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Material Safety Data Sheet: Difenilcarbazida

Identification

Product Name: Difenilcarbazida
Chemical Name: 1,5-Diphenylcarbazide
CAS Number: 140-22-7
Synonyms: Diphenylcarbazide, 1,5-Diphenylcarbazide
Recommended Use: Analytical reagent, especially for detecting chromium.
Supplier: Information available from manufacturer or distributor.
Emergency Contact: Refer to local regulations and registered safety lines.

Hazard Identification

Classification: Acute Toxicity (Oral, Category 4), Eye Irritation (Category 2A), Skin Sensitizer (Category 1B).
Signal Word: Warning
Hazard Statements: Harmful if swallowed. May cause an allergic skin reaction. Causes serious eye irritation.
Pictograms: Exclamation mark.
Precautionary Statements: Wash thoroughly after handling. Do not eat, drink, or smoke when using this product. Wear protective gloves and eye protection.
Potential Health Effects: Inhalation may irritate the respiratory tract. Contact with skin may cause sensitization. Serious eye damage may result from direct exposure.

Composition / Information on Ingredients

Chemical Name: Difenilcarbazida
CAS Number: 140-22-7
Concentration: >98% Pure
Impurities: Trace solvents or residual raw materials possible, typically below 2%.
Additives: None expected in analytical grade samples.

First Aid Measures

Inhalation: Remove person to fresh air. Seek medical advice if symptoms like coughing or breathing difficulty develop.
Skin Contact: Remove contaminated clothing. Wash area with soap and water for at least 15 minutes. Get medical attention if irritation or sensitization occurs.
Eye Contact: Rinse carefully with plenty of water for several minutes. Remove contact lenses. Get medical attention if irritation persists.
Ingestion: Rinse mouth thoroughly. Give small quantities of water if conscious. Do not induce vomiting. Seek immediate medical attention.
Specific Symptoms: Redness, itching, rash (skin); tearing, burning (eyes); headache, nausea (ingestion or inhalation).
Advice for Physicians: Treat symptomatically based on clinical findings.

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical powder, CO2, foam. Avoid water jets.
Hazards from Combustion: Toxic gases such as carbon monoxide, carbon dioxide, nitrogen oxides may occur.
Protective Equipment: Wear self-contained breathing apparatus and full protective gear.
Firefighting Procedures: Move containers from fire area if it can be done without risk. Cool exposed containers with water spray.
Explosion Risks: No known explosion hazard under normal conditions, but dust may form explosive mixtures with air.

Accidental Release Measures

Personal Precautions: Evacuate unnecessary personnel. Avoid breathing dust. Use proper personal protective equipment.
Environmental Precautions: Prevent entry to drains, surface waters, and soil.
Clean-up Methods: Sweep up and place in a suitable, labeled container for disposal. Avoid creating airborne dust.
Decontamination: Wash spill area with plenty of water after collection of solid material.
Disposal: Handle collected material as hazardous waste, following all local and national regulations.

Handling and Storage

Handling: Store and use in a well-ventilated workspace. Minimize dust generation. Do not eat, drink, or smoke while handling the chemical.
Hygiene: Wash hands and any exposed skin after use. Remove contaminated clothing and wash before reuse.
Storage Conditions: Keep tightly closed in original container. Store in a cool, dry place, protected from light and moisture.
Incompatible Materials: Strong oxidizers, acids, or bases may react with difenilcarbazida.
Storage Temperature: Recommended at room temperature, away from direct sunlight and heat sources.

Exposure Controls and Personal Protection

Occupational Exposure Limit: No specific limit established. Avoid excessive exposure.
Engineering Controls: Use local exhaust ventilation to keep airborne concentrations low. Safety shower and eyewash stations should be accessible.
Personal Protective Equipment: Protective gloves (nitrile preferred), safety goggles, lab coat, dust mask or respirator where dust may be generated.
Environmental Exposure Controls: Prevent release into the environment.
Workplace Practices: Regular cleaning of work surfaces. No open food or drink.

Physical and Chemical Properties

Appearance: White to pale pink powder.
Odor: Odorless.
Molecular Formula: C13H14N4O
Molecular Weight: 226.28 g/mol
Melting Point: 156–158°C
Solubility: Slightly soluble in water; soluble in ethanol, acetone, chloroform.
Boiling Point: Not applicable (decomposes).
Vapor Pressure: Not available.
Density: Not available.
pH Value: Not applicable (solid form).
Flash Point: Not available.

Stability and Reactivity

Chemical Stability: Stable under recommended storage and handling.
Reactivity: No hazardous reactivity known under normal conditions.
Conditions to Avoid: Excessive heat, open flames, moisture, direct sunlight.
Incompatible Materials: Strong oxidizing agents, acids, bases.
Hazardous Decomposition Products: Carbon oxides, nitrogen oxides, potentially toxic organic fragments upon decomposition.

Toxicological Information

Likely Routes of Exposure: Skin contact, eye contact, ingestion, inhalation.
Acute Toxicity: LD50 (oral, rat) approximately 300 mg/kg.
Skin Corrosion/Irritation: May cause irritation or allergic reaction.
Serious Eye Damage/Irritation: Serious irritation possible.
Respiratory Sensitization: Dust may cause discomfort or allergic response in sensitive individuals.
Chronic Effects: Long-term exposure data not fully available. No classified mutagenic or carcinogenic potential by current guidelines.

Ecological Information

Aquatic Toxicity: Data limited. Potentially harmful to aquatic life at significant concentrations.
Persistence and Degradability: Expected to persist under normal environmental conditions, degradability data lacking.
Bioaccumulative Potential: No reliable data available. Molecular structure suggests bioaccumulation is unlikely.
Mobility In Soil: Probably low due to low water solubility.
Other Adverse Effects: Avoid disposal to natural ecosystems, as detailed impact remains under-researched.

Disposal Considerations

Waste Disposal Methods: Dispose as hazardous chemical waste following approved local, regional, and national guidelines.
Container Disposal: Triple rinse and puncture before disposal, or incinerate if regulations permit.
Do Not Release: Do not wash into drains, waterways, or ground soil.
Incineration: Preferred treatment for large quantities with approved emission control.

Transport Information

UN Number: Not classified as hazardous for transportation under most current legal frameworks.
Proper Shipping Name: Difenilcarbazida
Transport Hazard Classes: Not regulated.
Packing Group: Not regulated.
Environmental Hazards: Not a marine pollutant.
Special Precautions: Use secondary containment and appropriate protective packaging.

Regulatory Information

Safety, Health, and Environmental Regulations: Subject to workplace safety regulations and hazardous substances management under OSHA in the US, CLP Regulation in the EU, and similar frameworks globally.
Inventory Status: Listed on TSCA (USA), EINECS (EU), and other major inventories.
Labeling: Conforms to GHS labelling (hazard pictogram, signal word, hazard and precautionary statements).
Restrictions: For professional, lab use only. Not for food, drug, or household use.
Other Regulations: Waste management required for production and use. Safety assessments recommended before usage outside laboratory settings.