to the Globally Harmonized System
Potential Health Effects: Eye and skin irritation after direct or prolonged contact; respiratory tract irritation from dust inhalation
Overview of Main Hazards: Not known to be acutely toxic but chronic exposure may affect kidney function and mineral metabolism; large quantities may cause gastrointestinal discomfort if ingested
Signal Word: None required based on typical usage concentrations
Pictogram: Not assigned
Precaution Statement: Avoid breathing dust, use personal protective equipment as needed, wash hands thoroughly after handling
Chemical Batch Components: Disodium ethylenediaminetetraacetate: 98-100%
Impurities and Stabilizing Additives: Minor traces of sodium chloride or other sodium salts possible depending on production; specify batch if needed
Eye Contact: Rinse cautiously with water for several minutes, lift eyelids, continue rinsing; seek medical attention if irritation persists
Skin Contact: Remove contaminated clothing, wash with soap and water, seek medical help for persistent irritation
Inhalation: Move to fresh air, seek medical attention if symptoms like coughing or shortness of breath develop
Ingestion: Rinse mouth, do not induce vomiting, drink water if alert, seek medical help for large exposures or symptoms
Suitable Extinguishing Media: Use water spray, dry chemical, foam, or carbon dioxide
Unsuitable Extinguishing Media: Direct water jets may spread powder
Specific Hazards Arising from Chemical: Thermal decomposition may release irritating fumes containing oxides of nitrogen and carbon
Advice for Firefighters: Wear self-contained breathing apparatus, protective clothing, maintain safe distance, use water spray to cool containers
Personal Precautions: Avoid dust formation, ventilate area, use personal protective equipment like gloves, masks, and goggles
Environmental Precautions: Prevent buildup in waterways, avoid discharge in drains without proper dilution
Clean-Up Methods: Sweep up, place in suitable marked container for disposal, wash spill site after material pickup is complete
Handling: Avoid contact with skin, eyes, and clothing, minimize dust generation and accumulation, use local exhaust ventilation, wash hands thoroughly after handling
Storage Conditions: Store in cool, dry area, keep containers tightly closed, protect from moisture and incompatible materials like strong acids or oxidizers
Storage Incompatibility: Avoid contact with strong acids due to possibility of toxic gas formation, segregate from oxidizing agents
Occupational Exposure Limits: Not set for disodium EDTA, follow recommended general dust exposure standards (e.g., ACGIH TLV for particulates not otherwise classified: 10 mg/m³ total dust)
Engineering Controls: Work under local exhaust ventilation or in well-ventilated area
Personal Protective Equipment: Use gloves, safety goggles, lab coat or suitable clothing, dust masks or respirators for prolonged exposure
Hygiene Measures: Do not eat, drink, or smoke in work area, wash thoroughly after handling, remove contaminated clothing and wash before reuse
Appearance: White, crystalline powder
Odor: Odorless
pH: 4-6 (1% aqueous solution)
Melting Point: Decomposes above 240°C
Solubility in Water: Freely soluble
Boiling Point: Not applicable (decomposes)
Vapor Pressure: Negligible
Density: 0.86-0.89 g/cm³
Partition Coefficient (n-octanol/water): Not available
Auto-ignition Temperature: Not self-igniting
Flash Point: Not flammable
Decomposition Temperature: Above 240°C
Chemical Stability: Stable under normal temperatures and pressure, may decompose at higher temperatures
Reactivity: May react with strong acids to form toxic gases
Hazardous Decomposition Products: Nitrogen oxides, carbon dioxide, carbon monoxide
Conditions to Avoid: Excess heat, moisture, contact with incompatible materials including acids and oxidizers
Routes of Exposure: Inhalation, ingestion, skin, and eye contact
Acute Toxicity: Oral LD50 (rat): 2000-4000 mg/kg; can cause nausea, vomiting, abdominal pain if ingested in large quantities
Chronic Effects: Long-term exposure may affect kidney function and mineral balance
Irritation: Dust can cause irritation to eyes and mucous membranes
Carcinogenicity: Not listed as a carcinogen by IARC, ACGIH, NTP, or OSHA
Reproductive Toxicity: No evidence from standard studies
Sensitization: Not classified as a skin sensitizer
Aquatic Toxicity: Moderate; LC50 (fathead minnow): approximately 41 mg/L (96 hr)
Persistence and Degradability: Less biodegradable; chelates may persist in water and may mobilize heavy metals
Bioaccumulative Potential: Does not bioaccumulate in aquatic organisms
Environmental Fate: Can alter availability of metal ions in soil and water; excessive concentrations may affect aquatic life
Mobility in Soil: High mobility due to water solubility
Disposal Method: Dispose according to local, regional, and national regulations; recommended to incinerate or landfill with class-approved waste handlers
Contaminated Packaging: Rinse thoroughly before discarding or recycling; puncture and dispose of empty containers as chemical waste
Precautions: Do not allow material to enter sewers, surface water, or soil in large amounts
UN Number: Not regulated for transport
Transport Hazard Class: No hazard class assigned
Packing Group: Not assigned
Proper Shipping Name: Edetate disodium or EDTA disodium
Special Precautions for User: Keep container sealed and dry during transport; avoid spillage
Labelling According to Regulation: Not classified as hazardous for supply/use
TSCA Status: Listed on the US Toxic Substances Control Act inventory
REACH: Registered in accordance with European regulations
California Proposition 65: Does not contain chemicals known to the State of California to cause cancer or reproductive toxicity
Other Information: Ensure workplace safety programs account for dust exposure; review local environmental and health regulations before use
