© 2026 Nanjing Finechem Holdings Co., Ltd,
All Right Reserved
Chemical Name: Cloruro de Dansilo
Common Names: Dansyl chloride, DNS-Cl
Synonyms: 5-(Dimethylamino)naphthalene-1-sulfonyl chloride
Product Code: DNSC2024
CAS Number: 605-65-2
Manufacturer: (Specify manufacturer contact details, address, phone, and emergency contact)
Recommended Use: Laboratory reagent, derivatizing agent for amines
Restrictions on Use: Industrial and research only, not for drug, household or food use
GHS Classification: Acute toxicity (Oral, Inhalation, Dermal); Skin corrosion/irritation; Serious eye damage/eye irritation; Specific target organ toxicity (single exposure); STOT (repeated exposure); Environmental hazard (aquatic)
Pictograms: Skull and crossbones, exclamation mark, corrosive, environment
Signal Word: Danger
Hazard Statements: Harmful if swallowed, causes severe skin burns and serious eye damage, may cause respiratory irritation, toxic to aquatic life
Precautionary Statements: Wear protective gloves, avoid breathing dust, wash hands thoroughly after handling, use only outdoors or in a well-ventilated area, avoid release to the environment
Chemical Formula: C12H12ClNO2S
Concentration: 98–100%
Impurities: Trace organic and inorganic compounds (momentary incidental presence)
Main Hazardous Ingredients: Dansyl chloride forms toxic and corrosive gases if decomposed or exposed to moisture
Additives: None
Stabilizers: None present in standard containers; product stability relies on storage environment
Inhalation: Move to fresh air immediately, keep person calm and warm, seek medical advice quickly. If not breathing, perform artificial respiration. Monitor for respiratory distress and seek emergency help.
Skin Contact: Remove contaminated clothing, wash skin thoroughly with soap and water for at least 15 minutes, seek medical attention if irritation develops. Monitor for blistering or persistent redness.
Eye Contact: Rinse with plenty of water for at least 15 minutes lifting eyelids, remove contact lenses if present and easy to do, seek immediate medical attention.
Ingestion: Rinse mouth, do not attempt to induce vomiting, get immediate medical attention, give water only if conscious and alert.
Most Important Symptoms and Effects: Severe irritation, burning sensation, coughing, difficulty breathing, visual disturbance, potential delayed effects on the liver or kidneys
Suitable Extinguishing Media: Dry chemical, carbon dioxide, foam, water spray for larger fires
Unsuitable Extinguishing Media: Direct stream of water (may spread corrosive liquid or dust)
Hazards from Combustion: Hydrogen chloride, sulfur oxides, nitrogen oxides, toxic organic dust
Protective Equipment for Firefighters: Self-contained breathing apparatus (SCBA) and full protective gear
Special Precautions: Avoid runoff into drains, keep containers cool using water spray, isolate fire area and deny unnecessary entry. Remove containers from fire area if possible to do safely.
Personal Precautions: Evacuate unnecessary personnel, ventilate area, avoid breathing vapors, prevent skin and eye contact using appropriate PPE (gloves, goggles, protective clothing)
Emergency Procedures: If respiratory risk is present use a NIOSH-approved respirator, block off spill area
Environmental Precautions: Prevent spillage from entering drains or waterways, cover drains, collect spills with inert absorbent material
Method for Containment: Sweep or scoop up in a manner minimizing dust, transfer to suitable closed container for disposal
Clean-up: Wash affected area with water and detergent after material is collected, dispose contaminated materials as hazardous waste
Safe Handling: Use only in a chemical fume hood, avoid inhaling dust/vapor, avoid skin or eye exposure, keep containers tightly closed, never work alone with this chemical
Hygiene Measures: Wash hands thoroughly after handling, remove and wash contaminated clothing before reuse
Storage Conditions: Store in original tightly sealed container, keep away from heat, moisture, strong acids, bases, oxidizers; maintain in a dry, well-ventilated, secure location
Incompatible Materials: Water, strong bases, strong acids, strong oxidizers
Packing Materials: Use original containers, glass preferred, secondary containment should be considered to prevent spillage
Exposure Limits: No established OSHA or ACGIH exposure limit; minimize exposure as low as reasonably practicable
Engineering Controls: Chemical fume hood, closed transfer where possible, mechanical exhaust to prevent airborne dusts/vapors
Personal Protective Equipment: Chemical-resistant gloves (nitrile, neoprene), safety goggles or face shield, lab coat, protective apron, respiratory protection (NIOSH approved) if dust/vapor is present or above recommended exposure
General Protective and Hygienic Measures: Avoid eating, drinking, smoking in work areas, wash hands thoroughly after handling, remove contaminated clothing and equipment before exiting work area
Appearance: Pale yellow crystalline solid
Odor: Mild aromatic odor
Odor Threshold: Not established
pH: Not applicable (solid)
Melting Point: 71–73°C
Boiling Point: Decomposes
Flash Point: Not established (solid, organic chloride)
Evaporation Rate: Not determined
Flammability: Combustible solid
Upper/Lower Flammability or Explosive Limits: Not determined
Vapor Pressure: Low at room temperature
Vapor Density: Not determined
Solubility: Decomposes in water, soluble in organic solvents (acetone, acetonitrile, chloroform)
Partition coefficient (n-octanol/water): Not determined
Auto-ignition Temperature: Not determined
Decomposition Temperature: Begins to decompose near melting point
Viscosity: Not applicable
Molecular Weight: 269.75 g/mol
Chemical Stability: Stable under recommended storage, decomposes in presence of moisture or water with release of HCl and sulfonic acid
Reactive Hazards: Hydrolyzes with moisture, forms corrosive gases, reacts violently with strong bases, acids, oxidizers
Conditions to Avoid: Exposure to water, humidity, strong heat sources, incompatible materials
Incompatible Materials: Water, strong bases or oxidizers, acids, alcohols
Hazardous Decomposition Products: Hydrogen chloride, sulfur oxides, nitrogen oxides, organic vapors
Polymerization Hazards: No hazardous polymerization expected
Likely Routes of Exposure: Inhalation, skin and eye contact, accidental ingestion
Acute Toxicity: Harmful by ingestion, inhalation, or skin absorption; causes severe irritation and burns
Skin Corrosion/Irritation: Burns and blistering possible
Serious Eye Damage/Irritation: Causes severe burns, permanent eye injury possible
Respiratory Effects: Irritation, coughing, shortness of breath, chest tightness
Chronic Effects: Prolonged exposure can cause organ damage especially liver and kidneys
Carcinogenicity: No classification by IARC, ACGIH, NTP, OSHA
Mutagenicity/Reproductive Toxicity: Insufficient data
Symptoms of Overexposure: Severe irritation, blistering, redness, watery eyes, corneal damage, chemical pneumonia possible
Ecotoxicity: Toxic to aquatic life, possible long-term adverse effects in aquatic environments
Persistence and Degradability: Low environmental persistence if rapidly hydrolyzed, but sulfonyl chloride byproduct can be problematic
Bioaccumulative Potential: No data, not expected to bioaccumulate significantly
Mobility in Soil: Mobile if released due to water solubility of break-down products though original compound is less mobile
Other Adverse Effects: Avoid release to water bodies, rivers, drains or sewage systems; reaction with water forms acidic and toxic byproducts
Waste Disposal Methods: Dispose as hazardous chemical waste in accordance with local, regional, national regulations; do not discharge to environment
Waste Packaging: Dispose of empty containers as hazardous waste; triple rinse containers and render unusable
Recycling/Incineration: Chemical incineration in a licensed facility preferred, avoid landfill disposal
Special Precautions: Avoid spillage, leaks, and dust formation during waste handling
UN Number: UN 3261
UN Proper Shipping Name: Corrosive Solid, Acidic, Organic, n.o.s. (contains dansyl chloride)
Transport Hazard Class: 8 (Corrosive)
Packing Group: II
Marine Pollutant: Yes
Labeling Requirements: Corrosive symbol, UN number, hazard class
Special Precautions for User: Avoid physical damage, keep container closed and secured, keep from water and incompatible substances
Additional Transport Information: Transport only by trained personnel, vehicle must be equipped for hazardous chemical response, emergency guidelines must be carried with shipment
OSHA Status: Hazardous chemical per OSHA Hazard Communication Standard
TSCA Status: Listed on TSCA inventory
Other Regulations: Subject to SARA Title III Section 313; State-specific chemical safety acts may apply
REACH Annex Status: Not registered or restricted under REACH
WHMIS Classification (Canada): Class E (Corrosive), Class D2B (Toxic materials with other chronic effects)
Labeling Requirements: Proper chemical identification, GHS symbols, hazard and precautionary statements
International Regulations: Transport and trade restrictions may apply depending on end use and destination country
