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Product Name: Curcumin
Synonyms: Turmeric yellow, Diferuloylmethane
Chemical Formula: C21H20O6
CAS Number: 458-37-7
Manufacturer: Common suppliers include major chemical distributors and botanical extract companies. Detailed manufacturer contact information helps trace the source for authenticity checks and safety queries.
Recommended Use: Laboratory research, food colorant, supplement ingredient.
GHS Classification: Not classified as hazardous under most global standards
Hazard Statements: May cause eye, skin, or respiratory irritation in sensitive persons
Signal Word: None required
Precautionary Statements: Avoid breathing dust, wash skin thoroughly after handling, wear protective equipment
Routes of Exposure: Inhalation, skin, eyes
Chemical Name: Curcumin
Concentration: Typically ranges from 80 to 95% in commercial extracts
Impurities: Small amounts of demethoxycurcumin and bisdemethoxycurcumin may occur
Additives: None unless listed by specific manufacturer in blended products
Inhalation: Move to fresh air. Keep comfortable for breathing. Seek medical attention if symptoms such as cough or wheezing persist.
Skin Contact: Wash affected area thoroughly with soap and water. Remove contaminated clothing. Seek attention if skin irritation or rash develops.
Eye Contact: Rinse gently with water for at least 15 minutes. Remove contact lenses if present and easy to do. If irritation continues, consult a healthcare provider.
Ingestion: Rinse mouth with water. Do not induce vomiting. Medical advice is recommended for large amounts, for sensitive individuals, or if symptoms develop.
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Hazards from Combustion: Emits hazardous fumes such as carbon monoxide and carbon dioxide if heated to decomposition
Protective Equipment: Firefighters use standard protective clothing and self-contained breathing apparatus
Fire Precautions: Avoid dust accumulation as fine particulates may present explosion risk in confined spaces
Personal Precautions: Wear appropriate personal protective equipment including gloves, eye protection, and mask for dust
Environmental Precautions: Prevent product from entering drains, sewers, or waterways
Clean-Up Methods: Sweep up carefully to avoid dust generation and transfer to suitable labeled containers for disposal; clean spill area with water and detergent
Safe Handling: Use only with adequate ventilation. Avoid generating dust. Do not eat, drink, or smoke during use. Wash hands after handling.
Storage Conditions: Keep container tightly closed in a cool, dry, and well-ventilated location. Protect from moisture, direct sunlight, and heat sources. Store away from incompatible substances, especially strong oxidizers.
Exposure Limits: No occupational exposure limits established for curcumin
Engineering Controls: Local exhaust ventilation recommended for bulk handling
Personal Protection: Use safety glasses or goggles, impervious gloves for skin protection, and an approved dust mask or respirator for airborne powder
Hygiene Measures: Practice good industrial hygiene, such as changing out of contaminated clothing and washing hands before eating or drinking
Appearance: Yellow-orange crystalline powder
Odor: Mild, earthy
Odor Threshold: Not available
pH: Not determined in solid form
Melting Point: 183°C
Solubility: Low solubility in water, higher in ethanol, acetone, and oils
Boiling Point: Decomposes
Flash Point: Not available
Vapor Pressure: Negligible under normal ambient conditions
Partition Coefficient (n-octanol/water): logP = ~3.2
Chemical Stability: Stable at recommended storage conditions; decomposes with heat, light or exposure to strong oxidizing agents
Reactive Materials: Strong oxidizers, strong bases
Hazardous Reactions: No hazardous polymerization
Decomposition: May emit toxic fumes such as carbon oxides when heated to breakdown
Routes of Exposure: Inhalation, skin, eye, ingestion
Acute Toxicity Data: Oral LD50 (rat) > 2,000 mg/kg
Skin Corrosion/Irritation: Generally mild, but sensitization and dermatitis reported in rare cases
Eye Damage/Irritation: May cause temporary irritation
Chronic Effects: No confirmed carcinogenic, mutagenic, or teratogenic effects in humans at normal exposure; animal studies suggest potential for liver and GI effects at high doses
Sensitization: Some individuals develop allergic reactions on skin contact or inhalation
Ecotoxicity: Not expected to present acute hazard to aquatic environment at typical concentrations
Persistence and Degradability: Readily biodegradable in environmental conditions due to natural origin
Bioaccumulation: Low potential; logP suggests some partitioning into aquatic organisms is possible but no evidence of buildup
Mobility: Low water solubility limits travel in groundwater but spills on soil may be taken up by runoff
Waste Treatment Methods: Collect waste in suitably labeled containers. Disposal must comply with local, regional, and national regulations.
Product Disposal: Small quantities can be landfilled according to local legislation. Large quantities should be incinerated or disposed of through licensed waste treatment facilities.
Contaminated Packaging: Empty containers retain dust and residue; dispose according to official requirements.
UN Number: Not regulated for transport
UN Proper Shipping Name: Curcumin is not classified as hazardous for international transport
Transport Hazard Class: Non-dangerous as per ADR, ICAO/IATA, and IMDG codes
Packing Group: Not applicable
Other Information: Keep containers tightly sealed and protected during transport
International Inventories: Listed in the TSCA (USA), EINECS/ELINCS (Europe), DSL (Canada), and AICS (Australia)
Regulatory Status: Approved for use in food and supplements by several regulatory agencies; occupational and consumer exposure usually considered safe within recommended limits
Labeling Requirements: No special labeling required for hazardous content, but food-grade labeling and compliance necessary for consumable products
