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Product Name: Diisopropyl Ether
Synonyms: Isopropyl Ether, 2-Isopropoxypropane, Propane, 2,2'-oxybis[1-methylethane]
CAS Number: 108-20-3
Recommended Uses: Solvent in laboratories, extractions, chemical synthesis
Supplier: Check local supplier details or direct from manufacturer
Physical Hazards: Highly flammable liquid and vapor; may form explosive peroxides on prolonged contact with air.
Health Hazards: Vapors may cause irritation of eyes, nose, throat, and respiratory tract; may cause central nervous system depression, headache, drowsiness, dizziness, nausea; prolonged exposure can result in liver or kidney effects.
Environmental Hazards: Toxic to aquatic life; benzene formation risk during improper disposal.
Signal Word: Danger
Hazard Pictograms: Flame, exclamation mark, health hazard
Precautionary Statements: Keep away from heat sources, sparks, open flames; avoid breathing vapor and contact with skin or eyes; use only with adequate ventilation.
Chemical Name: Diisopropyl Ether
Common Name: Isopropyl Ether
Concentration: 99% or above (technical grade)
CAS Number: 108-20-3
Impurities: Small quantities of peroxides may develop with exposure to air and light.
Inhalation: Remove victim to fresh air immediately; provide oxygen if breathing is difficult; seek medical attention if symptoms persist.
Skin Contact: Wash skin with plenty of soap and water for at least 15 minutes; remove contaminated clothing; consult physician if skin irritation develops.
Eye Contact: Flush eyes with running water for at least 15 minutes, lifting eyelids; seek immediate medical attention.
Ingestion: Do not induce vomiting; rinse mouth with water; never give anything by mouth to an unconscious person; call poison center or physician right away.
Suitable Extinguishing Media: Carbon dioxide, dry chem, alcohol-resistant foam; water spray to cool containers.
Unsuitable Extinguishing Media: Direct water jet may spread fire.
Fire Hazards: Extremely flammable; vapor can travel to ignition source; explosive mixtures possible; containers may explode in heat.
Protective Equipment for Firefighters: Full protective gear; self-contained breathing apparatus required.
Special Instructions: Avoid inhaling combustion gases; evacuate area; keep containers cool with water mist.
Personal Precautions: Evacuate personnel from area; eliminate ignition sources; provide proper ventilation.
Protective Equipment: Chemical-resistant gloves, protective clothing, goggles, suitable respirator.
Environmental Precautions: Prevent run-off to sewers; contain spill with inert material such as sand.
Clean-up Methods: Absorb with non-combustible absorbent; place in chemical waste container for disposal; ventilate affected area after clean-up.
Handling: Use only in areas with good airflow; ground and bond containers when transferring; avoid contact with heat, sparks, or flame; minimize exposure to air to reduce peroxide formation.
Storage: Store in tightly closed containers; keep containers in cool, dry, well-ventilated location away from direct sunlight, oxidizers, acids, and heat sources; check regularly for peroxide contamination.
Special precautions: Use proper containers made from compatible materials (steel, glass); periodically test stored material for peroxide content.
Occupational Exposure Limits: OSHA TWA: 250 ppm (1060 mg/m3); ACGIH TWA: 250 ppm
Engineering Controls: Fume hood or local exhaust; explosion-proof equipment.
Personal Protection: Chemical splash goggles, nitrile or neoprene gloves, lab coat, impervious footwear.
Respiratory Protection: NIOSH-approved respirator if ventilation does not control exposure.
Hygiene Measures: Wash hands after handling; do not eat, drink, smoke in use areas; remove contaminated clothing before leaving work area.
Appearance: Colorless, mobile liquid
Odor: Characteristic sweet, ether-like
Odor Threshold: About 50 ppm
Boiling Point: 68-69°C
Melting Point: -60°C
Vapor Pressure: 132 mmHg at 20°C
Vapor Density: 3.5 (air = 1)
Specific Gravity: 0.724 at 20°C
Solubility in Water: 0.88 g/100mL at 20°C
Flash Point: -28°C
Autoignition Temperature: 415°C
Explosion Limits: 1.4% (LEL) – 22% (UEL)
Partition Coefficient (log Pow): 1.55
Chemical Stability: Stable if stored below 30°C, in dry environment, away from light; forms explosive peroxides upon prolonged air exposure.
Possibility of Hazardous Reactions: Risk of violent reaction with oxidizing agents; exothermic reactions with strong acids.
Conditions to Avoid: Heat, sparks, open flames, sources of peroxide formation (air, light), incompatible materials.
Incompatible Materials: Oxidizing agents (nitric acid, perchlorates), acids.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, peroxides.
Acute Toxicity: Oral LD50 (rat): 1410 mg/kg; inhalation LC50 (rat, 4hr): 17 g/m3
Exposure Symptoms: Respiratory irritation, headaches, drowsiness, central nervous system depression, ataxia, confusion, unconsciousness at high concentrations.
Skin Corrosion/Irritation: Mild to moderate irritation on repeated contact.
Eye Damage/Irritation: Causes irritation, redness, tearing.
Chronic Exposure: May cause liver and kidney effects, possible reproductive toxicity based on animal studies at high doses.
Sensitization: No evidence in laboratory animals.
Carcinogenicity: Not classified by IARC, NTP, OSHA.
Ecotoxicity: Harmful to aquatic organisms; EC50 (daphnia, 48h): 230 mg/L.
Persistence and Degradability: Readily biodegradable (about 60% in 28 days, aerobic conditions).
Bioaccumulation Potential: Low potential based on log Pow.
Mobility in Soil: Mobile in soils; can reach groundwater if spilled.
Other Adverse Effects: Volatile organic compound contributing to air pollution and smog formation.
Waste Disposal Methods: Dispose in accordance with local, state, federal regulations; avoid discharge to environment; incinerate in approved facility.
Container Disposal: Empty containers follow same precautions as product due to peroxide risk; puncture, triple rinse, and recycle if allowed.
Precautions: Check for peroxide formation before distillation or incineration.
UN Number: UN 1159
UN Proper Shipping Name: Diisopropyl Ether
Transport Hazard Class: 3 (Flammable Liquid)
Packing Group: II
Marine Pollutant: Not listed, but take care to prevent aquatic release.
Special Precautions: Use approved, properly labeled containers; keep away from heat, sparks, open flames throughout transport.
OSHA: Regulated as hazardous chemical;
EPA: Listed on TSCA inventory; SARA 313 not subject;
EU Regulation: Conforms to REACH and CLP standards;
WHMIS (Canada): B2 (Flammable Liquid), D2B (Toxic);
Label Elements: Flammable liquid symbol, Harmful health statements;
Other International: Subject to chemical regulations in most industrialized countries.
