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Material Safety Data Sheet
D-Fructose

Identification

Product Name: D-Fructose
Synonyms: Fruit Sugar, Levulose
Chemical Formula: C6H12O6
Molecular Weight: 180.16 g/mol
CAS Number: 57-48-7
Recommended Use: Food ingredient, laboratory reagent, pharmaceutical applications
Manufacturer Information: Supplier's details printed on packaging
Emergency Contact: Chemtrec 1-800-424-9300 (USA), local emergency numbers worldwide

Hazard Identification

Classification: Not classified as hazardous by GHS
Physical Hazards: May form combustible dust concentrations in air
Health Hazards: Inhalation of dust can cause coughing and respiratory discomfort. Repeated skin contact may provoke mild irritation.
Label Elements: Dust warning, handle cautiously to avoid inhaling powder
Environmental Hazards: No known significant effects to the environment
Precautionary Statements: Minimize dust generation, avoid contact with eyes and prolonged skin contact

Composition / Information on Ingredients

Chemical Identity: D-Fructose
Purity: More than 98%
Impurities: Minimal, may include moisture and trace byproducts from crystallization
Common Adulterants: None in reagent-grade material; food-grade sources may contain minor glucose

First Aid Measures

Inhalation: Remove individual to fresh air, seek medical aid if breathing remains difficult
Skin Contact: Wash with soap and water, remove contaminated clothing
Eye Contact: Flush eyes thoroughly with water for at least fifteen minutes, lift eyelids if needed
Ingestion: Rinse mouth, drink water, medical attention rarely necessary except for large accidental ingestion or allergic reaction
Most Important Symptoms: Temporary discomfort to eyes, skin, respiratory tract
Advice for Immediate Medical Attention: Provide product label and packaging if advanced care required

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, dry chemical, foam, or carbon dioxide
Unsuitable Media: Direct stream of water may spread burning powder
Hazardous Combustion Products: Carbon monoxide, carbon dioxide
Special Firefighting Procedures: Firefighters need approved self-contained breathing apparatus and protective gear
Advice for Emergency Workers: Keep upwind from fire, avoid inhaling combustion fumes, cool containers exposed to fire

Accidental Release Measures

Personal Precautions: Avoid dust formation, ventilate area, wear dust mask and gloves
Environmental Precautions: Prevent entry into drains and water sources in bulk amounts
Methods for Clean-Up: Sweep up gently, avoid raising dust, place into labeled containers for reuse or disposal, wash residual material with water
Reference to Other Sections: Follow instructions for personal protective equipment and handling

Handling and Storage

Precautions for Safe Handling: Minimize creation of airborne dust, handle with clean dry tools, use proper grounding if transferring large amounts
Hygiene Practices: Wash hands and exposed surfaces before eating, drinking, or using restroom; keep contaminated clothing separate
Storage Conditions: Store in tightly closed container at room temperature, dry, and away from direct sunlight
Suitable Materials for Containers: Glass, plastic, food-grade metal canisters
Incompatibilities: Strong oxidizers, sources of ignition

Exposure Controls and Personal Protection

Occupational Exposure Limits: No specific OSHA, ACGIH, or NIOSH limits for fructose as a chemical
Engineering Controls: Proper exhaust and local ventilation to minimize airborne dust
Respiratory Protection: Approved dust mask or respirator if powder becomes airborne
Skin Protection: Standard laboratory or food-handling gloves
Eye Protection: Safety glasses or chemical splash goggles
General Protective Measures: Clean work area regularly to prevent buildup of powder residues, wash after work

Physical and Chemical Properties

Appearance: White, crystalline powder or granules
Odor: Odorless or faintly sweet
Taste: Distinct sweet taste
Melting Point: 103–105°C
Boiling Point: Decomposes before boiling
Solubility: Easily soluble in water
Density: 1.59 g/cm³
pH (solution): Slightly acidic, 4–7 in 10% aqueous solution
Vapor Pressure: Negligible under standard conditions
Flash Point: Not highly flammable, but combustible as fine powder
Explosion Limits: Dust can pose explosion hazard in air at high concentrations

Stability and Reactivity

Chemical Stability: Stable under typical storage and handling conditions
Reactivity: Not reactive under expected conditions
Hazardous Reactions: May react with strong oxidizers; generates carbon oxides on burning
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide if burned
Conditions to Avoid: Exposure to extreme heat, contact with strong acids or oxidizers, high humidity
Polymerization: Will not occur

Toxicological Information

Acute Toxicity: Very low toxicity, LD50 (oral, rat) >15,000 mg/kg
Skin Corrosion/Irritation: Practically non-irritant
Eye Damage/Irritation: Mild irritation possible upon contact
Respiratory Sensitization: Possible discomfort on inhalation of dust
Carcinogenicity: Not regarded as carcinogenic by IARC, NTP, OSHA
Mutagenicity: No evidence in regulatory testing
Chronic Exposure: Not associated with chronic toxic effects under normal handling

Ecological Information

Ecotoxicity: Not toxic to aquatic or terrestrial organisms in usual concentrations
Persistence and Degradability: Readily biodegradable, does not persist in environment
Bioaccumulation: Not expected to bioaccumulate
Mobility in Soil: Highly soluble, will be diluted and broken down by soil microorganisms
Other Adverse Effects: High concentrations in waterways may alter osmotic balance and disrupt aquatic organisms

Disposal Considerations

Waste Treatment Methods: Dispose of in accordance with local, regional, and national regulations
Recommended Disposal: Dissolve small quantities in water and flush to drain if approved by authorities; larger amounts handled at licensed waste facility
Packaging Disposal: Rinse empty containers before recycling or disposing as general waste
Precautions: Keep dust generation as low as possible during handling and disposal

Transport Information

UN Number: Not regulated
UN Proper Shipping Name: Not regulated
Transport Hazard Class: Non-hazardous material
Packing Group: Not applicable
Marine Pollutant: Not classified
Special Precautions: Package to avoid moisture, shipping in clean, sealed, appropriately labeled containers
Transport Notes: No restriction for air, sea, or road transport under standard guidelines

Regulatory Information

OSHA Status: Not listed as hazardous chemical
TSCA Status: Listed on United States TSCA inventory
EU REACH Status: Registered substance for food, pharmaceutical, and chemical uses
SARA Title III: Not reportable under Sections 302, 304, 313
California Proposition 65: Not listed
Other International Listings: Approved as food additive in majority of countries globally
Labeling Requirements: Standard label with ingredient identification, dust hazard if sold in industrial-sized sacks