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Dihydrocapsaicin: The MSDS Details That Matter

Identification

Chemical Name: Dihydrocapsaicin
Other Names: 8-Methyl-N-vanillyl-6-nonenamide
Chemical Formula: C18H29NO3
Common Uses: Used in research for its effects on pain receptors, found in chili peppers, and often present in spicy foods and extracts
Appearance: White to off-white crystalline powder
Odor: Faint, slightly pepper-like
Solubility: Soluble in alcohol, ether, and oils, low solubility in water

Hazard Identification

GHS Classification: Causes skin, eye, and respiratory irritation
Signal Word: Warning
Hazard Statements: May cause serious eye and skin irritation, can provoke strong burning sensation on contact, harmful if swallowed, harmful if inhaled
Precautionary Statements: Avoid breathing dust or fumes, wash hands thoroughly after handling, use personal protection

Composition / Information on Ingredients

Main Ingredient: Dihydrocapsaicin (purity typically above 90%)
Impurities: Trace amounts of related capsaicinoids may be present

First Aid Measures

Inhalation: Remove to fresh air, seek medical attention for symptoms such as irritation or difficulty breathing
Skin Contact: Wash with soap and plenty of cool water, keep affected area exposed to air, seek medical help for persistent burning sensation
Eye Contact: Rinse immediately with plenty of water for at least 15 minutes, avoid rubbing, contact a healthcare provider
Ingestion: Rinse mouth, drink water, do not induce vomiting, consult a medical professional

Fire-Fighting Measures

Suitable Extinguishing Media: Use foam, carbon dioxide, dry chemical, or water spray
Specific Hazards: Can emit toxic fumes of carbon dioxide or carbon monoxide on combustion
Protective Equipment: Firefighters need standard protective gear, including a self-contained breathing apparatus

Accidental Release Measures

Personal Precautions: Wear gloves, goggles, mask, protective clothing
Environmental Precautions: Prevent entry into drains, waterways, or soil
Cleanup Methods: Sweep up without creating dust, use wet paper towels, dispose of material in a closed container, ventilate the area

Handling and Storage

Precautions: Keep container tightly closed, handle in a well-ventilated place, wear appropriate personal protective equipment
Storage Conditions: Store in cool, dry, and well-ventilated area, keep away from strong oxidizers and acids
Incompatibilities: Avoid exposure to heat, flames, or moisture

Exposure Controls and Personal Protection

Engineering Controls: Work in fume hood or well-ventilated area
Personal Protective Equipment: Use gloves, safety goggles, dust mask or respirator, lab coat
Hygiene Measures: Wash hands thoroughly after use, remove contaminated clothing and wash before reuse

Physical and Chemical Properties

State: Solid
Color: White to off-white
Odor: Slight, peppery
Melting Point: Ranges around 65-67°C
Boiling Point: Data not widely reported
Solubility: Miscible in alcohols, slightly soluble in water
Density: No broad consensus, but estimate around 1 g/cm3

Stability and Reactivity

Chemical Stability: Stable at normal temperatures in storage
Reactivity: Does not react significantly with common materials at room temperature
Conditions to Avoid: Excess heat, light, moisture,
Incompatible Materials: Strong oxidizing agents
Hazardous Decomposition Products: Thermal breakdown can create carbon monoxide, carbon dioxide

Toxicological Information

Acute Effects: Strong irritant to skin, eyes, and mucous membranes, burning sensations, coughing
Ingestion Hazards: May cause gastrointestinal upset, burning in mouth, throat
Long-term Exposure: Potential for chronic irritation, few studies for long-term systemic toxicity, not classified as carcinogenic
Sensitization: Can sensitize skin with repeated contact

Ecological Information

Aquatic Toxicity: Not classified with strong evidence as dangerous to aquatic life, may still cause localized harm at high concentrations
Persistence: Expected to break down over time due to natural processes
Bioaccumulation: No evidence of significant bioaccumulation

Disposal Considerations

Waste Treatment Methods: Dispose as hazardous waste following local, regional, and national regulations
Packaging Disposal: Triple-rinse empty containers before landfill, or incinerate in controlled facility

Transport Information

UN Number: Not formally regulated for transport in small laboratory quantities
Transport Hazard Class: Not classified as dangerous for ground, air, or sea transport
Packing Group: Not applicable for most common handling cases

Regulatory Information

Labelling Requirements: Requires clear labels noting irritant, and safety statements for laboratory environments
Regulatory Status: Generally managed as a laboratory chemical, not subject to major international chemical conventions for restricted chemicals
Workplace Exposure Limits: No established occupational exposure limit but good industrial hygiene recommends exposure be kept as low as practical